amlexanox has been researched along with Stomatitis, Aphthous in 17 studies
amlexanox: SRA-A antagonist;structure given in first source
amlexanox : A pyridochromene-derived monocarboxylic acid having an amino substituent at the 2-position, an oxo substituent at the 5-position and an isopropyl substituent at the 7-position.
Stomatitis, Aphthous: A recurrent disease of the oral mucosa of unknown etiology. It is characterized by small white ulcerative lesions, single or multiple, round or oval. Two to eight crops of lesions occur per year, lasting for 7 to 14 days and then heal without scarring. (From Jablonski's Dictionary of Dentistry, 1992, p742)
| Excerpt | Relevance | Reference |
|---|---|---|
| "041)] was the most effective in reducing the pain score followed by Amlexanox [MD, -2." | 5.41 | COMPARATIVE EFFICACY OF THERAPEUTIC INTERVENTIONS FOR THE MANAGEMENT OF RECURRENT APHTHOUS ULCERS: A SYSTEMATIC REVIEW AND NETWORK META-ANALYSIS. ( Cheng, YO; Gopinath, D; Shetty, NY; Syeed, MS; Veettil, SK, 2023) |
| "Amlexanox oral adhesive tablets are effective and safe in reducing aphthous ulcer pain and lesion size, as well as erythema and exudation in this Chinese cohort." | 5.12 | An evaluation on the efficacy and safety of amlexanox oral adhesive tablets in the treatment of recurrent minor aphthous ulceration in a Chinese cohort: a randomized, double-blind, vehicle-controlled, unparallel multicenter clinical trial. ( Cai, Y; Chen, F; Chen, Q; Lin, M; Liu, J; Shi, J; Wang, Y; Wang, Z; Zeng, X; Zhang, Y; Zhou, H, 2006) |
| "Both amlexanox and LLLT were equally effective in relieving pain associated with minor aphthous stomatitis." | 2.82 | Low-level laser therapy versus 5% amlexanox: a comparison of treatment effects in a cohort of patients with minor aphthous ulcers. ( Anjana, R; Jaishankar, HP; Jijin, MJ; Kavitha, AP; Krupashankar, R; Pai, J; Rakaraddi, M; Shobha, R, 2016) |
| "Amlexanox has been developed as a 5 percent topical oral paste for the treatment of patients with recurrent aphthous stomatitis (RAS) in most European countries." | 2.74 | A clinical evaluation of amlexanox oral adhesive pellicles in the treatment of recurrent aphthous stomatitis and comparison with amlexanox oral tablets: a randomized, placebo controlled, blinded, multicenter clinical trial. ( Chen, Q; Chen, R; Dong, Y; Gao, F; Jiang, L; Lin, M; Liu, J; Meng, W; Wang, Z; Xu, T; Zeng, X; Zhong, X; Zhou, H, 2009) |
| " Minimal adverse experiences were observed with the 991 subjects that were exposed to 5% Amlexanox paste." | 2.68 | 5% amlexanox oral paste, a new treatment for recurrent minor aphthous ulcers: II. Pharmacokinetics and demonstration of clinical safety. ( Alfano, MC; Charney, MR; Khandwala, A; Van Inwegen, RG, 1997) |
| "Levamisole has shown variable efficacy in reducing ulcer frequency and duration in patients with minor RAU." | 2.41 | Treatment strategies for recurrent oral aphthous ulcers. ( Barrons, RW, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (23.53) | 18.2507 |
| 2000's | 9 (52.94) | 29.6817 |
| 2010's | 3 (17.65) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Cheng, YO | 1 |
| Veettil, SK | 1 |
| Syeed, MS | 1 |
| Shetty, NY | 1 |
| Gopinath, D | 1 |
| Jijin, MJ | 1 |
| Rakaraddi, M | 1 |
| Pai, J | 1 |
| Jaishankar, HP | 1 |
| Krupashankar, R | 1 |
| Kavitha, AP | 1 |
| Anjana, R | 1 |
| Shobha, R | 1 |
| Pentapati, KC | 1 |
| Smriti, K | 1 |
| Gadicherla, S | 1 |
| Höger, P | 1 |
| Meng, W | 1 |
| Dong, Y | 1 |
| Liu, J | 2 |
| Wang, Z | 2 |
| Zhong, X | 1 |
| Chen, R | 1 |
| Zhou, H | 2 |
| Lin, M | 2 |
| Jiang, L | 1 |
| Gao, F | 1 |
| Xu, T | 1 |
| Chen, Q | 2 |
| Zeng, X | 2 |
| Bailey, J | 1 |
| McCarthy, C | 1 |
| Smith, RF | 1 |
| Murray, B | 2 |
| McGuinness, N | 1 |
| Biagioni, P | 1 |
| Hyland, P | 1 |
| Lamey, PJ | 2 |
| Biagioni, PA | 1 |
| Cai, Y | 1 |
| Chen, F | 1 |
| Wang, Y | 1 |
| Shi, J | 1 |
| Zhang, Y | 1 |
| Rodríguez, M | 1 |
| Rubio, JA | 1 |
| Sanchez, R | 1 |
| Burgess, JA | 1 |
| van der Ven, PF | 1 |
| Martin, M | 1 |
| Sherman, J | 1 |
| Haley, J | 1 |
| Greer, RO | 1 |
| Lindenmuth, JE | 1 |
| Juarez, T | 1 |
| Khandwala, A | 4 |
| Van Inwegen, RG | 2 |
| Charney, MR | 1 |
| Alfano, MC | 2 |
| Binnie, WH | 1 |
| Curro, FA | 1 |
| Van Inwegan, RG | 1 |
| Barrons, RW | 1 |
| Eisen, D | 1 |
| Lynch, DP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Nonaromatic Naphthalan - Composition Study and Biological Effects on Epithelial Tissues[NCT02920658] | Phase 2 | 57 participants (Actual) | Interventional | 2010-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for amlexanox and Stomatitis, Aphthous
| Article | Year |
|---|---|
COMPARATIVE EFFICACY OF THERAPEUTIC INTERVENTIONS FOR THE MANAGEMENT OF RECURRENT APHTHOUS ULCERS: A SYSTEMATIC REVIEW AND NETWORK META-ANALYSIS.
