amlexanox has been researched along with Melanoma in 2 studies
amlexanox: SRA-A antagonist;structure given in first source
amlexanox : A pyridochromene-derived monocarboxylic acid having an amino substituent at the 2-position, an oxo substituent at the 5-position and an isopropyl substituent at the 7-position.
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In vivo, we applied a mouse melanoma skin cancer model to assess tumour growth and melanoma-associated pain in IKKε knockout mice as well as C57BL/6 mice after inoculation with IKKε-negative cells." | 1.43 | The protein kinase IKKepsilon contributes to tumour growth and tumour pain in a melanoma model. ( Geisslinger, G; King-Himmelreich, TS; Laarmann, K; Meissner, M; Möser, CV; Niederberger, E; Olbrich, K; Wolters, MC, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Möller, M | 1 |
| Wasel, J | 1 |
| Schmetzer, J | 1 |
| Weiß, U | 1 |
| Meissner, M | 2 |
| Schiffmann, S | 1 |
| Weigert, A | 1 |
| Möser, CV | 2 |
| Niederberger, E | 2 |
| Laarmann, K | 1 |
| Olbrich, K | 1 |
| King-Himmelreich, TS | 1 |
| Wolters, MC | 1 |
| Geisslinger, G | 1 |
2 other studies available for amlexanox and Melanoma
| Article | Year |
|---|---|
The Specific IKKε/TBK1 Inhibitor Amlexanox Suppresses Human Melanoma by the Inhibition of Autophagy, NF-κB and MAP Kinase Pathways.
Topics: Aminopyridines; Animals; Autophagy; Cell Line, Tumor; Cell Movement; Cell Proliferation; Humans; I-k | 2020 |
The protein kinase IKKepsilon contributes to tumour growth and tumour pain in a melanoma model.
Topics: Aminopyridines; Animals; Cell Cycle; Cell Line; Cell Line, Tumor; Cell Proliferation; Humans; I-kapp | 2016 |