Page last updated: 2024-10-22

amlodipine and Arteriosclerosis, Coronary

amlodipine has been researched along with Arteriosclerosis, Coronary in 59 studies

Amlodipine: A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.
amlodipine : A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.

Research Excerpts

ExcerptRelevanceReference
"The aim of the study was to evaluate the efficacy and safety of fixed-dose combination (FDC) of metoprolol, telmisartan, and chlorthalidone in patients with essential hypertension and stable coronary artery disease (CAD) who showed inadequate response to dual therapy."9.51Fixed-dose Combination of Metoprolol, Telmisartan, and Chlorthalidone for Essential Hypertension in Adults with Stable Coronary Artery Disease: Phase III Study. ( Agrawal, S; Anand, J; Bachani, D; Doshi, M; Gaikwad, VB; Halder, SK; Kinholkar, B; Kumar, DA; Kumbhar, A; Mathur, R; Mehta, S; Sarkar, G; Sharma, A, 2022)
"Long-term therapy with a combination of perindopril and amlodipine has shown a beneficial effect on the morbidity and mortality of patients with stable coronary artery disease (SCAD) and hypertension."9.22Short-Term Cardioprotective Effects of the Original Perindopril/Amlodipine Fixed-Dose Combination in Patients with Stable Coronary Artery Disease: Results of the PAPA-CAD Study. ( Dézsi, CA; Forster, T, 2016)
"Amlodipine, commonly used for relief of ischemic symptoms in coronary artery disease (CAD), may affect clopidogrel-induced antiplatelet effects."9.20Comparison of the pharmacodynamic effects of ranolazine versus amlodipine on platelet reactivity in stable patients with coronary artery disease treated with dual antiplatelet therapy : The ROMAN (RanOlazine vs. aMlodipine on platelet reactivity in stable ( Angiolillo, DJ; Gaudio, C; Greco, C; Marazzi, G; Pelliccia, F; Rollini, F; Rosano, G; Vitale, C, 2015)
"Combination therapy with benazepril 40 mg and amlodipine 10 mg (B+A) has been shown to be more effective than benazepril 40 mg and hydrochlorothiazide (HCTZ) 25 mg (B+H) in reducing cardiovascular (CV) events in high-risk patients with stage 2 hypertension with similar blood pressure reductions."9.17Comparison of benazepril plus amlodipine or hydrochlorothiazide in high-risk patients with hypertension and coronary artery disease. ( Bakris, G; Briasoulis, A; Dahlof, B; Hester, A; Hua, T; Jamerson, K; Kelly, RY; Pitt, B; Weber, MA; Zappe, D, 2013)
"The purpose of this post hoc subgroup analysis was to compare the incidence of major adverse cardiovascular events (MACE) of patients treated with candesartan and amlodipine with that of those with candesartan and non-amlodipine CCBs in hypertensive patients with coronary artery disease (CAD)."9.17Efficacy of the combination of amlodipine and candesartan in hypertensive patients with coronary artery disease: a subanalysis of the HIJ-CREATE study. ( Hagiwara, N; Haruta, S; Kawada-Watanabe, E; Koyanagi, R; Ogawa, H; Takagi, A; Yamaguchi, J, 2013)
"In many countries, combination therapy with amlodipine and atorvastatin is indicated for the treatment of patients with hypertension and hypercholesterolemia."9.15Impact of combination therapy with amlodipine and atorvastatin on plasma adiponectin levels in hypertensive patients with coronary artery disease: combination therapy and adiponectin. ( Cheung, BM; Lam, KS; Li, M; Tse, HF; Xu, A, 2011)
"To estimate the potential savings in overall cardiovascular disease (CVD) treatment costs for the US population with coronary artery disease (CAD) resulting from the use of amlodipine."9.10Economic benefits of amlodipine treatment in patients with coronary artery disease. ( Arikian, S; Arocho, R; Casciano, J; Casciano, R; Chen, J; Doyle, JJ; Kugel, H, 2002)
"A literature search was performed in PubMed/MEDLINE to identify articles published in English between 1988 and March 2008 describing clinical trials, particularly outcome trials, or mechanisms of therapeutic action relevant to the use of combination therapy in patients with hypertension or stable coronary artery disease with an ACE inhibitor (perindopril) and a calcium channel blocker (amlodipine)."8.84Optimizing the treatment of hypertension and stable coronary artery disease: clinical evidence for fixed-combination perindopril/amlodipine. ( Ferrari, R, 2008)
"In the present quantitative overview of outcome trials, we investigated the efficacy of amlodipine or angiotensin receptor blockers in the prevention of stroke and myocardial infarction in patients with hypertension, coronary artery disease, or diabetic nephropathy."8.84Prevention of stroke and myocardial infarction by amlodipine and Angiotensin receptor blockers: a quantitative overview. ( Franklin, SS; Li, Y; Safar, M; Wang, JG, 2007)
"to compare the antianginal and pulse slowing effects, the impact on the ectopic myocardial activity as well as the safety of the treatment with beta - adrenoblocker bisoprolol, calcium antagonist verapamil and the combination of bisoprolol with amlodipine in patients with stable angina (SA) and bronchial asthma (BA)."7.91[Possibilities of cardioselective beta - blocker bisoprolol therapy in patients having coronary artery disease and bronchial asthma]. ( Grigorieva, NY; Ilyushina, TP; Yashina, EM, 2019)
