amlodipine has been researched along with Alloxan Diabetes in 17 studies
Amlodipine: A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.
amlodipine : A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The authors hypothesized that reduction in aldosterone production in diabetes by amlodipine or aliskiren improves diabetic kidney disease by attenuating renal oxidative stress and fibrosis." | 7.79 | Reduction of aldosterone production improves renal oxidative stress and fibrosis in diabetic rats. ( Matavelli, LC; Siragy, HM, 2013) |
| "We hypothesized that compared with hydrochlorothiazide (HCTZ), the renin inhibitor aliskiren (ALISK) or amlodipine (AMLO) and their combination reduce albuminuria via reduction in renal inflammation, independent of blood pressure (BP) changes." | 7.78 | Combined aliskiren and amlodipine reduce albuminuria via reduction in renal inflammation in diabetic rats. ( Huang, J; Matavelli, LC; Siragy, HM, 2012) |
| " Combination therapy of valsartan with either amlodipine or verapamil was equally effective in reducing blood pressure to valsartan monotherapy (valsartan + amlodipine 129 +/- 4 valsartan + verapamil 133 +/- 6 mmHg;) but was not as effective at reducing albuminuria." | 7.72 | Disparate effects of angiotensin II antagonists and calcium channel blockers on albuminuria in experimental diabetes and hypertension: potential role of nephrin. ( Allen, TJ; Cao, Z; Cooper, ME; Davis, BJ; de Gasparo, M; Kawachi, H, 2003) |
| "The results of this study suggested that the L/N-type CCB, cilnidipine, had additive antihypertensive and proteinuria-lowering effects when administered in combination with an ARB, even in type-1 diabetic rats, and that the L-type CCB, amlodipine, did not." | 3.79 | Additive effects of cilnidipine and angiotensin II receptor blocker in preventing the progression of diabetic nephropathy in diabetic spontaneously hypertensive rats. ( Aritomi, S; Konda, T; Niinuma, K; Nitta, K; Ogawa, T, 2013) |
| " The authors hypothesized that reduction in aldosterone production in diabetes by amlodipine or aliskiren improves diabetic kidney disease by attenuating renal oxidative stress and fibrosis." | 3.79 | Reduction of aldosterone production improves renal oxidative stress and fibrosis in diabetic rats. ( Matavelli, LC; Siragy, HM, 2013) |
| "We hypothesized that compared with hydrochlorothiazide (HCTZ), the renin inhibitor aliskiren (ALISK) or amlodipine (AMLO) and their combination reduce albuminuria via reduction in renal inflammation, independent of blood pressure (BP) changes." | 3.78 | Combined aliskiren and amlodipine reduce albuminuria via reduction in renal inflammation in diabetic rats. ( Huang, J; Matavelli, LC; Siragy, HM, 2012) |
| " Combination therapy of valsartan with either amlodipine or verapamil was equally effective in reducing blood pressure to valsartan monotherapy (valsartan + amlodipine 129 +/- 4 valsartan + verapamil 133 +/- 6 mmHg;) but was not as effective at reducing albuminuria." | 3.72 | Disparate effects of angiotensin II antagonists and calcium channel blockers on albuminuria in experimental diabetes and hypertension: potential role of nephrin. ( Allen, TJ; Cao, Z; Cooper, ME; Davis, BJ; de Gasparo, M; Kawachi, H, 2003) |
| "Rosiglitazone-treated rats had restored systolic blood pressure (BP) and normalized plasma insulin level during oral glucose tolerance tests, whereas amlodipine-treated rats restored only systolic BP." | 1.35 | Myocardial heat shock protein 60 expression in insulin-resistant and diabetic rats. ( Chen, HS; Juan, CC; Lin, HD; Wu, TE, 2009) |
| "Amlodipine was given either from day one of diabetes or after 3 or 12 days of established diabetes." | 1.30 | Amlodipine prevents and reverses the elevation in [Ca2+]i and the impaired phagocytosis of PMNL of diabetic rats. ( Demerdash, TM; Marcinkowski, W; Massry, SG; Seyrek, N; Smogorzewski, M, 1997) |
| "Treatment with amlodipine reduced the elevated fasting- and fed-glucose levels significantly." | 1.30 | Effect of chronic treatment with amlodipine in non-insulin-dependent diabetic rats. ( Gokhale, MS; Goyal, RK; Hakim, Z; Santani, DD; Shah, DH, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (23.53) | 18.2507 |
| 2000's | 6 (35.29) | 29.6817 |
| 2010's | 7 (41.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bolanle, IO | 1 |
| Omogbai, EKI | 1 |
| Bafor, EE | 1 |
| Mollnau, H | 1 |
| Oelze, M | 1 |
| Zinßius, E | 1 |
| Hausding, M | 1 |
| Wu, Z | 1 |
| Knorr, M | 1 |
| Ghaemi Kerahrodi, J | 1 |
| Kröller-Schön, S | 1 |
| Jansen, T | 1 |
| Teutsch, C | 1 |
| Foster, C | 1 |
| Li, H | 1 |
| Wenzel, P | 1 |
| Schulz, E | 1 |
| Münzel, T | 1 |
| Daiber, A | 1 |
| Kang, MK | 1 |
| Chung, WB | 1 |
| Hong, SK | 1 |
| Kim, OR | 1 |
| Ihm, SH | 1 |
| Chang, K | 1 |
| Seung, KB | 1 |
| Chen, HS | 1 |
| Wu, TE | 1 |
| Juan, CC | 1 |
| Lin, HD | 1 |
| Khan, MA | 1 |
| Sattar, MA | 1 |
| Abdullah, NA | 1 |
| Abdulla, MH | 1 |
| Salman, IM | 1 |
| Kazi, RN | 1 |
| Swarup, KR | 1 |
