amlodipine has been researched along with Autoimmune Diabetes in 7 studies
Amlodipine: A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.
amlodipine : A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Diabetic retinopathy is characterized by morphological changes in the retina secondary to disturbances in retinal blood flow." | 6.76 | Lack of effect of short-term treatment with amlodipine and lisinopril on retinal autoregulation in normotensive patients with type 1 diabetes and mild diabetic retinopathy. ( Bek, T; Erlandsen, M; Jeppesen, P; Mehlsen, J; Poulsen, PL, 2011) |
| "SEVERAL MECHANISMS: The progression in renal failure first implies hemodynamic mechanisms and among which angiotensin II has a central role, but also an increase in proteinuria and the induction of many inflammatory and mitogenic mediators that enhance fibrosis (TGF-beta), an effect stimulating the thrombotic mechanism." | 4.81 | [The effect of angiotensin-converting enzyme inhibitors on the progression of chronic renal failure]. ( Bernadet-Monrozies, P; Durand, D; Kamar, N; Rostaing, L, 2002) |
| "Diabetic retinopathy is characterized by morphological changes in the retina secondary to disturbances in retinal blood flow." | 2.76 | Lack of effect of short-term treatment with amlodipine and lisinopril on retinal autoregulation in normotensive patients with type 1 diabetes and mild diabetic retinopathy. ( Bek, T; Erlandsen, M; Jeppesen, P; Mehlsen, J; Poulsen, PL, 2011) |
| "Aliskiren was then force-titrated to 300 mg once daily for another 6 weeks." | 2.76 | Aliskiren as add-on therapy in the treatment of hypertensive diabetic patients inadequately controlled with valsartan/HCT combination: a placebo-controlled study. ( Baek, I; Drummond, W; Keefe, DL; Ramos, E; Sirenko, YM, 2011) |
| "Twenty-eight patients who had type 1 diabetes and known diabetic renal disease and had a persistently elevated albumin creatinine ratio (ACR) > 10 mg/mmol despite office BP recordings < or = 140/80 mmHg on maximal recommended dose of the ACEI lisinopril were studied." | 2.71 | Targeting albumin excretion rate in the treatment of the hypertensive diabetic patient with renal disease. ( Bilous, R; Karalliedde, J; Krimholtz, MJ; Thomas, S; Viberti, G, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sweiss, N | 1 |
| Sharma, K | 1 |
| Mehlsen, J | 1 |
| Jeppesen, P | 1 |
| Erlandsen, M | 1 |
| Poulsen, PL | 1 |
| Bek, T | 1 |
| Drummond, W | 1 |
| Sirenko, YM | 1 |
| Ramos, E | 1 |
| Baek, I | 1 |
| Keefe, DL | 1 |
| Bernadet-Monrozies, P | 1 |
| Rostaing, L | 1 |
| Kamar, N | 1 |
| Durand, D | 1 |
| Krimholtz, MJ | 1 |
| Karalliedde, J | 1 |
| Thomas, S | 1 |
| Bilous, R | 1 |
| Viberti, G | 1 |
| de Cavanagh, EM | 1 |
| Ferder, L | 1 |
| Toblli, JE | 1 |
| Piotrkowski, B | 1 |
| Stella, I | 1 |
| Fraga, CG | 1 |
| Inserra, F | 1 |
| Pernu, HE | 1 |
| Knuuttila, ML | 1 |
| Huttunen, KR | 1 |
| Tiilikainen, AS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A 12-week, Randomized, Double-blind, Placebo Controlled, Parallel Group Study Evaluating the Efficacy & Safety of Aliskiren in Patients With Diabetes & Hypertension Not Adequately Responsive to the Combination of Valsartan 160 mg & Hydrochlorothiazide 25 [NCT00219102] | Phase 3 | 336 participants | Interventional | 2005-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for amlodipine and Autoimmune Diabetes
| Article | Year |
|---|---|
Adiponectin effects on the kidney.
Topics: Adiponectin; Albuminuria; Amlodipine; AMP-Activated Protein Kinases; Animals; Benzimidazoles; Benzoa | 2014 |
[The effect of angiotensin-converting enzyme inhibitors on the progression of chronic renal failure].
Topics: Amlodipine; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibito | 2002 |
3 trials available for amlodipine and Autoimmune Diabetes
| Article | Year |
|---|---|
Lack of effect of short-term treatment with amlodipine and lisinopril on retinal autoregulation in normotensive patients with type 1 diabetes and mild diabetic retinopathy.
Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Flow Velocity; Blood Pressure; Cross-Over Studies; | 2011 |
Aliskiren as add-on therapy in the treatment of hypertensive diabetic patients inadequately controlled with valsartan/HCT combination: a placebo-controlled study.
Topics: Aged; Amides; Amlodipine; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Type 1; Diabet | 2011 |
Targeting albumin excretion rate in the treatment of the hypertensive diabetic patient with renal disease.
Topics: Adult; Aged; Albuminuria; Amlodipine; Benzimidazoles; Biphenyl Compounds; Cross-Over Studies; Diabet | 2005 |
2 other studies available for amlodipine and Autoimmune Diabetes
| Article | Year |
|---|---|
Renal mitochondrial impairment is attenuated by AT1 blockade in experimental Type I diabetes.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Antioxidants; | 2008 |
Drug-induced gingival overgrowth and class II major histocompatibility antigens.
Topics: Adult; Amlodipine; Azathioprine; Cyclosporine; Diabetes Mellitus, Type 1; Felodipine; Female; Gingiv | 1994 |