"This study assessed adherence to and the safety, tolerance, and effectiveness of the perindopril/amlodipine FDC in Greek patients with hypertension and stable coronary artery disease (CAD) over a 4-month period."7.85Adherence to Treatment, Safety, Tolerance, and Effectiveness of Perindopril/Amlodipine Fixed-Dose Combination in Greek Patients with Hypertension and Stable Coronary Artery Disease: A Pan-Hellenic Prospective Observational Study of Daily Clinical Practice ( Kotsis, VT; Liakos, CI; Papadopoulos, DP, 2017)
"The objective of this analysis was to calculate the cost-effectiveness of amlodipine therapy in patients with coronary artery disease in Sweden."7.71A cost-effectiveness evaluation of amlodipine usage in patients with coronary artery disease in Sweden. ( Arikian, S; Arocho, R; Casciano, J; Casciano, R; Doyle, JJ; Kim, R; Kugel, H; McGuire, A; Svangren, P, 2002)
"The aim of the study was to evaluate the efficacy and safety of fixed-dose combination (FDC) of metoprolol, telmisartan, and chlorthalidone in patients with essential hypertension and stable coronary artery disease (CAD) who showed inadequate response to dual therapy."5.51Fixed-dose Combination of Metoprolol, Telmisartan, and Chlorthalidone for Essential Hypertension in Adults with Stable Coronary Artery Disease: Phase III Study. ( Agrawal, S; Anand, J; Bachani, D; Doshi, M; Gaikwad, VB; Halder, SK; Kinholkar, B; Kumar, DA; Kumbhar, A; Mathur, R; Mehta, S; Sarkar, G; Sharma, A, 2022)
"Long-term therapy with a combination of perindopril and amlodipine has shown a beneficial effect on the morbidity and mortality of patients with stable coronary artery disease (SCAD) and hypertension."5.22Short-Term Cardioprotective Effects of the Original Perindopril/Amlodipine Fixed-Dose Combination in Patients with Stable Coronary Artery Disease: Results of the PAPA-CAD Study. ( Dézsi, CA; Forster, T, 2016)
"Amlodipine, commonly used for relief of ischemic symptoms in coronary artery disease (CAD), may affect clopidogrel-induced antiplatelet effects."5.20Comparison of the pharmacodynamic effects of ranolazine versus amlodipine on platelet reactivity in stable patients with coronary artery disease treated with dual antiplatelet therapy : The ROMAN (RanOlazine vs. aMlodipine on platelet reactivity in stable ( Angiolillo, DJ; Gaudio, C; Greco, C; Marazzi, G; Pelliccia, F; Rollini, F; Rosano, G; Vitale, C, 2015)
"Combination therapy with benazepril 40 mg and amlodipine 10 mg (B+A) has been shown to be more effective than benazepril 40 mg and hydrochlorothiazide (HCTZ) 25 mg (B+H) in reducing cardiovascular (CV) events in high-risk patients with stage 2 hypertension with similar blood pressure reductions."5.17Comparison of benazepril plus amlodipine or hydrochlorothiazide in high-risk patients with hypertension and coronary artery disease. ( Bakris, G; Briasoulis, A; Dahlof, B; Hester, A; Hua, T; Jamerson, K; Kelly, RY; Pitt, B; Weber, MA; Zappe, D, 2013)
"Treatment with either aliskiren or amlodipine did not significantly alter surrogate biomarkers of atherosclerosis in patients with both diabetes and established cardiovascular disease already receiving appropriate secondary cardiovascular prevention therapy."5.17Effects of direct renin inhibition on atherosclerotic biomarkers in patients with stable coronary artery disease and type 2 diabetes mellitus. ( Abo-Salem, E; Doctolero, S; Irons, BK; Meyerrose, GE; Seifert, CF; Simoni, JS; Trujillo, A, 2013)
"The purpose of this post hoc subgroup analysis was to compare the incidence of major adverse cardiovascular events (MACE) of patients treated with candesartan and amlodipine with that of those with candesartan and non-amlodipine CCBs in hypertensive patients with coronary artery disease (CAD)."5.17Efficacy of the combination of amlodipine and candesartan in hypertensive patients with coronary artery disease: a subanalysis of the HIJ-CREATE study. ( Hagiwara, N; Haruta, S; Kawada-Watanabe, E; Koyanagi, R; Ogawa, H; Takagi, A; Yamaguchi, J, 2013)
"The study was a randomized controlled trial of 2 antihypertensives (amlodipine and enalapril) compared with placebo in patients with coronary artery disease and diastolic blood pressure less than 100 mm Hg."5.16Relationship of antihypertensive treatment to plasma markers of vascular inflammation and remodeling in the Comparison of Amlodipine versus Enalapril to Limit Occurrences of Thrombosis study. ( Ganz, P; Kinlay, S; Libby, P; Nicholls, SJ; Nissen, SE; Rifai, N; Sutradhar, SC; Zamani, P, 2012)
"A previous study reported that amlodipine retarded coronary plaque progression in patients with coronary artery disease."5.15Azelnidipine and amlodipine anti-coronary atherosclerosis trial in hypertensive patients undergoing coronary intervention by serial volumetric intravascular ultrasound analysis in Juntendo University (ALPS-J). ( Daida, H; Fujiwara, Y; Hiro, T; Inoue, K; Kawamura, M; Kojima, T; Komiyama, N; Kurata, T; Miyauchi, K; Nakazato, Y; Okazaki, S; Sumiyoshi, M; Suwa, S; Tamura, H; Tanimoto, K; Yamagami, S; Yokoyama, K; Yokoyama, T, 2011)
"In many countries, combination therapy with amlodipine and atorvastatin is indicated for the treatment of patients with hypertension and hypercholesterolemia."5.15Impact of combination therapy with amlodipine and atorvastatin on plasma adiponectin levels in hypertensive patients with coronary artery disease: combination therapy and adiponectin. ( Cheung, BM; Lam, KS; Li, M; Tse, HF; Xu, A, 2011)
