Page last updated: 2024-10-22

amlodipine and Arterial Diseases, Carotid

amlodipine has been researched along with Arterial Diseases, Carotid in 9 studies

Amlodipine: A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.
amlodipine : A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.

Research Excerpts

ExcerptRelevanceReference
" However, there are few studies on the regulation and efficacy of atorvastatin combined with amlodipine on Th17/Treg balance in hypertension combined with carotid atherosclerosis."9.69Effects of amlodipine combined with atorvastatin on Th17/Treg imbalance and vascular microcirculation in hypertensive patients with atherosclerosis: A double-blind, single-center randomized controlled trial. ( Qiu, Y; Yang, G, 2023)
" However, there are few studies on the regulation and efficacy of atorvastatin combined with amlodipine on Th17/Treg balance in hypertension combined with carotid atherosclerosis."5.69Effects of amlodipine combined with atorvastatin on Th17/Treg imbalance and vascular microcirculation in hypertensive patients with atherosclerosis: A double-blind, single-center randomized controlled trial. ( Qiu, Y; Yang, G, 2023)
"Since previous studies have reported a beneficial effect of amlodipine and atorvastatin treatment in experimental atherosclerosis, we aimed to investigate the effect of the combination of both drugs on blood and plaque inflammation in patients with carotid stenosis."5.13Treatment with amlodipine and atorvastatin has additive effect on blood and plaque inflammation in hypertensive patients with carotid atherosclerosis. ( Blanco-Colio, LM; Egido, J; Madrigal-Matute, J; Martín-Conejero, A; Martín-Ventura, JL; Muñoz-Garcia, B; Ortega, L; Serrano, J; Vega, M, 2008)
" After a 4-week wash-out period, 209 patients were randomized to either CC 8 mg or AML 5 mg once daily for a minimum of 1 month, after which, if BP was not normalized, the dosage was doubled, followed by the addition of hydrochlorothiazide 12."2.74Effects of candesartan cilexetil on carotid remodeling in hypertensive diabetic patients: the MITEC study. ( Asmar, R; Baguet, JP; Mallion, JM; Nisse-Durgeat, S; Valensi, P, 2009)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (44.44)29.6817
2010's4 (44.44)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Yang, G1
Qiu, Y1
Oh, M1
Lee, CW1
Ahn, JM1
Park, DW1
Kang, SJ1
Lee, SW1
Kim, YH1
Moon, DH1
Park, SW1
Park, SJ1
Kolos, I1
Troitskiy, A1
Balakhonova, T1
Shariya, M1
Skrypnik, D1
Tvorogova, T1
Deev, A1
Boytsov, S1
Kim, JS1
Park, S1
Yan, P1
Jeffers, BW1
Cerezo, C1
Martín-Ventura, JL1
Muñoz-Garcia, B1
Blanco-Colio, LM1
Martín-Conejero, A1
Madrigal-Matute, J1
Vega, M1
Ortega, L1
Serrano, J1
Egido, J1
Zhai, LH1
Wang, SY1
Liang, X1
Yang, CY1
Zhang, RZ1
Wang, ZY1
Tang, J1
Hu, YH1
Baguet, JP1
Asmar, R1
Valensi, P1
Nisse-Durgeat, S1
Mallion, JM1
Kawai, H1
Kurata, T1
Deguchi, K1
Deguchi, S1
Yamashita, T1
Ohta, Y1
Omote, Y1
Kono, S1
Abe, K1
Mancini, GB1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
"Preoperative Identification of the Histologically Vulnerable Plaque Using Non-invasive Imaging, Biomechanical Assessment and Baroreflex Evaluation in Patients With Severe Carotid Stenosis"[NCT05566080]100 participants (Actual)Observational2021-03-15Completed
Carotid Endarterectomy Versus Optimal Medical Treatment of Asymptomatic High Grade Carotid Artery Stenosis[NCT00805311]Phase 4400 participants (Actual)Interventional2009-04-30Terminated (stopped due to Due to the clear advantage of carotid endarterectomy)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for amlodipine and Arterial Diseases, Carotid

