amlodipine has been researched along with Brain Ischemia in 6 studies
Amlodipine: A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.
amlodipine : A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to compare the efficacy and safety of lercanidipine and amlodipine in the treatment of hypertensive patients with acute cerebral ischemic stroke." | 9.20 | Effects of lercanidipine versus amlodipine in hypertensive patients with cerebral ischemic stroke. ( Cao, TS; Huynh, VM; Tran, VH, 2015) |
| "This study investigated the effects of amlodipine, an L-type calcium channel blocker, on stroke size after focal brain ischemia in apolipoprotein E-deficient (ApoE KO) mice." | 7.73 | Amlodipine treatment reduces stroke size in apolipoprotein E-deficient mice. ( Chen, R; Horiuchi, M; Ide, A; Iwai, M; Iwanami, J; Mogi, M; Tsukuda, K; Yoshii, T, 2006) |
| "Ischemic stroke is a major neurologic disorder and a leading cause of disability and death in the world." | 5.37 | Protection against ischemic stroke damage by synergistic treatment with amlodipine plus atorvastatin in Zucker metabolic rat. ( Abe, K; Deguchi, K; Deguchi, S; Ikeda, Y; Kawai, H; Kurata, T; Matsuura, T; Ohta, Y; Omote, Y; Yamashita, T, 2011) |
| "The aim of this study was to compare the efficacy and safety of lercanidipine and amlodipine in the treatment of hypertensive patients with acute cerebral ischemic stroke." | 5.20 | Effects of lercanidipine versus amlodipine in hypertensive patients with cerebral ischemic stroke. ( Cao, TS; Huynh, VM; Tran, VH, 2015) |
| "In patients with hypertension and dementia, nifedipine was associated with increased mortality risk (aHR 1." | 4.02 | Calcium channel blockers, survival and ischaemic stroke in patients with dementia: a Swedish registry study. ( Eriksdotter, M; Garcia-Ptacek, S; Kalar, I; Kramberger, MG; Schwertner, E; Secnik, J; von Euler, M; Winblad, B; Xu, H, 2021) |
| "This study investigated the effects of amlodipine, an L-type calcium channel blocker, on stroke size after focal brain ischemia in apolipoprotein E-deficient (ApoE KO) mice." | 3.73 | Amlodipine treatment reduces stroke size in apolipoprotein E-deficient mice. ( Chen, R; Horiuchi, M; Ide, A; Iwai, M; Iwanami, J; Mogi, M; Tsukuda, K; Yoshii, T, 2006) |
| "Vascular dementia is the second most common cause of dementia affecting over seven million people worldwide, yet there are no licensed treatments." | 2.82 | A randomised controlled trial of calcium channel blockade (CCB) with Amlodipine For the treatment oF subcortical ischaEmic vasCular demenTia (AFFECT): study protocol. ( Arrojo, F; Ballard, C; Bath, P; Canning, R; Connelly, P; Corbett, A; Coulthard, E; Greenan, C; Henderson, C; Holmes, C; Jones, R; Kehoe, PG; Knapp, M; McGuinness, B; Murphy, L; O'Sullivan, M; Passmore, P; Stewart, R; Thomas, A; Wallach, S; Yu, LM, 2016) |
| "Ischemic stroke is a major neurologic disorder and a leading cause of disability and death in the world." | 1.37 | Protection against ischemic stroke damage by synergistic treatment with amlodipine plus atorvastatin in Zucker metabolic rat. ( Abe, K; Deguchi, K; Deguchi, S; Ikeda, Y; Kawai, H; Kurata, T; Matsuura, T; Ohta, Y; Omote, Y; Yamashita, T, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Kalar, I | 1 |
| Xu, H | 1 |
| Secnik, J | 1 |
| Schwertner, E | 1 |
| Kramberger, MG | 1 |
| Winblad, B | 1 |
| von Euler, M | 1 |
| Eriksdotter, M | 1 |
| Garcia-Ptacek, S | 1 |
| Gan'shina, TS | 1 |
| Kim, GA | 1 |
| Gnezdilova, AV | 1 |
| Kurdiumov, IN | 1 |
| Mirzoian, RS | 1 |
| Cao, TS | 1 |
| Huynh, VM | 1 |
| Tran, VH | 1 |
| Greenan, C | 1 |
| Murphy, L | 1 |
| Yu, LM | 1 |
| Kehoe, PG | 1 |
| Coulthard, E | 1 |
| Bath, P | 1 |
| Stewart, R | 1 |
| Jones, R | 1 |
| Corbett, A | 1 |
| Thomas, A | 1 |
| Connelly, P | 1 |
| Arrojo, F | 1 |
| Canning, R | 1 |
| Wallach, S | 1 |
| Henderson, C | 1 |
| McGuinness, B | 1 |
| O'Sullivan, M | 1 |
| Holmes, C | 1 |
| Knapp, M | 1 |
| Ballard, C | 1 |
| Passmore, P | 1 |
| Kawai, H | 1 |
| Deguchi, S | 1 |
| Deguchi, K | 1 |
| Yamashita, T | 1 |
| Ohta, Y | 1 |
| Omote, Y | 1 |
| Kurata, T | 1 |
| Ikeda, Y | 1 |
| Matsuura, T | 1 |
| Abe, K | 1 |
| Mogi, M | 1 |
| Iwai, M | 1 |
| Chen, R | 1 |
| Iwanami, J | 1 |
| Ide, A | 1 |
| Tsukuda, K | 1 |
| Yoshii, T | 1 |
| Horiuchi, M | 1 |
2 trials available for amlodipine and Brain Ischemia
| Article | Year |
|---|---|
Effects of lercanidipine versus amlodipine in hypertensive patients with cerebral ischemic stroke.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Brain Ischemia; Di | 2015 |
A randomised controlled trial of calcium channel blockade (CCB) with Amlodipine For the treatment oF subcortical ischaEmic vasCular demenTia (AFFECT): study protocol.
Topics: Activities of Daily Living; Amlodipine; Brain Ischemia; Calcium Channel Blockers; Clinical Protocols | 2016 |
4 other studies available for amlodipine and Brain Ischemia
| Article | Year |
|---|---|
Calcium channel blockers, survival and ischaemic stroke in patients with dementia: a Swedish registry study.
Topics: Alzheimer Disease; Amlodipine; Brain Ischemia; Calcium Channel Blockers; Humans; Hypertension; Ische | 2021 |
[Effect of S-amlodipine nicotinate on the cerebral circulation in rats under conditions of ischemic and hemorrhagic brain injury].
Topics: Amlodipine; Animals; Animals, Outbred Strains; Brain; Brain Edema; Brain Injuries; Brain Ischemia; L | 2014 |
Protection against ischemic stroke damage by synergistic treatment with amlodipine plus atorvastatin in Zucker metabolic rat.
Topics: Amlodipine; Animals; Atorvastatin; Brain Ischemia; Calcium Channel Blockers; Disease Models, Animal; | 2011 |
Amlodipine treatment reduces stroke size in apolipoprotein E-deficient mice.
Topics: Amlodipine; Animals; Apolipoproteins E; Brain Ischemia; Calcium Channel Blockers; Cerebrovascular Ci | 2006 |