"To estimate the potential savings in overall cardiovascular disease (CVD) treatment costs for the US population with coronary artery disease (CAD) resulting from the use of amlodipine."5.10Economic benefits of amlodipine treatment in patients with coronary artery disease. ( Arikian, S; Arocho, R; Casciano, J; Casciano, R; Chen, J; Doyle, JJ; Kugel, H, 2002)
"The Coronary AngioPlasty Amlodipine REStenosis Study (CAPARES) is a multicentre, double-blind, placebo controlled restenosis trial investigating the effect of amlodipine on angiographic and clinical endpoints in patients undergoing routine percutaneous transluminal coronary angioplasty (PTCA) for stable angina pectoris."5.09Results and clinical implications of the CAPARES trial. ( Jorgensen, B; Thaulow, E, 2000)
"The Prospective Randomized Evaluation of the Vascular Effects of Norvasc Trial (PREVENT) was a multicenter, randomized, placebo-controlled, double-masked clinical trial designed to test whether amlodipine would slow the progression of early coronary atherosclerosis in 825 patients with angiographically documented coronary artery disease."5.09Effect of amlodipine on the progression of atherosclerosis and the occurrence of clinical events. PREVENT Investigators. ( Byington, RP; Furberg, CD; Hunninghake, DB; Mancini, GB; Miller, ME; Pitt, B; Riley, W, 2000)
"To review the pharmacoeconomic impact of the use of amlodipine in coronary artery disease (CAD) patients."4.85Amlodipine: a pharmacoeconomic review. ( de Portu, S; Mantovani, LG, 2009)
"A literature search was performed in PubMed/MEDLINE to identify articles published in English between 1988 and March 2008 describing clinical trials, particularly outcome trials, or mechanisms of therapeutic action relevant to the use of combination therapy in patients with hypertension or stable coronary artery disease with an ACE inhibitor (perindopril) and a calcium channel blocker (amlodipine)."4.84Optimizing the treatment of hypertension and stable coronary artery disease: clinical evidence for fixed-combination perindopril/amlodipine. ( Ferrari, R, 2008)
"In the present quantitative overview of outcome trials, we investigated the efficacy of amlodipine or angiotensin receptor blockers in the prevention of stroke and myocardial infarction in patients with hypertension, coronary artery disease, or diabetic nephropathy."4.84Prevention of stroke and myocardial infarction by amlodipine and Angiotensin receptor blockers: a quantitative overview. ( Franklin, SS; Li, Y; Safar, M; Wang, JG, 2007)
"to compare the antianginal and pulse slowing effects, the impact on the ectopic myocardial activity as well as the safety of the treatment with beta - adrenoblocker bisoprolol, calcium antagonist verapamil and the combination of bisoprolol with amlodipine in patients with stable angina (SA) and bronchial asthma (BA)."3.91[Possibilities of cardioselective beta - blocker bisoprolol therapy in patients having coronary artery disease and bronchial asthma]. ( Grigorieva, NY; Ilyushina, TP; Yashina, EM, 2019)
"This study assessed adherence to and the safety, tolerance, and effectiveness of the perindopril/amlodipine FDC in Greek patients with hypertension and stable coronary artery disease (CAD) over a 4-month period."3.85Adherence to Treatment, Safety, Tolerance, and Effectiveness of Perindopril/Amlodipine Fixed-Dose Combination in Greek Patients with Hypertension and Stable Coronary Artery Disease: A Pan-Hellenic Prospective Observational Study of Daily Clinical Practice ( Kotsis, VT; Liakos, CI; Papadopoulos, DP, 2017)
"The objective of this analysis was to calculate the cost-effectiveness of amlodipine therapy in patients with coronary artery disease in Sweden."3.71A cost-effectiveness evaluation of amlodipine usage in patients with coronary artery disease in Sweden. ( Arikian, S; Arocho, R; Casciano, J; Casciano, R; Doyle, JJ; Kim, R; Kugel, H; McGuire, A; Svangren, P, 2002)
" In the prospective Valsartan Antihypertensive Long-term Use Evaluation (VALUE) trial, patients were randomized to valsartan or amlodipine regimens and followed for 4."2.82No evidence for a J-shaped curve in treated hypertensive patients with increased cardiovascular risk: The VALUE trial. ( Bangalore, S; Berge, E; Holzhauer, B; Hua, TA; Julius, S; Kjeldsen, SE; Mancia, G; Messerli, FH; Weber, MA; Zanchetti, A; Zappe, D, 2016)
"Amlodipine was associated with a mean blood pressure reduction of 8/3 mm Hg (P<0."2.73Modulation of arterial reactivity using amlodipine and atorvastatin measured by ultrasound examination (MARGAUX). ( Anderson, TJ; Buithieu, J; Chan, S; Charbonneau, F; Genest, J; Hutchison, S; Huyhn, T; Jobin, J; Lonn, E; Poirier, P; Title, L; Tran, T; Walling, A, 2008)
"Amlodipine also was associated with significant slowing of carotid atherosclerosis, an important surrogate marker for CAD, independent of blood pressure modification."2.41Mechanisms of plaque stabilization for a charged calcium channel blocker in coronary artery disease. ( Mason, RP, 2001)
"Hypertension and dyslipidemia are highly co-prevalent, but often poorly controlled, coronary heart disease (CHD) risk factors."1.36Predicted coronary heart disease risk reduction and dual blood pressure/cholesterol goal attainment in patients with hypertension treated in real-world clinical practice. ( Chen, L; Eaddy, M; Jackson, JH; Kean, AJ; Lunacsek, OE; Neutel, JM; Roberts, C, 2010)

