amlodipine has been researched along with Adverse Drug Event in 17 studies
Amlodipine: A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.
amlodipine : A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hypertension and hyperhomocysteinemia (HHcy) have long been associated with adverse cardiovascular and cerebrovascular health outcomes." | 9.51 | Effects of individualized administration of folic acid on prothrombotic state and vascular endothelial function with H-type hypertension: A double-blinded, randomized clinical cohort study. ( He, H; Hou, A; Luo, M; Ran, S; Song, D; Tang, J; Tang, Y; Wang, H; Wang, T; Yan, X; Yang, R; Yu, B; Zhang, S, 2022) |
| "Patients with Stage 1 or 2 hypertension were randomized to telmisartan 0, 20, 40, or 80 mg plus amlodipine 0, 2." | 9.14 | Telmisartan plus amlodipine in patients with moderate or severe hypertension: results from a subgroup analysis of a randomized, placebo-controlled, parallel-group, 4 x 4 factorial study. ( Guthrie, R; Kobe, M; Littlejohn, TW; Majul, CR; Oigman, W; Olvera, R; Seeber, M, 2009) |
| " Safety and tolerability were assessed by the incidence rate of adverse events (AEs) and discontinuation." | 5.56 | Real-World Effectiveness and Safety of a Single-Pill Combination of Olmesartan/Amlodipine/Hydrochlorothiazide in Korean Patients with Essential Hypertension (RESOLVE): A Large, Observational, Retrospective, Cohort Study. ( Park, SJ; Rhee, SJ, 2020) |
| "Hypertension and hyperhomocysteinemia (HHcy) have long been associated with adverse cardiovascular and cerebrovascular health outcomes." | 5.51 | Effects of individualized administration of folic acid on prothrombotic state and vascular endothelial function with H-type hypertension: A double-blinded, randomized clinical cohort study. ( He, H; Hou, A; Luo, M; Ran, S; Song, D; Tang, J; Tang, Y; Wang, H; Wang, T; Yan, X; Yang, R; Yu, B; Zhang, S, 2022) |
| "Pedal oedema is a well-known adverse effect of amlodipine, but significantly less frequent if only half of the maximum recommended dosage is used." | 5.41 | ( Christensen, B; Helgestad, OK; Henriksen, JN; Oxlund, CS; Skovbjerg, BK, 2023) |
| "This randomized, double-blind study evaluated efficacy of a single-pill combination of amlodipine/valsartan (Aml/Val) in Asian patients with hypertension not responding to Val 80 mg." | 5.15 | Efficacy and tolerability of a single-pill combination of amlodipine/valsartan in Asian hypertensive patients not adequately controlled with valsartan monotherapy. ( Curt, V; Hao, YM; Huang, J; Sun, NL; Tu, Y; Zhang, Y; Zhu, JR, 2011) |
| "Patients with Stage 1 or 2 hypertension were randomized to telmisartan 0, 20, 40, or 80 mg plus amlodipine 0, 2." | 5.14 | Telmisartan plus amlodipine in patients with moderate or severe hypertension: results from a subgroup analysis of a randomized, placebo-controlled, parallel-group, 4 x 4 factorial study. ( Guthrie, R; Kobe, M; Littlejohn, TW; Majul, CR; Oigman, W; Olvera, R; Seeber, M, 2009) |
| "The aim of this randomized, double-blind, multicenter 12-week study was to compare the efficacy, safety, and tolerability of a combination of olmesartan medoxomil/hydrochlorothiazide (HCTZ) with that of benazepril plus amlodipine besylate in patients with stage 2 hypertension." | 5.12 | Efficacy and safety of olmesartan medoxomil and hydrochlorothiazide compared with benazepril and amlodipine besylate. ( Dubiel, R; Kereiakes, DJ; Lipka, LJ; Neutel, JM; Punzi, HA; Xu, J, 2007) |
| " As a rare and unique adverse effect of infliximab, hypertension should be paid enough attention in clinical work." | 1.72 | Hypertension as a rare adverse effect caused by infliximab in the treatment of Crohn's disease: a case report. ( Mo, J; Tang, J; Zhang, B; Zhao, X, 2022) |
| " Safety and tolerability were assessed by the incidence rate of adverse events (AEs) and discontinuation." | 1.56 | Real-World Effectiveness and Safety of a Single-Pill Combination of Olmesartan/Amlodipine/Hydrochlorothiazide in Korean Patients with Essential Hypertension (RESOLVE): A Large, Observational, Retrospective, Cohort Study. ( Park, SJ; Rhee, SJ, 2020) |
| "5 million adverse drug reaction (ADR) reports for 8620 drugs/biologics that are listed for 1191 Coding Symbols for Thesaurus of Adverse Reaction (COSTAR) terms of adverse effects." | 1.32 | Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. ( Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.88) | 18.2507 |
| 2000's | 3 (17.65) | 29.6817 |
| 2010's | 9 (52.94) | 24.3611 |
| 2020's | 4 (23.53) | 2.80 |
| Authors | Studies |
|---|---|
| Matthews, EJ | 1 |
| Kruhlak, NL | 1 |
| Weaver, JL | 1 |
| Benz, RD | 1 |
| Contrera, JF | 1 |
| Liu, Z | 1 |
| Shi, Q | 1 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Fang, H | 1 |
| Tong, W | 1 |
| Sakatis, MZ | 1 |
| Reese, MJ | 1 |
| Harrell, AW | 1 |
