amlodipine has been researched along with Alzheimer Disease in 3 studies
Amlodipine: A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.
amlodipine : A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.
Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Excerpt | Relevance | Reference |
|---|---|---|
| "A total of 48 patients with probable AD and essential hypertension were randomly assigned into telmisartan group (n = 24, 40 - 80 mg qd) or amlodipine group (n = 24, 5 - 10 mg qd) for 6 months at Henan Provincial People's Hospital during 2008 - 2011." | 5.16 | [Effects of telmisartan on the level of Aβ1-42, interleukin-1β, tumor necrosis factor α and cognition in hypertensive patients with Alzheimer's disease]. ( Bai, YY; Li, W; Liu, HQ; Lu, F; Ma, MM; Suo, AQ; Wang, JQ; Zhang, JW, 2012) |
| "In patients with hypertension and dementia, nifedipine was associated with increased mortality risk (aHR 1." | 4.02 | Calcium channel blockers, survival and ischaemic stroke in patients with dementia: a Swedish registry study. ( Eriksdotter, M; Garcia-Ptacek, S; Kalar, I; Kramberger, MG; Schwertner, E; Secnik, J; von Euler, M; Winblad, B; Xu, H, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Kalar, I | 1 |
| Xu, H | 1 |
| Secnik, J | 1 |
| Schwertner, E | 1 |
| Kramberger, MG | 1 |
| Winblad, B | 1 |
| von Euler, M | 1 |
| Eriksdotter, M | 1 |
| Garcia-Ptacek, S | 1 |
| Li, W | 1 |
| Zhang, JW | 1 |
| Lu, F | 1 |
| Ma, MM | 1 |
| Wang, JQ | 1 |
| Suo, AQ | 1 |
| Bai, YY | 1 |
| Liu, HQ | 1 |
| Mason, RP | 1 |
1 trial available for amlodipine and Alzheimer Disease
| Article | Year |
|---|---|
[Effects of telmisartan on the level of Aβ1-42, interleukin-1β, tumor necrosis factor α and cognition in hypertensive patients with Alzheimer's disease].
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amlodipine; Amyloid beta-Peptides; Antihypertensive Agen | 2012 |
2 other studies available for amlodipine and Alzheimer Disease
| Article | Year |
|---|---|
Calcium channel blockers, survival and ischaemic stroke in patients with dementia: a Swedish registry study.
Topics: Alzheimer Disease; Amlodipine; Brain Ischemia; Calcium Channel Blockers; Humans; Hypertension; Ische | 2021 |
Probing membrane bilayer interactions of 1,4-dihydropyridine calcium channel blockers. Implications for aging and Alzheimer's disease.
Topics: Aged; Aging; Alzheimer Disease; Amlodipine; Brain Chemistry; Calcium Channel Blockers; Cell Membrane | 1994 |