Research

Studies (59)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (6.78)18.2507
2000's30 (50.85)29.6817
2010's23 (38.98)24.3611
2020's2 (3.39)2.80

Authors

AuthorsStudies
Sarkar, G1
Gaikwad, VB1
Sharma, A1
Halder, SK1
Kumar, DA1
Anand, J1
Agrawal, S1
Kumbhar, A1
Kinholkar, B1
Mathur, R1
Doshi, M1
Bachani, D1
Mehta, S1
Grigorieva, NY1
Ilyushina, TP1
Yashina, EM1
Foley, M1
Rajkumar, CA1
Shun-Shin, M1
Ganesananthan, S1
Seligman, H1
Howard, J1
Nowbar, AN1
Keeble, TR1
Davies, JR1
Tang, KH1
Gerber, R1
O'Kane, P1
Sharp, ASP1
Petraco, R1
Malik, IS1
Nijjer, S1
Sen, S1
Francis, DP1
Al-Lamee, R1
Liakos, CI1
Papadopoulos, DP1
Kotsis, VT1
Dézsi, CA2
Sakata, K2
Gamou, T2
Tada, H2
Hayashi, K2
Ino, H2
Yamagishi, M2
Bakris, G1
Briasoulis, A1
Dahlof, B1
Jamerson, K1
Weber, MA2
Kelly, RY1
Hester, A1
Hua, T1
Zappe, D2
Pitt, B5
Irons, BK1
Trujillo, A1
Seifert, CF1
Simoni, JS1
Doctolero, S1
Abo-Salem, E1
Meyerrose, GE1
Koyanagi, R2
Hagiwara, N2
Yamaguchi, J2
Kawada-Watanabe, E1
Haruta, S1
Takagi, A2
Ogawa, H2
Kawashiri, MA1
Kanaya, H1
Miwa, K1
Ueda, K1
Higashikata, T1
Mizuno, S1
Michishita, I1
Namura, M1
Nitta, Y1
Katsuda, S1
Okeie, K1
Hirase, H1
Uchiyama, K1
Konno, T1
Nagase, K1
Terashima, M1
Pelliccia, F1
Greco, C1
Gaudio, C1
Rosano, G1
Vitale, C1
Marazzi, G1
Rollini, F1
Angiolillo, DJ1
Kjeldsen, SE1
Berge, E1
Bangalore, S1
Messerli, FH1
Mancia, G1
Holzhauer, B1
Hua, TA1
Zanchetti, A1
Julius, S1
Panov, AV1
Alugishvili, MZ1
Abesadze, IT1
Lohovinina, NL1
Korzenewskaya, KV1
Titenkov, IV1
Kuleshova, EV1
Dyplyakov, DV1
Hohlunov, SM1
Kryukov, AV1
Libis, RA1
Isayeva, EN1
Basyrova, IR1
Safonova, DV1
Forster, T1
Kim, JS1
Park, S2
Yan, P2
Jeffers, BW2
Cerezo, C2
Veeraputhiran, M1
Sundermeyer, M1
Ferrari, R1
de Portu, S3
Mantovani, LG3
Miyauchi, K3
Kojima, T2
Yokoyama, T2
Kurata, T2
Yokoyama, K2
Kawamura, M2
Suwa, S2
Okazaki, S2
Inoue, K2
Fujiwara, Y2
Sumiyoshi, M2
Tanimoto, K2
Nakazato, Y2
Yamagami, S2
Daida, H3
Neutel, JM1
Eaddy, M1
Lunacsek, OE1
Roberts, C1
Chen, L1
Kean, AJ1
Jackson, JH1
Kasanuki, H1
Mori, F1
Nagashima, M1
Yagi, M1
Tamura, H1
Hiro, T1
Komiyama, N1
Ma, J1
Morita, T1
Kaneda, H1
Ueshima, K1
Oba, K1
Yasuno, S1
Fujimoto, A1
Tanaka, S1
Ogihara, T1
Saruta, T1
Nakao, K1
Li, M1
Xu, A1
Lam, KS1
Cheung, BM1
Tse, HF1
Mourad, JJ1
Zamani, P1
Ganz, P1
Libby, P2
Sutradhar, SC1
Rifai, N1
Nicholls, SJ1
Nissen, SE3
Kinlay, S1
Casciano, R2
Doyle, JJ2
Chen, J1
Arikian, S2
Casciano, J2
Kugel, H2
Arocho, R2
Mancini, GB5
Deanfield, JE1
Tuzcu, EM2
Thompson, PD1
Ghali, M1
Garza, D1
Berman, L1
Shi, H1
Buebendorf, E1
Topol, EJ1
Dorval, JF1
Anderson, T1
Buithieu, J2
Chan, S2
Hutchison, S2
Huynh, T1
Jobin, J2
Lonn, E2
Poirier, P2
Title, L2
Walling, A2
Tran, T2
Boudreau, G1
Charbonneau, F2
Genest, J2
Chikamori, T1
Tomiyama, H1
Yamashina, A1
Aboyans, V1
Lacroix, P1
Cassat, C1
Stone, PH1
Rossetti, F1
Menditto, E2
Scalone, L2
Bustacchini, S2
Cricelli, C2
Sorop, O1
Bakker, EN1
Pistea, A1
Spaan, JA1
VanBavel, E1
Brener, SJ1
Ivanc, TB1
Poliszczuk, R1
Chen, M1
Hu, T1
Frid, DJ1
Wang, JG1
Li, Y1
Franklin, SS1
Safar, M1
Anderson, TJ1
Huyhn, T1
Byington, RP2
Miller, ME3
Herrington, D1
Riley, W2
Furberg, CD3
Hunninghake, DB2
Kramsch, DM1
Atkinson, JB1
Henderson, J1
Fox, KM1
Thaulow, E1
Jorgensen, B1
Jeong, MH1
Park, JC2
Rhew, JY1
Kang, KT1
Lee, SH1
Cho, JH1
Kim, NH1
Kim, KH1
Ahn, YK1
Bae, Y1
Cho, JG1
Kim, SH1
Kang, JC1
Vita, JA1
Yeung, AC1
Winniford, M1
Goldstein, MR1
Mason, RP1
Pieper, JA1
Williams, C1
McGuire, A1
Svangren, P1
Kim, R1
Evans, GW1
Byington, R1
Cathomas, G1
Erne, P1
Schwenkglenks, M1
Szucs, TD1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Defining a Gold Standard for Ischaemia: Effects of Interventional Revascularisation Versus Optimum Medical Therapy on Exercise Capacity in Patients With Stable Coronary Artery Disease[NCT02062593]230 participants (Actual)Interventional2013-12-31Completed
Azelnidipine and Amlodipine Anti-Coronary Atherosclerotic Trial in Hypertensive Patients Undergoing Coronary Intervention by Serial Volumetric Intravascular Ultrasound Analysis in Junten Medical University (ALPS-J)[NCT00294567]Phase 4199 participants (Actual)Interventional2005-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Exercise Time on Treadmill

