amlodipine has been researched along with Cerebrovascular Disorders in 10 studies
Amlodipine: A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.
amlodipine : A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.
Cerebrovascular Disorders: A spectrum of pathological conditions of impaired blood flow in the brain. They can involve vessels (ARTERIES or VEINS) in the CEREBRUM, the CEREBELLUM, and the BRAIN STEM. Major categories include INTRACRANIAL ARTERIOVENOUS MALFORMATIONS; BRAIN ISCHEMIA; CEREBRAL HEMORRHAGE; and others.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Amlodipine orotate was prepared by reacting orotic acid and amlodipine to increase the dissolution rate at higher gastric pH conditions." | 5.33 | Effects of amlodipine orotate on hypertension-related complications in spontaneously hypertensive rats. ( Ahn, BO; Choi, SM; Kim, JE; Kwon, JW, 2006) |
| "The primary objective of this study was to determine whether combination therapy with valsartan 160 mg plus hydrochlorothiazide (HCTZ) 25 mg OD would be more effective than monotherapy with amlodipine 10 mg OD in reducing systolic blood pressure (SBP) in patients with moderate (stage II) hypertension and > or =1 other cardiovascular risk factor or concomitant condition." | 5.11 | Efficacy and tolerability of combination therapy with valsartan plus hydrochlorothiazide compared with amlodipine monotherapy in hypertensive patients with other cardiovascular risk factors: the VAST study. ( Bönner, G; Heintz, D; Kandra, A; Khder, Y; Malacco, E; Ruilope, LM, 2005) |
| " hypertension clinical trial databases for amlodipine (Norvasc) and nifedipine in the gastrointestinal therapeutic system (GITS) formulation (Procardia XL)." | 4.80 | Safety of long-acting dihydropyridine calcium channel blockers in hypertensive patients. ( Kloner, RA; Levenstein, M; Materson, BJ; Vetrovec, GW, 1998) |
| "This study aimed to evaluate the effect of 24 weeks of S-amlodipine besylate therapy on cognitive function in patients with hypertension and cerebrovascular disease." | 4.12 | Relationship Between Calcium Channel Blockers Therapy and Cognitive Function Improvement in Cognitive Decline Patients with Cerebrovascular Disease. ( Jeong, HT; Lee, JH; Park, KY; Sung, HH; Youn, YC, 2022) |
| "Amlodipine orotate was prepared by reacting orotic acid and amlodipine to increase the dissolution rate at higher gastric pH conditions." | 1.33 | Effects of amlodipine orotate on hypertension-related complications in spontaneously hypertensive rats. ( Ahn, BO; Choi, SM; Kim, JE; Kwon, JW, 2006) |
| "Amlodipine is a long-acting dihydropyridine calcium antagonist with vascular selectivity." | 1.28 | Vascular and myocardial effects of amlodipine: an overview. ( Gu, XH; Nayler, WG, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (50.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jeong, HT | 1 |
| Sung, HH | 1 |
| Lee, JH | 1 |
| Park, KY | 1 |
| Youn, YC | 1 |
| Takei, K | 1 |
| Araki, N | 1 |
| Ohkubo, T | 1 |
| Tamura, N | 1 |
| Yamamoto, T | 1 |
| Furuya, D | 1 |
| Yanagisawa, CT | 1 |
| Shimazu, K | 1 |
| Afanas'ev, IuI | 1 |
| Storozhenko, SIu | 1 |
| Grigorova, SIu | 1 |
| Ruilope, LM | 1 |
| Malacco, E | 1 |
| Khder, Y | 1 |
| Kandra, A | 1 |
| Bönner, G | 1 |
| Heintz, D | 1 |
| Choi, SM | 1 |
| Kim, JE | 1 |
| Ahn, BO | 1 |
| Kwon, JW | 1 |
| Sattar, MA | 1 |
| Johns, EJ | 1 |
| Suzuki, M | 1 |
| Yamanaka, K | 1 |
| Nabata, H | 1 |
| Tachibana, M | 1 |
| Kloner, RA | 1 |
| Vetrovec, GW | 1 |
| Materson, BJ | 1 |
| Levenstein, M | 1 |
| Nayler, WG | 2 |
| Gu, XH | 2 |
1 review available for amlodipine and Cerebrovascular Disorders
| Article | Year |
|---|---|
Safety of long-acting dihydropyridine calcium channel blockers in hypertensive patients.
Topics: Amlodipine; Calcium Channel Blockers; Cause of Death; Cerebrovascular Disorders; Clinical Trials as | 1998 |
2 trials available for amlodipine and Cerebrovascular Disorders
| Article | Year |
|---|---|
Comparison of the anti-hypertensive effects of the L/N-type calcium channel antagonist cilnidipine, and the L-type calcium channel antagonist amlodipine in hypertensive patients with cerebrovascular disease.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Calcium Channel | 2009 |
Efficacy and tolerability of combination therapy with valsartan plus hydrochlorothiazide compared with amlodipine monotherapy in hypertensive patients with other cardiovascular risk factors: the VAST study.
Topics: Age Factors; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Cerebrovascular Disorders; D | 2005 |
7 other studies available for amlodipine and Cerebrovascular Disorders
| Article | Year |
|---|---|
Relationship Between Calcium Channel Blockers Therapy and Cognitive Function Improvement in Cognitive Decline Patients with Cerebrovascular Disease.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cerebrovascular | 2022 |
[Potentialities of medicinal correction of cerebrovascular disturbances in patients with arterial hypertension].
Topics: Amlodipine; Antihypertensive Agents; Bisoprolol; Cerebrovascular Disorders; Drug Therapy, Combinatio | 2012 |
Effects of amlodipine orotate on hypertension-related complications in spontaneously hypertensive rats.
Topics: Amlodipine; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Calcium; Cardiomegaly; Ce | 2006 |
Evidence for an alpha 1-adrenoceptor subtype mediating adrenergic vasoconstriction in Wistar normotensive and stroke-prone spontaneously hypertensive rat kidney.
Topics: Adrenergic alpha-Antagonists; Amlodipine; Animals; Cerebrovascular Disorders; Clonidine; Dose-Respon | 1994 |
Long term effects of amlodipine on organ damage, stroke and life span in stroke prone spontaneously hypertensive rats.
Topics: Amlodipine; Animals; Cerebrovascular Disorders; Heart; Hypertension; Kidney; Longevity; Male; Myocar | 1993 |
Vascular and myocardial effects of amlodipine: an overview.
Topics: Amlodipine; Animals; Arteriosclerosis; Binding Sites; Calcium Channel Blockers; Cardiomegaly; Cerebr | 1991 |
Protecting the vasculature: an eye toward the future.
Topics: Amlodipine; Animals; Arteries; Arteriosclerosis; Blood Pressure; Calcium Channel Blockers; Cerebrova | 1990 |