ArticleYear
Overview of the prospective randomized evaluation of the vascular effects of Norvasc (amlodipine) trial: PREVENT.
    The Canadian journal of cardiology, 2000, Volume: 16 Suppl D

    Topics: Amlodipine; Calcium Channel Blockers; Carotid Artery Diseases; Coronary Angiography; Coronary Artery

2000

Trials

6 trials available for amlodipine and Arterial Diseases, Carotid

ArticleYear
Effects of amlodipine combined with atorvastatin on Th17/Treg imbalance and vascular microcirculation in hypertensive patients with atherosclerosis: A double-blind, single-center randomized controlled trial.
    Medicine, 2023, Feb-10, Volume: 102, Issue:6

    Topics: Amlodipine; Atherosclerosis; Atorvastatin; Carotid Artery Diseases; Humans; Hypertension; Microcircu

2023
Comparison of fimasartan and amlodipine therapy on carotid atherosclerotic plaque inflammation.
    Clinical cardiology, 2019, Volume: 42, Issue:2

    Topics: Amlodipine; Biphenyl Compounds; Calcium Channel Blockers; Carotid Arteries; Carotid Artery Diseases;

2019
Modern medical treatment with or without carotid endarterectomy for severe asymptomatic carotid atherosclerosis.
    Journal of vascular surgery, 2015, Volume: 62, Issue:4

    Topics: Aged; Amlodipine; Arteriosclerosis; Atorvastatin; Carotid Artery Diseases; Endarterectomy, Carotid;

2015
Modern medical treatment with or without carotid endarterectomy for severe asymptomatic carotid atherosclerosis.
    Journal of vascular surgery, 2015, Volume: 62, Issue:4

    Topics: Aged; Amlodipine; Arteriosclerosis; Atorvastatin; Carotid Artery Diseases; Endarterectomy, Carotid;

2015
Modern medical treatment with or without carotid endarterectomy for severe asymptomatic carotid atherosclerosis.
    Journal of vascular surgery, 2015, Volume: 62, Issue:4

    Topics: Aged; Amlodipine; Arteriosclerosis; Atorvastatin; Carotid Artery Diseases; Endarterectomy, Carotid;

2015
Modern medical treatment with or without carotid endarterectomy for severe asymptomatic carotid atherosclerosis.
    Journal of vascular surgery, 2015, Volume: 62, Issue:4

    Topics: Aged; Amlodipine; Arteriosclerosis; Atorvastatin; Carotid Artery Diseases; Endarterectomy, Carotid;

2015
Effect of inter-individual blood pressure variability on the progression of atherosclerosis in carotid and coronary arteries: a post hoc analysis of the NORMALISE and PREVENT studies.
    European heart journal. Cardiovascular pharmacotherapy, 2017, 04-01, Volume: 3, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Atherosclerosi

2017
Treatment with amlodipine and atorvastatin has additive effect on blood and plaque inflammation in hypertensive patients with carotid atherosclerosis.
    Kidney international. Supplement, 2008, Issue:111

    Topics: Aged; Amlodipine; Anticholesteremic Agents; Atorvastatin; Blood Pressure; Calcium Channel Blockers;

2008
Effects of candesartan cilexetil on carotid remodeling in hypertensive diabetic patients: the MITEC study.
    Vascular health and risk management, 2009, Volume: 5, Issue:1

    Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles;

2009

Other Studies

2 other studies available for amlodipine and Arterial Diseases, Carotid

ArticleYear
[The relationship between the effect of amlodipine on carotid intimal-medial thickness and angiotensin converting enzyme genotypes in elderly hypertensive patients].
    Zhonghua xin xue guan bing za zhi, 2008, Volume: 36, Issue:6

    Topics: Aged; Aged, 80 and over; Amlodipine; Carotid Artery Diseases; Female; Gene Frequency; Genotype; Huma

2008
Combination benefit of amlodipine plus atorvastatin treatment on carotid atherosclerosis in Zucker metabolic rats.
    Neurological research, 2013, Volume: 35, Issue:2

    Topics: Amlodipine; Animals; Antihypertensive Agents; Atorvastatin; Carotid Artery Diseases; Carotid Artery,

2013