(NCT02062593)
Timeframe: 6 weeks

Interventionseconds (Mean)
Coronary Angioplasty and Optimum Medical Therapy28.4
Sham Procedure and Optimum Medical Therapy11.8

Reviews

10 reviews available for amlodipine and Arteriosclerosis, Coronary

ArticleYear
Optimizing the treatment of hypertension and stable coronary artery disease: clinical evidence for fixed-combination perindopril/amlodipine.
    Current medical research and opinion, 2008, Volume: 24, Issue:12

    Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Clinical Trials as T

2008
Amlodipine: a pharmacoeconomic review.
    Journal of medical economics, 2009, Volume: 12, Issue:1

    Topics: Amlodipine; Antihypertensive Agents; Coronary Artery Disease; Economics, Pharmaceutical; Humans

2009
Which patients benefit the most from the perindopril/amlodipine combination.
    Journal of hypertension, 2011, Volume: 29 Suppl 1

    Topics: Amlodipine; Antihypertensive Agents; Clinical Trials as Topic; Coronary Artery Disease; Humans; Hype

2011
ST-segment analysis in ambulatory ECG (AECG or Holter) monitoring in patients with coronary artery disease: clinical significance and analytic techniques.
    Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2005, Volume: 10, Issue:2

    Topics: Adrenergic beta-Antagonists; Amlodipine; Cardiovascular Agents; Coronary Artery Disease; Diltiazem;

2005
Prevention of stroke and myocardial infarction by amlodipine and Angiotensin receptor blockers: a quantitative overview.
    Hypertension (Dallas, Tex. : 1979), 2007, Volume: 50, Issue:1

    Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Coronary Artery

2007
Limits of lipid-lowering therapy: the potential benefits of amlodipine as an antiatherosclerotic agent.
    International journal of cardiology, 1997, Dec-31, Volume: 62 Suppl 2

    Topics: Amlodipine; Animals; Calcium Channel Blockers; Cholesterol, LDL; Coronary Artery Disease; Drug Thera

1997
Accelerated arteriosclerosis after transplantation: the possible role of calcium channel blockers.
    International journal of cardiology, 1997, Dec-31, Volume: 62 Suppl 2

    Topics: Amlodipine; Animals; Calcium Channel Blockers; Coronary Artery Disease; Coronary Vessels; Diltiazem;

1997
Overview of the prospective randomized evaluation of the vascular effects of Norvasc (amlodipine) trial: PREVENT.
    The Canadian journal of cardiology, 2000, Volume: 16 Suppl D

    Topics: Amlodipine; Calcium Channel Blockers; Carotid Artery Diseases; Coronary Angiography; Coronary Artery

2000
Mechanisms of plaque stabilization for a charged calcium channel blocker in coronary artery disease.
    Pharmacotherapy, 2001, Volume: 21, Issue:9 Pt 2

