Page last updated: 2024-10-22

amlodipine and Dementia, Vascular

amlodipine has been researched along with Dementia, Vascular in 3 studies

Amlodipine: A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.
amlodipine : A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.

Dementia, Vascular: An imprecise term referring to dementia associated with CEREBROVASCULAR DISORDERS, including CEREBRAL INFARCTION (single or multiple), and conditions associated with chronic BRAIN ISCHEMIA. Diffuse, cortical, and subcortical subtypes have been described. (From Gerontol Geriatr 1998 Feb;31(1):36-44)

Research Excerpts

ExcerptRelevanceReference
"Vascular dementia is the second most common cause of dementia affecting over seven million people worldwide, yet there are no licensed treatments."2.82A randomised controlled trial of calcium channel blockade (CCB) with Amlodipine For the treatment oF subcortical ischaEmic vasCular demenTia (AFFECT): study protocol. ( Arrojo, F; Ballard, C; Bath, P; Canning, R; Connelly, P; Corbett, A; Coulthard, E; Greenan, C; Henderson, C; Holmes, C; Jones, R; Kehoe, PG; Knapp, M; McGuinness, B; Murphy, L; O'Sullivan, M; Passmore, P; Stewart, R; Thomas, A; Wallach, S; Yu, LM, 2016)
"Hypertension is the major risk factor for SVDs, but how hypertension damages the brain microcirculation is unclear."1.62Differential restoration of functional hyperemia by antihypertensive drug classes in hypertension-related cerebral small vessel disease. ( Dabertrand, F; Ferris, HR; Greenstein, AS; Harraz, OF; Hill-Eubanks, DC; Koide, M; Longden, TA; Nelson, MT; Wellman, GC, 2021)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Yao, KX1
Lyu, H1
Liao, MH1
Yang, L1
Gao, YP1
Liu, QB1
Wang, CK1
Lu, YM1
Jiang, GJ1
Han, F1
Wang, P1
Koide, M1
Harraz, OF1
Dabertrand, F1
Longden, TA1
Ferris, HR1
Wellman, GC1
Hill-Eubanks, DC1
Greenstein, AS1
Nelson, MT1
Greenan, C1
Murphy, L1
Yu, LM1
Kehoe, PG1
Coulthard, E1
Bath, P1
Stewart, R1
Jones, R1
Corbett, A1
Thomas, A1
Connelly, P1
Arrojo, F1
Canning, R1
Wallach, S1
Henderson, C1
McGuinness, B1
O'Sullivan, M1
Holmes, C1
Knapp, M1
Ballard, C1
Passmore, P1

Trials

1 trial available for amlodipine and Dementia, Vascular

ArticleYear
A randomised controlled trial of calcium channel blockade (CCB) with Amlodipine For the treatment oF subcortical ischaEmic vasCular demenTia (AFFECT): study protocol.
    Trials, 2016, 07-18, Volume: 17, Issue:1

    Topics: Activities of Daily Living; Amlodipine; Brain Ischemia; Calcium Channel Blockers; Clinical Protocols

2016

Other Studies

2 other studies available for amlodipine and Dementia, Vascular

ArticleYear
Effect of low-dose Levamlodipine Besylate in the treatment of vascular dementia.
    Scientific reports, 2019, 12-03, Volume: 9, Issue:1

    Topics: Amlodipine; Animals; Astrocytes; Blood Vessels; Dementia, Vascular; Disease Models, Animal; Mice; Mi

2019
Differential restoration of functional hyperemia by antihypertensive drug classes in hypertension-related cerebral small vessel disease.
    The Journal of clinical investigation, 2021, 09-15, Volume: 131, Issue:18

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Cerebral Smal

2021