amlodipine has been researched along with Cardiotoxicity in 5 studies
Amlodipine: A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.
amlodipine : A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.
Cardiotoxicity: Damage to the HEART or its function secondary to exposure to toxic substances such as drugs used in CHEMOTHERAPY; IMMUNOTHERAPY; or RADIATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Amlodipine overdoses have significant cardiac toxicity and are difficult to treat." | 4.02 | Efficacy of methylene blue in a murine model of amlodipine overdose. ( Baccanale, CL; de Castro Brás, LE; Eccleston, L; Meggs, WJ; O'Rourke, D; Pittman, P; Sloan, T; St Antoine, JC; Verzwyvelt, SM, 2021) |
| " We administered this solution to three animals in order to determine a toxic dose, capable of facilitating a two-arm study of amlodipine toxicity." | 1.56 | Development and Feasibility of a Porcine Model of Amlodipine Toxicity. ( Boley, SP; Engebretsen, KM; LeRoy, JM; Mackenzie, RB; Stellpflug, SJ, 2020) |
| "Three hours after admission cardiac arrest happened and cardiopulmonary resuscitation was unsuccessful." | 1.43 | Failure of intravenous lipid emulsion in treatment of cardiotoxicity caused by mixed overdose including dihydropyridine calcium channel blockers. ( Brajković, G; Djordjević, S; Jović-Stosić, J; Mladenov, M; Putić, V; Zivanović, D, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 3 (60.00) | 2.80 |
| Authors | Studies |
|---|---|
| LeRoy, JM | 2 |
| Boley, SP | 2 |
| Corcoran, JN | 1 |
| Engebretsen, KM | 2 |
| Stellpflug, SJ | 2 |
| de Castro Brás, LE | 1 |
| Baccanale, CL | 1 |
| Eccleston, L | 1 |
| Sloan, T | 1 |
| St Antoine, JC | 1 |
| Verzwyvelt, SM | 1 |
| Pittman, P | 1 |
| O'Rourke, D | 1 |
| Meggs, WJ | 1 |
| Higa, A | 1 |
| Hoshi, H | 1 |
| Yanagisawa, Y | 1 |
| Ito, E | 1 |
| Morisawa, G | 1 |
| Imai, JI | 1 |
| Watanabe, S | 1 |
| Takagi, M | 1 |
| Mackenzie, RB | 1 |
| Jović-Stosić, J | 1 |
| Putić, V | 1 |
| Zivanović, D | 1 |
| Mladenov, M | 1 |
| Brajković, G | 1 |
| Djordjević, S | 1 |
5 other studies available for amlodipine and Cardiotoxicity
| Article | Year |
|---|---|
Effect of Methylene Blue on a Porcine Model of Amlodipine Toxicity.
Topics: Amlodipine; Animals; Antidotes; Cardiotoxicity; Cardiovascular Diseases; Cardiovascular System; Dise | 2020 |
Efficacy of methylene blue in a murine model of amlodipine overdose.
Topics: Amlodipine; Animals; Cardiotoxicity; Disease Models, Animal; Drug Overdose; Methylene Blue; Mice; Mi | 2021 |
Evaluation system for arrhythmogenic potential of drugs using human-induced pluripotent stem cell-derived cardiomyocytes and gene expression analysis.
Topics: Amlodipine; Arrhythmias, Cardiac; Benzimidazoles; Biphenyl Compounds; Bisoprolol; Cardiotoxicity; Ce | 2017 |
Development and Feasibility of a Porcine Model of Amlodipine Toxicity.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Cardiotoxicity; Disease Models, Animal; Feasibility S | 2020 |
Failure of intravenous lipid emulsion in treatment of cardiotoxicity caused by mixed overdose including dihydropyridine calcium channel blockers.
Topics: Adult; Amlodipine; Calcium Channel Blockers; Cardiotoxicity; Dihydropyridines; Emergencies; Fat Emul | 2016 |