Page last updated: 2024-10-22

amlodipine and Carotid Stenosis

amlodipine has been researched along with Carotid Stenosis in 5 studies

Amlodipine: A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.
amlodipine : A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.

Carotid Stenosis: Narrowing or stricture of any part of the CAROTID ARTERIES, most often due to atherosclerotic plaque formation. Ulcerations may form in atherosclerotic plaques and induce THROMBUS formation. Platelet or cholesterol emboli may arise from stenotic carotid lesions and induce a TRANSIENT ISCHEMIC ATTACK; CEREBROVASCULAR ACCIDENT; or temporary blindness (AMAUROSIS FUGAX). (From Adams et al., Principles of Neurology, 6th ed, pp 822-3)

Research Excerpts

ExcerptRelevanceReference
"Carotid endarterectomy and medical therapy (aspirin) were shown superior to medical therapy alone for asymptomatic (≥ 60%) carotid stenosis."5.20Optimal medical treatment versus carotid endarterectomy: the rationale and design of the Aggressive Medical Treatment Evaluation for Asymptomatic Carotid Artery Stenosis (AMTEC) study. ( Boytsov, S; Deev, A; Dupik, N; Kolos, I; Loukianov, M, 2015)
"Since previous studies have reported a beneficial effect of amlodipine and atorvastatin treatment in experimental atherosclerosis, we aimed to investigate the effect of the combination of both drugs on blood and plaque inflammation in patients with carotid stenosis."5.13Treatment with amlodipine and atorvastatin has additive effect on blood and plaque inflammation in hypertensive patients with carotid atherosclerosis. ( Blanco-Colio, LM; Egido, J; Madrigal-Matute, J; Martín-Conejero, A; Martín-Ventura, JL; Muñoz-Garcia, B; Ortega, L; Serrano, J; Vega, M, 2008)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's4 (80.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Calvet, D1
Amar, L1
Rossi, GP1
Laurent, S1
Dominiczak, AF1
Turc, G1
Barigou, M1
Jennings, G1
Guzik, T1
Touyz, RM1
Kolos, I1
Loukianov, M1
Dupik, N1
Boytsov, S1
Deev, A1
Martín-Ventura, JL1
Muñoz-Garcia, B1
Blanco-Colio, LM1
Martín-Conejero, A1
Madrigal-Matute, J1
Vega, M1
Ortega, L1
Serrano, J1
Egido, J1
Robaldo, A1
Rousas, N1
Pane, B1
Spinella, G1
Palombo, D1
Spence, JD1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Carotid Endarterectomy Versus Optimal Medical Treatment of Asymptomatic High Grade Carotid Artery Stenosis[NCT00805311]Phase 4400 participants (Actual)Interventional2009-04-30Terminated (stopped due to Due to the clear advantage of carotid endarterectomy)
Comparative Study Between Conventional and Telematic Follow-up of Patient Treated in a General Ang GI Surgery Department (TLM-CGD)[NCT03304509]200 participants (Actual)Interventional2017-03-19Completed
Telemedicine Follow-up for Routine, Low-Risk Oculoplastic Surgery[NCT04235803]100 participants (Anticipated)Interventional2021-07-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for amlodipine and Carotid Stenosis

ArticleYear
Optimal medical treatment versus carotid endarterectomy: the rationale and design of the Aggressive Medical Treatment Evaluation for Asymptomatic Carotid Artery Stenosis (AMTEC) study.
    International journal of stroke : official journal of the International Stroke Society, 2015, Volume: 10, Issue:2

    Topics: Amlodipine; Antihypertensive Agents; Aspirin; Carotid Stenosis; Combined Modality Therapy; Endartere

2015
Treatment with amlodipine and atorvastatin has additive effect on blood and plaque inflammation in hypertensive patients with carotid atherosclerosis.
    Kidney international. Supplement, 2008, Issue:111

    Topics: Aged; Amlodipine; Anticholesteremic Agents; Atorvastatin; Blood Pressure; Calcium Channel Blockers;

2008

Other Studies

3 other studies available for amlodipine and Carotid Stenosis

ArticleYear
Case of Asymptomatic Carotid Artery Stenosis in a Hypertensive Patient.
    Hypertension (Dallas, Tex. : 1979), 2017, Volume: 69, Issue:6

    Topics: Aged; Amlodipine; Antihypertensive Agents; Carotid Stenosis; Diuretics; Echocardiography, Doppler; H

2017
Telemedicine in vascular surgery: clinical experience in a single centre.
    Journal of telemedicine and telecare, 2010, Volume: 16, Issue:7

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Carotid Stenosis; Endart

2010
Telemedicine in vascular surgery: clinical experience in a single centre.
    Journal of telemedicine and telecare, 2010, Volume: 16, Issue:7

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Carotid Stenosis; Endart

2010
Telemedicine in vascular surgery: clinical experience in a single centre.
    Journal of telemedicine and telecare, 2010, Volume: 16, Issue:7

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Carotid Stenosis; Endart

2010
Telemedicine in vascular surgery: clinical experience in a single centre.
    Journal of telemedicine and telecare, 2010, Volume: 16, Issue:7

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Carotid Stenosis; Endart

2010
Asymptomatic carotid stenosis.
    Circulation, 2013, Feb-12, Volume: 127, Issue:6

    Topics: Aged; Amlodipine; Anticholesteremic Agents; Aspirin; Asymptomatic Diseases; Atorvastatin; Azetidines

2013