    Topics: Amlodipine; Calcium Channel Blockers; Coronary Artery Disease; Coronary Disease; Endothelium, Vascul

2001
Management of coronary heart disease risk factors and progression with calcium channel blockers.
    Pharmacotherapy, 2001, Volume: 21, Issue:9 Pt 2

    Topics: Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Ar

2001

Trials

24 trials available for amlodipine and Arteriosclerosis, Coronary

ArticleYear
Fixed-dose Combination of Metoprolol, Telmisartan, and Chlorthalidone for Essential Hypertension in Adults with Stable Coronary Artery Disease: Phase III Study.
    Advances in therapy, 2022, Volume: 39, Issue:2

    Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Coronary Artery Disease;

2022
Achieving Optimal Medical Therapy: Insights From the ORBITA Trial.
    Journal of the American Heart Association, 2021, 02-02, Volume: 10, Issue:3

    Topics: Amlodipine; Bisoprolol; Cardiovascular Agents; Coronary Angiography; Coronary Artery Disease; Dose-R

2021
Low Baseline High-Sensitive C-Reactive Protein is Associated with Coronary Atherosclerosis Regression: Insights from the MILLION Study.
    Journal of atherosclerosis and thrombosis, 2019, May-01, Volume: 26, Issue:5

    Topics: Aged; Amlodipine; Antihypertensive Agents; Atorvastatin; Biomarkers; C-Reactive Protein; Coronary Ar

2019
Comparison of benazepril plus amlodipine or hydrochlorothiazide in high-risk patients with hypertension and coronary artery disease.
    The American journal of cardiology, 2013, Jul-15, Volume: 112, Issue:2

    Topics: Aged; Amlodipine; Antihypertensive Agents; Benzazepines; Coronary Artery Disease; Double-Blind Metho

2013
Effects of direct renin inhibition on atherosclerotic biomarkers in patients with stable coronary artery disease and type 2 diabetes mellitus.
    Journal of cardiovascular pharmacology and therapeutics, 2013, Volume: 18, Issue:5

    Topics: Aged; Amides; Amlodipine; Atherosclerosis; Biomarkers; Blood Pressure; Coronary Artery Disease; Diab

2013
Efficacy of the combination of amlodipine and candesartan in hypertensive patients with coronary artery disease: a subanalysis of the HIJ-CREATE study.
    Journal of cardiology, 2013, Volume: 62, Issue:4

    Topics: Aged; Amlodipine; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Calcium Chan

2013
Impact of combined lipid lowering with blood pressure control on coronary plaque regression: rationale and design of MILLION study.
    Heart and vessels, 2015, Volume: 30, Issue:5

    Topics: Amlodipine; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Coronary Angiography; Coronary Ar

2015
Comparison of the pharmacodynamic effects of ranolazine versus amlodipine on platelet reactivity in stable patients with coronary artery disease treated with dual antiplatelet therapy : The ROMAN (RanOlazine vs. aMlodipine on platelet reactivity in stable
    Journal of thrombosis and thrombolysis, 2015, Volume: 40, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amlodipine; Blood Platelets; Coronary Artery Disease; Dr

2015
No evidence for a J-shaped curve in treated hypertensive patients with increased cardiovascular risk: The VALUE trial.
    Blood pressure, 2016, Volume: 25, Issue:2

    Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Coronary Ar

2016
[The Antihypertensive Effect of the Fixed Combination of Lisinopril and Amlodipine in Patients With Coronary Heart Disease After Coronary Artery Bypass Grafting].
    Kardiologiia, 2015, Volume: 55, Issue:6

    Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Coronary Artery Bypass; Coronary A

2015
Short-Term Cardioprotective Effects of the Original Perindopril/Amlodipine Fixed-Dose Combination in Patients with Stable Coronary Artery Disease: Results of the PAPA-CAD Study.
    Advances in therapy, 2016, Volume: 33, Issue:10

    Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Ca

2016
Effect of inter-individual blood pressure variability on the progression of atherosclerosis in carotid and coronary arteries: a post hoc analysis of the NORMALISE and PREVENT studies.
    European heart journal. Cardiovascular pharmacotherapy, 2017, 04-01, Volume: 3, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Atherosclerosi

2017
Azelnidipine and amlodipine anti-coronary atherosclerosis trial in hypertensive patients undergoing coronary intervention by serial volumetric intravascular ultrasound analysis in Juntendo university (ALPS-J).
    Cardiovascular drugs and therapy, 2009, Volume: 23, Issue:5

    Topics: Adult; Aged; Amlodipine; Azetidinecarboxylic Acid; Calcium Channel Blockers; Coronary Artery Disease

2009
Effect of amlodipine + candesartan on cardiovascular events in hypertensive patients with coronary artery disease (from The Heart Institute of Japan Candesartan Randomized Trial for Evaluation in Coronary Artery Disease [HIJ-CREATE] Study).
    The American journal of cardiology, 2010, Sep-15, Volume: 106, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Angina, Unstable; Angiotensin II Type 1 Receptor Blocker

2010
Azelnidipine and amlodipine anti-coronary atherosclerosis trial in hypertensive patients undergoing coronary intervention by serial volumetric intravascular ultrasound analysis in Juntendo University (ALPS-J).
    Circulation journal : official journal of the Japanese Circulation Society, 2011, Volume: 75, Issue:5

    Topics: Amlodipine; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Coronary Artery Dise