| Rathore, HA | 1 |
| Basri, F | 1 |
| Hussain, NM | 1 |
| Dewa, A | 1 |
| Johns, EJ | 1 |
| Sepehr-Ara, L | 1 |
| Sepehr-Ara, M | 1 |
| Mahmoudian, M | 1 |
| Matavelli, LC | 2 |
| Huang, J | 1 |
| Siragy, HM | 2 |
| Aritomi, S | 1 |
| Niinuma, K | 1 |
| Ogawa, T | 1 |
| Konda, T | 1 |
| Nitta, K | 1 |
| Davis, BJ | 1 |
| Cao, Z | 2 |
| de Gasparo, M | 1 |
| Kawachi, H | 1 |
| Cooper, ME | 2 |
| Allen, TJ | 2 |
| Candido, R | 1 |
| Lassila, M | 1 |
| Thallas, V | 1 |
| Jandeleit-Dahm, KA | 1 |
| Lehfeld, LS | 1 |
| Silveira, LA | 1 |
| Ghini, B | 1 |
| Lopes de Faria, JB | 1 |
| de Cavanagh, EM | 1 |
| Ferder, L | 1 |
| Toblli, JE | 1 |
| Piotrkowski, B | 1 |
| Stella, I | 1 |
| Fraga, CG | 1 |
| Inserra, F | 1 |
| Seyrek, N | 1 |
| Marcinkowski, W | 2 |
| Smogorzewski, M | 2 |
| Demerdash, TM | 1 |
| Massry, SG | 2 |
| Zhang, G | 1 |
| Srinivasan, PS | 1 |
| Hakim, ZS | 1 |
| Santani, DD | 2 |
| Goyal, RK | 2 |
| Gokhale, MS | 1 |
| Shah, DH | 1 |
| Hakim, Z | 1 |
17 other studies available for amlodipine and Alloxan Diabetes
| Article | Year |
|---|---|
Effects of amlodipine and valsartan on glibenclamide-treated streptozotocin-induced diabetic rats.
Topics: Amlodipine; Animals; Antihypertensive Agents; Biomarkers; Blood Glucose; Diabetes Mellitus, Experime | 2018 |
Effects of telmisartan or amlodipine monotherapy versus telmisartan/amlodipine combination therapy on vascular dysfunction and oxidative stress in diabetic rats.
Topics: Amlodipine; Animals; Benzimidazoles; Benzoates; Diabetes Mellitus, Experimental; Drug Combinations; | 2013 |
Effects of candesartan cilexetil and amlodipine orotate on receptor for advanced glycation end products expression in the aortic wall of Otsuka Long-Evans Tokushima Fatty (OETFF) type 2 diabetic rats.
Topics: Amlodipine; Animals; Aorta; Benzimidazoles; Biphenyl Compounds; Diabetes Mellitus, Experimental; Dia | 2016 |
Myocardial heat shock protein 60 expression in insulin-resistant and diabetic rats.
Topics: Amlodipine; Animals; Antihypertensive Agents; Chaperonin 60; Diabetes Mellitus, Experimental; Diseas | 2009 |
Functional subtypes of renal alpha1-adrenoceptor in spontaneously hypertensive rats with streptozotocin-induced experimental diabetic nephropathy.
Topics: Adrenergic Antagonists; Amlodipine; Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies | 2009 |
Effect of the two new calcium channel blockers mebudipine and dibudipine in comparison to amlodipine on vascular flow of isolated kidney of diabetic rat.
Topics: Amlodipine; Animals; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Diab | 2010 |
Combined aliskiren and amlodipine reduce albuminuria via reduction in renal inflammation in diabetic rats.
Topics: Albuminuria; Amides; Amlodipine; Animals; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus | 2012 |
Additive effects of cilnidipine and angiotensin II receptor blocker in preventing the progression of diabetic nephropathy in diabetic spontaneously hypertensive rats.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Biomarkers; B | 2013 |
Reduction of aldosterone production improves renal oxidative stress and fibrosis in diabetic rats.
Topics: Aldosterone; Amides; Amlodipine; Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Cy | 2013 |
Disparate effects of angiotensin II antagonists and calcium channel blockers on albuminuria in experimental diabetes and hypertension: potential role of nephrin.
Topics: Albuminuria; Amlodipine; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood P | 2003 |
Irbesartan but not amlodipine suppresses diabetes-associated atherosclerosis.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Aortic Diseas | 2004 |
Early blood pressure normalization independent of the class of antihypertensive agent prevents augmented renal fibronectin and albuminuria in experimental diabetic nephropathy.
Topics: Albuminuria; Amlodipine; Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Body Weigh | 2004 |
Renal mitochondrial impairment is attenuated by AT1 blockade in experimental Type I diabetes.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Antioxidants; | 2008 |
Amlodipine prevents and reverses the elevation in [Ca2+]i and the impaired phagocytosis of PMNL of diabetic rats.
Topics: Amlodipine; Animals; Calcium; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Neutrophils | 1997 |
Elevation of [Ca2+]i of renal proximal tubular cells and down-regulation of mRNA of PTH-PTHrP, V1a and AT1 receptors in kidney of diabetic rats.
Topics: Amlodipine; Angiotensin I; Animals; Autoradiography; Calcium; Calcium Channel Blockers; Diabetes Mel | 1997 |
Effects of chronic treatment with amlodipine in streptozotocin-diabetic and spontaneously hypertensive rats.
Topics: Amlodipine; Animals; Blood Glucose; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Exp | 1997 |
Effect of chronic treatment with amlodipine in non-insulin-dependent diabetic rats.
Topics: Amlodipine; Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Calcium Channel Blocker | 1998 |