amlodipine has been researched along with Brain Edema in 4 studies
Amlodipine: A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.
amlodipine : A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.
Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Oral treatment with amlodipine (n=7), initiated at day 0, reduced systolic blood pressure, reversed cerebral edema and restored blood-brain barrier integrity." | 5.31 | Reduction of cerebral injury in stroke-prone spontaneously hypertensive rats by amlodipine. ( Blezer, E; Goldschmeding, R; Joles, J; Koomans, H; Nicolay, K, 2002) |
| " L/N-type Ca(2+) channel blocker cilnidipine could reduce the size of cerebral infarction in the rat focal brain ischemia." | 4.86 | [Calcium antagonists: current and future applications based on new evidence. Neuroprotective effect of calcium antagonists]. ( Araki, N; Ito, Y, 2010) |
| " Treatment with azelnidipine and amlodipine reduced infarct volume and brain edema." | 3.74 | Prevention of neuronal damage by calcium channel blockers with antioxidative effects after transient focal ischemia in rats. ( Abe, K; Deguchi, K; Hayashi, T; Kamiya, T; Lukic-Panin, V; Sehara, Y; Tsuchiya, A; Yamashita, T; Zhang, H, 2007) |
| "Oral treatment with amlodipine (n=7), initiated at day 0, reduced systolic blood pressure, reversed cerebral edema and restored blood-brain barrier integrity." | 1.31 | Reduction of cerebral injury in stroke-prone spontaneously hypertensive rats by amlodipine. ( Blezer, E; Goldschmeding, R; Joles, J; Koomans, H; Nicolay, K, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gan'shina, TS | 1 |
| Kim, GA | 1 |
| Gnezdilova, AV | 1 |
| Kurdiumov, IN | 1 |
| Mirzoian, RS | 1 |
| Ito, Y | 1 |
| Araki, N | 1 |
| Blezer, E | 1 |
| Nicolay, K | 1 |
| Goldschmeding, R | 1 |
| Koomans, H | 1 |
| Joles, J | 1 |
| Lukic-Panin, V | 1 |
| Kamiya, T | 1 |
| Zhang, H | 1 |
| Hayashi, T | 1 |
| Tsuchiya, A | 1 |
| Sehara, Y | 1 |
| Deguchi, K | 1 |
| Yamashita, T | 1 |
| Abe, K | 1 |
1 review available for amlodipine and Brain Edema
| Article | Year |
|---|---|
[Calcium antagonists: current and future applications based on new evidence. Neuroprotective effect of calcium antagonists].
Topics: Amlodipine; Animals; Brain Edema; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channe | 2010 |
3 other studies available for amlodipine and Brain Edema
| Article | Year |
|---|---|
[Effect of S-amlodipine nicotinate on the cerebral circulation in rats under conditions of ischemic and hemorrhagic brain injury].
Topics: Amlodipine; Animals; Animals, Outbred Strains; Brain; Brain Edema; Brain Injuries; Brain Ischemia; L | 2014 |
Reduction of cerebral injury in stroke-prone spontaneously hypertensive rats by amlodipine.
Topics: Amlodipine; Animals; Antihypertensive Agents; Blood Pressure; Brain Edema; Hypertension; Male; Rats; | 2002 |
Prevention of neuronal damage by calcium channel blockers with antioxidative effects after transient focal ischemia in rats.
Topics: Amlodipine; Animals; Antioxidants; Apoptosis; Azetidinecarboxylic Acid; Brain; Brain Edema; Brain In | 2007 |