amlodipine has been researched along with Acute Liver Injury, Drug-Induced in 12 studies
Amlodipine: A long-acting dihydropyridine calcium channel blocker. It is effective in the treatment of ANGINA PECTORIS and HYPERTENSION.
amlodipine : A fully substituted dialkyl 1,4-dihydropyridine-3,5-dicarboxylate derivative, which is used for the treatment of hypertension, chronic stable angina and confirmed or suspected vasospastic angina.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Amlodipine was started for steroid-induced hypertension; 11 days after its initiation, alanine aminotransferase and aspartate aminotransferase peaked at 630 and 421 IU/L, respectively." | 3.81 | Possible amlodipine-induced hepatotoxicity after stem cell transplant. ( Hammerstrom, AE, 2015) |
| "Arterial hypertension is a highly manageable disorder due to a variety of drugs available for its treatment." | 2.58 | Noncholestatic acute hepatocellular injury following candesartan administration. ( DeObeso-Gonzalez, E; Flores-Villalba, E; Lammel-Lindemann, JA; Martagón, AJ; Puente-Gallegos, F, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 10 (83.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fourches, D | 1 |
| Barnes, JC | 1 |
| Day, NC | 1 |
| Bradley, P | 1 |
| Reed, JZ | 1 |
| Tropsha, A | 1 |
| Liu, Z | 1 |
| Shi, Q | 1 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Fang, H | 1 |
| Tong, W | 2 |
| Sakatis, MZ | 1 |
| Reese, MJ | 1 |
| Harrell, AW | 1 |
| Taylor, MA | 1 |
| Baines, IA | 1 |
| Chen, L | 1 |
| Bloomer, JC | 1 |
| Yang, EY | 1 |
| Ellens, HM | 1 |
| Ambroso, JL | 1 |
| Lovatt, CA | 1 |
| Ayrton, AD | 1 |
| Clarke, SE | 1 |
| Warner, DJ | 1 |
| Chen, H | 1 |
| Cantin, LD | 1 |
| Kenna, JG | 1 |
| Stahl, S | 1 |
| Walker, CL | 1 |
| Noeske, T | 1 |
| Morgan, RE | 1 |
| van Staden, CJ | 1 |
| Chen, Y | 1 |
| Kalyanaraman, N | 1 |
| Kalanzi, J | 1 |
| Dunn, RT | 1 |
| Afshari, CA | 1 |
| Hamadeh, HK | 1 |
| Chen, M | 1 |
| Suzuki, A | 1 |
| Thakkar, S | 1 |
| Yu, K | 1 |
| Hu, C | 1 |
| Lammel-Lindemann, JA | 1 |
| Flores-Villalba, E | 1 |
| Martagón, AJ | 1 |
| DeObeso-Gonzalez, E | 1 |
| Puente-Gallegos, F | 1 |
| Kaya, H | 1 |
| Polat, B | 1 |
| Albayrak, A | 1 |
| Mercantepe, T | 1 |
| Buyuk, B | 1 |
| Demirci, H | 1 |
| Polat, Z | 1 |
| Kantarcioglu, M | 1 |
| Kekilli, M | 1 |
| Uygun, A | 1 |
| Bagci, S | 1 |
| Hammerstrom, AE | 1 |
| de Luis, DA | 1 |
| Aller, R | 1 |
| Moreira, V | 1 |
| López Vivancos, J | 1 |
| Bara Oliván, B | 1 |
| Muñiz García, R | 1 |
2 reviews available for amlodipine and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Pr | 2016 |
Noncholestatic acute hepatocellular injury following candesartan administration.
Topics: Adult; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; | 2018 |
10 other studies available for amlodipine and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI | 2010 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily | 2013 |
Protective effect of an L-type calcium channel blocker, amlodipine, on paracetamol-induced hepatotoxicity in rats.
Topics: Acetaminophen; Amlodipine; Animals; Anti-Inflammatory Agents; Antioxidants; Calcium Channel Blockers | 2018 |
Short-term amlodipine induced liver injury : an extremely rare acute complication.
Topics: Amlodipine; Calcium Channel Blockers; Chemical and Drug Induced Liver Injury; Diagnosis, Differentia | 2013 |
Possible amlodipine-induced hepatotoxicity after stem cell transplant.
Topics: Aged; Alanine Transaminase; Amlodipine; Antihypertensive Agents; Aspartate Aminotransferases; Chemic | 2015 |
[Hepatic toxicity and amlodipine].
Topics: Aged; Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Chemical and Drug Induced Liver | 1998 |
[Toxic hepatitis caused by amlodipine].
Topics: Aged; Amlodipine; Calcium Channel Blockers; Chemical and Drug Induced Liver Injury; Humans; Male | 2002 |