Topics: Aminopyridines; Humans; Network Meta-Analysis; Pain; Stomatitis, Aphthous | 2023 |
Clinical inquiry. What is the most effective way to treat recurrent canker sores?
Topics: Administration, Topical; Aminopyridines; Anti-Allergic Agents; Anti-Infective Agents, Local; Anti-In | 2011 |
Review of over-the-counter treatments for aphthous ulceration and results from use of a dissolving oral patch containing glycyrrhiza complex herbal extract.
Topics: Aminopyridines; Anesthetics, Local; Cyanoacrylates; Glycyrrhiza; Hematinics; Humans; Mouthwashes; No | 2008 |
Treatment strategies for recurrent oral aphthous ulcers.
Topics: Adjuvants, Immunologic; Administration, Topical; Adrenal Cortex Hormones; Aminopyridines; Anti-Infla | 2001 |
Selecting topical and systemic agents for recurrent aphthous stomatitis.
Topics: Administration, Topical; Aminopyridines; Anti-Inflammatory Agents; Humans; Prednisone; Recurrence; S | 2001 |
10 trials available for amlexanox and Stomatitis, Aphthous
| Article | Year |
|---|---|
Low-level laser therapy versus 5% amlexanox: a comparison of treatment effects in a cohort of patients with minor aphthous ulcers.
Topics: Adolescent; Adult; Aminopyridines; Anti-Allergic Agents; Female; Humans; India; Low-Level Light Ther | 2016 |
A clinical evaluation of amlexanox oral adhesive pellicles in the treatment of recurrent aphthous stomatitis and comparison with amlexanox oral tablets: a randomized, placebo controlled, blinded, multicenter clinical trial.
Topics: Adhesiveness; Administration, Oral; Aminopyridines; Anti-Allergic Agents; China; Double-Blind Method | 2009 |
A comparative study of the efficacy of Aphtheal in the management of recurrent minor aphthous ulceration.
Topics: Adult; Aminopyridines; Anti-Allergic Agents; Body Temperature; Erythema; Female; Humans; Male; Secon | 2005 |
The efficacy of amlexanox OraDisc on the prevention of recurrent minor aphthous ulceration.
Topics: Administration, Topical; Adult; Aminopyridines; Anti-Allergic Agents; Body Temperature; Double-Blind | 2006 |
An evaluation on the efficacy and safety of amlexanox oral adhesive tablets in the treatment of recurrent minor aphthous ulceration in a Chinese cohort: a randomized, double-blind, vehicle-controlled, unparallel multicenter clinical trial.
Topics: Adhesives; Adolescent; Adult; Aged; Aminopyridines; Anti-Allergic Agents; Cohort Studies; Double-Bli | 2006 |
Effectiveness of two oral pastes for the treatment of recurrent aphthous stomatitis.
Topics: Aminopyridines; Analysis of Variance; Anti-Allergic Agents; Anti-Inflammatory Agents; Clobetasol; Do | 2007 |
A double-blind study of topically applied 5% amlexanox in the treatment of aphthous ulcers.
Topics: Administration, Oral; Administration, Topical; Adolescent; Adult; Aged; Aminopyridines; Anti-Inflamm | 1993 |
5% amlexanox oral paste, a new treatment for recurrent minor aphthous ulcers: II. Pharmacokinetics and demonstration of clinical safety.
Topics: Administration, Topical; Adult; Aminopyridines; Anti-Inflammatory Agents; Area Under Curve; Dose-Res | 1997 |
5% amlexanox oral paste, a new treatment for recurrent minor aphthous ulcers: I. Clinical demonstration of acceleration of healing and resolution of pain.
Topics: Administration, Topical; Adult; Aminopyridines; Analysis of Variance; Anti-Inflammatory Agents; Dose | 1997 |
Amlexanox oral paste: a novel treatment that accelerates the healing of aphthous ulcers.
Topics: Administration, Topical; Adult; Aminopyridines; Anti-Inflammatory Agents; Chi-Square Distribution; D | 1997 |
2 other studies available for amlexanox and Stomatitis, Aphthous
| Article | Year |
|---|---|
Low-level laser therapy versus 5% amlexanox: a comparison of treatment effects in a cohort of minor aphthous ulcers patients-a commentary.
Topics: Aminopyridines; Humans; Low-Level Light Therapy; Pain Measurement; Recurrence; Stomatitis, Aphthous | 2016 |
[Local Treatment of stomatitis aphthosa].
Topics: Administration, Topical; Aminopyridines; Anti-Allergic Agents; Humans; Stomatitis, Aphthous | 2008 |