Page last updated: 2024-10-22

amlodipine and Cirrhosis

amlodipine has been researched along with Cirrhosis in 18 studies

Amlodipine: A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.
amlodipine : A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.

Research Excerpts

ExcerptRelevanceReference
" The aim of the present study was to examine the effect of a novel ARB, olmesartan, on myocardial function of the left ventricle in patients with mildto-moderate hypertension."9.14Olmesartan ameliorates myocardial function independent of blood pressure control in patients with mild-to-moderate hypertension. ( Futai, R; Ito, T; Kawanishi, Y; Kitaura, Y; Terasaki, F, 2009)
" The authors hypothesized that reduction in aldosterone production in diabetes by amlodipine or aliskiren improves diabetic kidney disease by attenuating renal oxidative stress and fibrosis."7.79Reduction of aldosterone production improves renal oxidative stress and fibrosis in diabetic rats. ( Matavelli, LC; Siragy, HM, 2013)
"The aim of the present study was to compare the cardioprotective properties of long-acting calcium channel antagonist pranidipine with amlodipine in rat model of heart failure induced by autoimmune myocarditis."7.73Comparative effects of pranidipine with amlodipine in rats with heart failure. ( Aizawa, Y; Gurusamy, N; Kamal, FA; Kodama, M; Kunisaki, M; Ma, M; Mito, S; Palaniyandi, SS; Prakash, P; Veeraveedu, PT; Wahed, MI; Watanabe, K; Wen, J, 2006)
"Thirty-nine ESRD patients with hypertension were randomly assigned to receive losartan (n=13), enalapril (n=13), or amlodipine (n=13)."6.71Impact of the angiotensin II receptor antagonist, losartan, on myocardial fibrosis in patients with end-stage renal disease: assessment by ultrasonic integrated backscatter and biochemical markers. ( Iwasaka, T; Masaki, H; Matsubara, H; Matsumoto, N; Mori, Y; Nishikawa, M; Nishiue, T; Shibasaki, Y; Tamura, K, 2005)
"To compare the effects of losartan and amlodipine on myocardial structure and function in hypertensive patients with Type 2 diabetes and left ventricular hypertrophy."5.16Losartan and amlodipine on myocardial structure and function: a prospective, randomized, clinical trial. ( Corradi, L; Derosa, G; Destro, M; Fogari, R; Lazzari, P; Mugellini, A; Preti, P; Zoppi, A, 2012)
" The aim of the present study was to examine the effect of a novel ARB, olmesartan, on myocardial function of the left ventricle in patients with mildto-moderate hypertension."5.14Olmesartan ameliorates myocardial function independent of blood pressure control in patients with mild-to-moderate hypertension. ( Futai, R; Ito, T; Kawanishi, Y; Kitaura, Y; Terasaki, F, 2009)
" The authors hypothesized that reduction in aldosterone production in diabetes by amlodipine or aliskiren improves diabetic kidney disease by attenuating renal oxidative stress and fibrosis."3.79Reduction of aldosterone production improves renal oxidative stress and fibrosis in diabetic rats. ( Matavelli, LC; Siragy, HM, 2013)
" In the present study, we evaluated the effect of an ARB, olmesartan medoxomil (CS866), on the progression of peritoneal fibrosis in peritoneal dialysis by examining its effect in a model of peritoneal fibrosis in hypertensive rats."3.74Role of the renin-angiotensin system in the pathogenesis of peritoneal fibrosis. ( Fukushima, R; Imai, H; Ishida, Y; Nakamoto, H; Suzuki, H; Yamanouchi, Y, 2008)
"The aim of the present study was to compare the cardioprotective properties of long-acting calcium channel antagonist pranidipine with amlodipine in rat model of heart failure induced by autoimmune myocarditis."3.73Comparative effects of pranidipine with amlodipine in rats with heart failure. ( Aizawa, Y; Gurusamy, N; Kamal, FA; Kodama, M; Kunisaki, M; Ma, M; Mito, S; Palaniyandi, SS; Prakash, P; Veeraveedu, PT; Wahed, MI; Watanabe, K; Wen, J, 2006)
" The lowest dosage of lacidipine (but not of amlodipine) restored the physiological downregulation of renin production by high salt and reduced left ventricular hypertrophy and mRNA levels of atrial natriuretic factor and transforming growth factor-beta1."3.71Effects of amlodipine and lacidipine on cardiac remodelling and renin production in salt-loaded stroke-prone hypertensive rats. ( Godfraind, T; Krenek, P; Kyselovic, J; Wibo, M, 2001)