2011
Impact of combination therapy with amlodipine and atorvastatin on plasma adiponectin levels in hypertensive patients with coronary artery disease: combination therapy and adiponectin.
    Postgraduate medicine, 2011, Volume: 123, Issue:6

    Topics: Adiponectin; Aged; Aged, 80 and over; Amlodipine; Anticholesteremic Agents; Antihypertensive Agents;

2011
Relationship of antihypertensive treatment to plasma markers of vascular inflammation and remodeling in the Comparison of Amlodipine versus Enalapril to Limit Occurrences of Thrombosis study.
    American heart journal, 2012, Volume: 163, Issue:4

    Topics: Amlodipine; Antihypertensive Agents; Biomarkers; C-Reactive Protein; Coronary Artery Disease; Corona

2012
[Azelnidipine and amlodipine anti-coronary atherosclerosis trial in hypertensive patients undergoing coronary intervention by serial volumetric intravascular ultrasound analysis in Juntendo Medical University].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2012, Oct-10, Volume: 101, Issue:10

    Topics: Aged; Amlodipine; Azetidinecarboxylic Acid; Blood Pressure; Calcium Channel Blockers; Coronary Arter

2012
Economic benefits of amlodipine treatment in patients with coronary artery disease.
    PharmacoEconomics, 2002, Volume: 20, Issue:8

    Topics: Amlodipine; Calcium Channel Blockers; Coronary Artery Disease; Cost Savings; Female; Humans; Male; M

2002
Effect of antihypertensive agents on cardiovascular events in patients with coronary disease and normal blood pressure: the CAMELOT study: a randomized controlled trial.
    JAMA, 2004, Nov-10, Volume: 292, Issue:18

    Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensi

2004
Reaching recommended lipid and blood pressure targets with amlodipine/atorvastatin combination in patients with coronary heart disease.
    The American journal of cardiology, 2005, Jan-15, Volume: 95, Issue:2

    Topics: Amlodipine; Antihypertensive Agents; Atorvastatin; Blood Pressure; Canada; Cholesterol; Cholesterol,

2005
Modulation of arterial reactivity using amlodipine and atorvastatin measured by ultrasound examination (MARGAUX).
    Atherosclerosis, 2008, Volume: 197, Issue:1

    Topics: Adult; Aged; Amlodipine; Apolipoproteins B; Atorvastatin; Biomarkers; Blood Pressure; Brachial Arter

2008
Results and clinical implications of the CAPARES trial.
    The Canadian journal of cardiology, 2000, Volume: 16 Suppl D

    Topics: Amlodipine; Angina Pectoris; Angioplasty, Balloon, Coronary; Calcium Channel Blockers; Coronary Angi

2000
Effect of amlodipine on the progression of atherosclerosis and the occurrence of clinical events. PREVENT Investigators.
    Circulation, 2000, Sep-26, Volume: 102, Issue:13

    Topics: Aged; Amlodipine; Calcium Channel Blockers; Coronary Artery Disease; Double-Blind Method; Female; Hu

2000

Other Studies

25 other studies available for amlodipine and Arteriosclerosis, Coronary

ArticleYear
[Possibilities of cardioselective beta - blocker bisoprolol therapy in patients having coronary artery disease and bronchial asthma].
    Terapevticheskii arkhiv, 2019, Sep-15, Volume: 91, Issue:9

    Topics: Adrenergic beta-Antagonists; Amlodipine; Asthma; Bisoprolol; Coronary Artery Disease; Humans

2019
Adherence to Treatment, Safety, Tolerance, and Effectiveness of Perindopril/Amlodipine Fixed-Dose Combination in Greek Patients with Hypertension and Stable Coronary Artery Disease: A Pan-Hellenic Prospective Observational Study of Daily Clinical Practice
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2017, Volume: 17, Issue:5

    Topics: Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure;

2017
Treatment with triple combination of atorvastatin, perindopril, and amlodipine in patients with stable coronary artery disease: A subgroup analysis from the PAPA-CAD study.
    The Journal of international medical research, 2018, Volume: 46, Issue:5

    Topics: Amlodipine; Atorvastatin; Blood Pressure; Coronary Artery Disease; Drug Combinations; Electrocardiog

2018
Effect of visit-to-visit blood pressure variability on cardiovascular events in patients with coronary artery disease and well-controlled blood pressure.
    Journal of the American Society of Hypertension : JASH, 2016, Volume: 10, Issue:10

    Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Cardiovascu

2016
Rhabdomyolysis resulting from pharmacologic interaction between erlotinib and simvastatin.
    Clinical lung cancer, 2008, Volume: 9, Issue:4

    Topics: Aged; Amlodipine; Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agents; Antihypertensiv

2008
Predicted coronary heart disease risk reduction and dual blood pressure/cholesterol goal attainment in patients with hypertension treated in real-world clinical practice.
    Journal of clinical hypertension (Greenwich, Conn.), 2010, Volume: 12, Issue:6

    Topics: Amlodipine; Anticholesteremic Agents; Antihypertensive Agents; Atorvastatin; Blood Pressure; Calcium

2010
Intravascular ultrasound parameters in non-inferiority trial.
    Circulation journal : official journal of the Japanese Circulation Society, 2011, Volume: 75, Issue:9

    Topics: Amlodipine; Azetidinecarboxylic Acid; Coronary Artery Disease; Dihydropyridines; Humans; Hypertensio