| Taylor, MA | 1 |
| Baines, IA | 1 |
| Chen, L | 1 |
| Bloomer, JC | 1 |
| Yang, EY | 1 |
| Ellens, HM | 1 |
| Ambroso, JL | 1 |
| Lovatt, CA | 1 |
| Ayrton, AD | 1 |
| Clarke, SE | 1 |
| Morgan, RE | 1 |
| van Staden, CJ | 1 |
| Chen, Y | 1 |
| Kalyanaraman, N | 1 |
| Kalanzi, J | 1 |
| Dunn, RT | 1 |
| Afshari, CA | 1 |
| Hamadeh, HK | 1 |
| Zhang, S | 1 |
| Wang, T | 1 |
| Wang, H | 1 |
| Tang, J | 2 |
| Hou, A | 1 |
| Yan, X | 1 |
| Yu, B | 1 |
| Ran, S | 1 |
| Luo, M | 1 |
| Tang, Y | 1 |
| Yang, R | 1 |
| Song, D | 1 |
| He, H | 1 |
| Zhao, X | 1 |
| Mo, J | 1 |
| Zhang, B | 1 |
| Skovbjerg, BK | 1 |
| Helgestad, OK | 1 |
| Oxlund, CS | 1 |
| Christensen, B | 1 |
| Henriksen, JN | 1 |
| Park, SJ | 1 |
| Rhee, SJ | 1 |
| Kobalava, Z | 1 |
| Troitskaya, E | 1 |
| Ezhova, N | 1 |
| Ayyagari, R | 1 |
| Xie, J | 1 |
| Cheng, D | 1 |
| Wu, EQ | 1 |
| Huang, XY | 1 |
| Chen, S | 1 |
| Preiss, AK | 1 |
| Roughead, EE | 1 |
| Pratt, NL | 1 |
| Glezer, MG | 1 |
| Vygodin, VA | 1 |
| Avakian, AA | 1 |
| Prokof'eva, EB | 1 |
| Littlejohn, TW | 1 |
| Majul, CR | 1 |
| Olvera, R | 1 |
| Seeber, M | 1 |
| Kobe, M | 1 |
| Guthrie, R | 1 |
| Oigman, W | 1 |
| Huang, J | 1 |
| Sun, NL | 1 |
| Hao, YM | 1 |
| Zhu, JR | 1 |
| Tu, Y | 1 |
| Curt, V | 1 |
| Zhang, Y | 1 |
| Arimanickam, G | 1 |
| Kereiakes, DJ | 1 |
| Neutel, JM | 1 |
| Punzi, HA | 1 |
| Xu, J | 1 |
| Lipka, LJ | 1 |
| Dubiel, R | 1 |
| Gautam, CS | 1 |
| Malhotra, S | 1 |
| Goel, NK | 1 |
2 reviews available for amlodipine and Adverse Drug Event
| Article | Year |
|---|---|
Topics: Amlodipine; Ankle; Calcium Channel Blockers; Drug-Related Side Effects and Adverse Reactions; Edema; | 2023 |
[Fixed-Drug Combination Amlodipine, Indapamide and Perindopril: New Horizons of Antihypertensive Therapy].
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Combinations; Drug Therapy, Combination; D | 2017 |
4 trials available for amlodipine and Adverse Drug Event
| Article | Year |
|---|---|
Effects of individualized administration of folic acid on prothrombotic state and vascular endothelial function with H-type hypertension: A double-blinded, randomized clinical cohort study.
Topics: Amlodipine; Cohort Studies; Double-Blind Method; Drug-Related Side Effects and Adverse Reactions; Fe | 2022 |
Telmisartan plus amlodipine in patients with moderate or severe hypertension: results from a subgroup analysis of a randomized, placebo-controlled, parallel-group, 4 x 4 factorial study.
Topics: Amlodipine; Analysis of Variance; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates | 2009 |
Efficacy and tolerability of a single-pill combination of amlodipine/valsartan in Asian hypertensive patients not adequately controlled with valsartan monotherapy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Ant | 2011 |
Efficacy and safety of olmesartan medoxomil and hydrochlorothiazide compared with benazepril and amlodipine besylate.
Topics: Amlodipine; Antihypertensive Agents; Benzazepines; Blood Pressure; Diastole; Drug-Related Side Effec | 2007 |
11 other studies available for amlodipine and Adverse Drug Event
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Dru | 2004 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily | 2013 |
Hypertension as a rare adverse effect caused by infliximab in the treatment of Crohn's disease: a case report.
Topics: Adult; Amlodipine; Antihypertensive Agents; Crohn Disease; Drug-Related Side Effects and Adverse Rea | 2022 |
Real-World Effectiveness and Safety of a Single-Pill Combination of Olmesartan/Amlodipine/Hydrochlorothiazide in Korean Patients with Essential Hypertension (RESOLVE): A Large, Observational, Retrospective, Cohort Study.
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Asian People; Cohort Studies; D | 2020 |
A retrospective study evaluating the tolerability and effectiveness of adjunctive antihypertensive drugs in patients with inadequate response to initial treatment.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Drug-Related Side Effects and Adverse Reactions; F | 2018 |
Sequence symmetry analysis graphic adjustment for prescribing trends.
Topics: Adverse Drug Reaction Reporting Systems; Amlodipine; Databases, Factual; Drug Prescriptions; Drug-Re | 2019 |
[Results of the Russian EKSPERT program: post-marketing supervision over efficacy and influence of the preparation Ekvator on quality of life at out-patients with arterial hypertension].
Topics: Aged; Ambulatory Care; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitorin | 2014 |
Tube feeding and drugs in intensive care unit.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Critical Care; Delaye | 2011 |
Consumer product information: how rational the information is?
Topics: Amlodipine; Animals; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Rabbits | 1998 |