"Thirty-nine ESRD patients with hypertension were randomly assigned to receive losartan (n=13), enalapril (n=13), or amlodipine (n=13)."2.71Impact of the angiotensin II receptor antagonist, losartan, on myocardial fibrosis in patients with end-stage renal disease: assessment by ultrasonic integrated backscatter and biochemical markers. ( Iwasaka, T; Masaki, H; Matsubara, H; Matsumoto, N; Mori, Y; Nishikawa, M; Nishiue, T; Shibasaki, Y; Tamura, K, 2005)
"Treatment with carvedilol or amlodipine completely prevented left ventricular collagen deposition and morphometric alterations in aorta."1.46Effects of carvedilol or amlodipine on target organ damage in L-NAME hypertensive rats: their relationship with blood pressure variability. ( Berg, G; Bertera, FM; Carranza, A; Chiappetta, DA; Del Mauro, JS; Donato, M; Fernandez Machulsky, N; Gelpi, RJ; González, GE; Gorzalczany, SB; Höcht, C; Morales, C; Morettón, MA; Prince, PD; Taira, CA, 2017)
"Telmisartan is an angiotensin II receptor blocker, which acts as a partial agonist of peroxisome proliferator activator receptor-γ (PPAR-γ)."1.38Different roles of PPAR-γ activity on physiological and pathological alteration after myocardial ischemia. ( Hirata, Y; Hishikari, K; Isobe, M; Masumura, M; Nagai, R; Nagashima, A; Ogawa, M; Shimizu, T; Suzuki, J; Takayama, K; Watanabe, R, 2012)
"The treatment with amlodipine reduced SBP but failed to ameliorate the ADMA-induced histological changes."1.34Role of asymmetric dimethylarginine in vascular injury in transgenic mice overexpressing dimethylarginie dimethylaminohydrolase 2. ( Hasegawa, K; Hayashi, K; Homma, K; Itoh, H; Kimoto, M; Sugano, N; Tatematsu, S; Wakino, S; Yoshioka, K, 2007)
"The transgenics developed left ventricular hypertrophy along with perivascular and interstitial fibrosis which became progressively worse up to 24 weeks of age."1.31Raised blood pressure, not renin-angiotensin systems, causes cardiac fibrosis in TGR m(Ren2)27 rats. ( Bishop, JE; Gohlke, P; Kiernan, LA; McEwan, JR; Montgomery, HE, 2000)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's11 (61.11)29.6817
2010's7 (38.89)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Del Mauro, JS1
Prince, PD1
Donato, M1
Fernandez Machulsky, N1
Morettón, MA1
González, GE1
Bertera, FM1
Carranza, A1
Gorzalczany, SB1
Chiappetta, DA1
Berg, G1
Morales, C1
Gelpi, RJ1
Taira, CA1
Höcht, C1
Nelson, JW1
Ferdaus, MZ1
McCormick, JA1
Minnier, J1
Kaul, S1
Ellison, DH1
Barnes, AP1
Honma, S1
Nakamura, K1
Shinohara, M1
Mitazaki, S1
Abe, S1
Yoshida, M1
Nakamoto, H1
Imai, H1
Fukushima, R1
Ishida, Y1
Yamanouchi, Y1
Suzuki, H1
Lu, JC1
Cui, W1
Zhang, HL1
Liu, F1
Han, M1
Liu, DM1
Yin, HN1
Zhang, K1
Du, J2
Fan, YY1
Hitomi, H1
Kiyomoto, H1
Kimura, S1
Kong, CZ1
Noma, T1
Kohno, M1
Nishiyama, A1
Nakano, D1
Futai, R1
Ito, T1
Kawanishi, Y1
Terasaki, F1
Kitaura, Y1
Fogari, R1
Mugellini, A1
Destro, M1
Corradi, L1
Lazzari, P1
Zoppi, A1
Preti, P1
Derosa, G1
Szabolcsi, O1
Nagy-Toldi, A1
Zeher, M1
Végh, J1
Nagashima, A1
Watanabe, R1
Ogawa, M1
Suzuki, J1
Masumura, M1
Hishikari, K1
Shimizu, T1
Takayama, K1
Hirata, Y1
Nagai, R1
Isobe, M1
Matavelli, LC1
Siragy, HM1
Shibasaki, Y2
Nishiue, T2
Masaki, H2
Matsubara, H2
Iwasaka, T2
Tamura, K1
Matsumoto, N1
Mori, Y1
Nishikawa, M1
Veeraveedu, PT1
Watanabe, K1
Ma, M1
Gurusamy, N1
Palaniyandi, SS1
Wen, J1
Prakash, P1
Wahed, MI1
Kamal, FA1
Mito, S1
Kunisaki, M1
Kodama, M1
Aizawa, Y1
Hasegawa, K1
Wakino, S1
Tatematsu, S1
Yoshioka, K1
Homma, K1
Sugano, N1
Kimoto, M1
Hayashi, K1
Itoh, H1
Dahl, K1
Canetta, PA1
D'Agati, VD1
Radhakrishnan, J1
Bishop, JE1
Kiernan, LA1
Montgomery, HE1
Gohlke, P1
McEwan, JR1
Kyselovic, J1
Krenek, P1
Wibo, M1
Godfraind, T1

Trials

4 trials available for amlodipine and Cirrhosis

ArticleYear
Olmesartan ameliorates myocardial function independent of blood pressure control in patients with mild-to-moderate hypertension.
    Heart and vessels, 2009, Volume: 24, Issue:4

    Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Biomarkers; Blood Pressure; C-Reactive Pr

2009
Losartan and amlodipine on myocardial structure and function: a prospective, randomized, clinical trial.
    Diabetic medicine : a journal of the British Diabetic Association, 2012, Volume: 29, Issue:1

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Type 2; Diabetic Angiopathie

2012
[Angiotensin II type 1 antagonist suppress left ventricular hypertrophy and myocardial fibrosis in patient with end stage renal disease (ESRD)].
    Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60, Issue:10

    Topics: Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Calcium Chan

2002
Impact of the angiotensin II receptor antagonist, losartan, on myocardial fibrosis in patients with end-stage renal disease: assessment by ultrasonic integrated backscatter and biochemical markers.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2005, Volume: 28, Issue:10

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Collagen; Double-Blind Method; Echocardiography

2005

Other Studies

14 other studies available for amlodipine and Cirrhosis

ArticleYear
Effects of carvedilol or amlodipine on target organ damage in L-NAME hypertensive rats: their relationship with blood pressure variability.
    Journal of the American Society of Hypertension : JASH, 2017, Volume: 11, Issue:4

    Topics: Amlodipine; Animals; Antihypertensive Agents; Aorta; Biomarkers; Blood Pressure; Blood Pressure Dete

2017
Endothelial transcriptomics reveals activation of fibrosis-related pathways in hypertension.
    Physiological genomics, 2018, 02-01, Volume: 50, Issue:2

    Topics: Amlodipine; Animals; Blood Pressure; Calcium Channel Blockers; Disease Models, Animal; Fibrosis; Hea

2018
Effect of amlodipine on mouse renal interstitial fibrosis.
    European journal of pharmacology, 2016, Jun-05, Volume: 780

    Topics: Amlodipine; Animals; Calcium Channel Blockers; Fibrosis; Kidney; Macrophages; Mice; Phosphorylation;

2016
Role of the renin-angiotensin system in the pathogenesis of peritoneal fibrosis.
    Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis, 2008, Volume: 28 Suppl 3

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Dialysis Solu

2008
Additive beneficial effects of amlodipine and atorvastatin in reversing advanced cardiac hypertrophy in elderly spontaneously hypertensive rats.
    Clinical and experimental pharmacology & physiology, 2009, Volume: 36, Issue:11

    Topics: Aging; Amlodipine; Animals; Anticholesteremic Agents; Antihypertensive Agents; Atorvastatin; Cardiom

2009
Mineralocorticoid receptor blockade and calcium channel blockade have different renoprotective effects on glomerular and interstitial injury in rats.
    American journal of physiology. Renal physiology, 2009, Volume: 297, Issue:3

    Topics: Amlodipine; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cell Hypoxia

2009
[Systemic sclerosis in a patient suffering from breast cancer].
    Magyar onkologia, 2012, Volume: 56, Issue:1

    Topics: Adult; Amlodipine; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Duct

2012
Different roles of PPAR-γ activity on physiological and pathological alteration after myocardial ischemia.
    Journal of cardiovascular pharmacology, 2012, Volume: 60, Issue:2

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Anilides; Animals; Antihypertensive Agents; Ben

2012
Reduction of aldosterone production improves renal oxidative stress and fibrosis in diabetic rats.
    Journal of cardiovascular pharmacology, 2013, Volume: 61, Issue:1

    Topics: Aldosterone; Amides; Amlodipine; Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Cy

2013
Comparative effects of pranidipine with amlodipine in rats with heart failure.
    Pharmacology, 2006, Volume: 77, Issue:1

    Topics: Administration, Oral; Amlodipine; Animals; Atrial Natriuretic Factor; Blood Pressure; Calcium Channe

2006
Role of asymmetric dimethylarginine in vascular injury in transgenic mice overexpressing dimethylarginie dimethylaminohydrolase 2.
    Circulation research, 2007, Jul-20, Volume: 101, Issue:2

    Topics: Amidohydrolases; Amlodipine; Angiotensin II; Animals; Arginine; Blood Pressure; Coronary Circulation

2007
A 56-year-old woman with sarcoidosis and acute renal failure.
    Kidney international, 2008, Volume: 74, Issue:6

    Topics: Acute Kidney Injury; Amlodipine; Epoetin Alfa; Erythropoietin; Female; Fibrosis; Humans; Inflammatio

2008
Raised blood pressure, not renin-angiotensin systems, causes cardiac fibrosis in TGR m(Ren2)27 rats.
    Cardiovascular research, 2000, Volume: 47, Issue:1

    Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; Antihy

2000
Effects of amlodipine and lacidipine on cardiac remodelling and renin production in salt-loaded stroke-prone hypertensive rats.
    British journal of pharmacology, 2001, Volume: 134, Issue:7

    Topics: Actins; Amlodipine; Animals; Atrial Natriuretic Factor; Blood Pressure; Calcium Channel Blockers; Co

2001