2011
Influence of coronary risk factors on coronary events in Japanese high-risk hypertensive patients. - Primary and secondary prevention of ischemic heart disease in a subanalysis of the Candesartan Antihypertensive Survival Evaluation in Japan (CASE-J) tria
    Circulation journal : official journal of the Japanese Circulation Society, 2011, Volume: 75, Issue:10

    Topics: Aged; Amlodipine; Antihypertensive Agents; Asian People; Benzimidazoles; Biphenyl Compounds; Coronar

2011
Coronary angiographic changes in patients with cardiac events in the Prospective Randomized Evaluation of the Vascular Effects of Norvasc Trial (PREVENT).
    The American journal of cardiology, 2002, Oct-01, Volume: 90, Issue:7

    Topics: Amlodipine; Calcium Channel Blockers; Coronary Angiography; Coronary Artery Disease; Disease Progres

2002
Targeting the atherosclerotic process in clinical practice. A new look at established agents.
    Atherosclerosis, 2002, Volume: 165, Issue:2

    Topics: Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Calcium Chan

2002
Antihypertensive agents and cardiovascular events in patients with coronary disease and normal blood pressure.
    JAMA, 2005, Mar-09, Volume: 293, Issue:10

    Topics: Amlodipine; Angina Pectoris; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calc

2005
Antihypertensive agents and cardiovascular events in patients with coronary disease and normal blood pressure.
    JAMA, 2005, Mar-09, Volume: 293, Issue:10

    Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Block

2005
Pharmacoeconomic consequences of amlodipine besylate therapy in patients undergoing PTCA.
    Pharmacological research, 2006, Volume: 53, Issue:3

    Topics: Amlodipine; Angioplasty, Balloon, Coronary; Coronary Artery Disease; Coronary Restenosis; Cost-Benef

2006
Calcium channel blockade prevents pressure-dependent inward remodeling in isolated subendocardial resistance vessels.
    American journal of physiology. Heart and circulatory physiology, 2006, Volume: 291, Issue:3

    Topics: Amlodipine; Animals; Blood Pressure; Calcium Channel Blockers; Coronary Artery Disease; Coronary Ste

2006
The pharmacoeconomic impact of amlodipine use on coronary artery disease.
    Pharmacological research, 2006, Volume: 54, Issue:2

    Topics: Adult; Aged; Amlodipine; Calcium Channel Blockers; Coronary Artery Disease; Cost-Benefit Analysis; C

2006
Antihypertensive therapy and regression of coronary artery disease: insights from the Comparison of Amlodipine versus Enalapril to Limit Occurrences of Thrombosis (CAMELOT) and Norvasc for Regression of Manifest Atherosclerotic Lesions by Intravascular So
    American heart journal, 2006, Volume: 152, Issue:6

    Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Block

2006
Rationale, design, and baseline characteristics of the Prospective Randomized Evaluation of the Vascular Effects of Norvasc Trial (PREVENT).
    The American journal of cardiology, 1997, Oct-15, Volume: 80, Issue:8

    Topics: Aged; Amlodipine; Coronary Angiography; Coronary Artery Disease; Coronary Disease; Double-Blind Meth

1997
Can calcium antagonists reverse atherosclerosis?
    European heart journal, 1999, Volume: 20, Issue:13

    Topics: Amlodipine; Calcium Channel Blockers; Coronary Artery Disease; Disease Progression; Humans

1999
Successful management of intractable coronary spasm with a coronary stent.
    Japanese circulation journal, 2000, Volume: 64, Issue:11

    Topics: Adult; Amlodipine; Aspirin; Calcium Channel Blockers; Cardiovascular Agents; Coronary Angiography; C

2000
Coronary artery reactivity after treatment with simvastatin.
    Current atherosclerosis reports, 2001, Volume: 3, Issue:2

    Topics: Amlodipine; Bezafibrate; Coronary Angiography; Coronary Artery Disease; Coronary Disease; Coronary V

2001
Does amlodipine increase cancer incidence?
    Circulation, 2001, Jul-10, Volume: 104, Issue:2

    Topics: Amlodipine; Calcium Channel Blockers; Coronary Artery Disease; Disease Progression; Humans; Incidenc

2001
Amlodipine PREVENTS angina, not atherosclerosis.
    Pharmacotherapy, 2002, Volume: 22, Issue:3

    Topics: Amlodipine; Angina Pectoris; Calcium Channel Blockers; Coronary Artery Disease; Coronary Disease; Di

2002
A cost-effectiveness evaluation of amlodipine usage in patients with coronary artery disease in Sweden.
    International journal of clinical practice, 2002, Volume: 56, Issue:2

    Topics: Amlodipine; Analysis of Variance; Calcium Channel Blockers; Cohort Studies; Coronary Artery Disease;

2002
Post hoc analysis of coronary findings from the prospective randomized evaluation of the vascular effects of the Norvasc trial (PREVENT).
    The American journal of cardiology, 2002, Jun-15, Volume: 89, Issue:12

    Topics: Amlodipine; Calcium Channel Blockers; Coronary Angiography; Coronary Artery Disease; Coronary Diseas

2002
The economic efficiency of amlodipine in the treatment of coronary atherosclerosis--an analysis based on the PREVENT study.
    Cardiovascular drugs and therapy, 2002, Volume: 16, Issue:1

    Topics: Amlodipine; Calcium Channel Blockers; Coronary Artery Disease; Cost-Benefit Analysis; Economics, Pha

2002