amlexanox has been researched along with Cockayne-Touraine Disease in 1 studies
amlexanox: SRA-A antagonist;structure given in first source
amlexanox : A pyridochromene-derived monocarboxylic acid having an amino substituent at the 2-position, an oxo substituent at the 5-position and an isopropyl substituent at the 7-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Recessive dystrophic epidermolysis bullosa (RDEB) is a rare monogenic blistering disorder caused by the lack of functional type VII collagen, leading to skin fragility and subsequent trauma-induced separation of the epidermis from the underlying dermis." | 2.55 | Amlexanox Enhances Premature Termination Codon Read-Through in COL7A1 and Expression of Full Length Type VII Collagen: Potential Therapy for Recessive Dystrophic Epidermolysis Bullosa. ( Atanasova, VS; Bruckner-Tuderman, L; Chen, M; Gruber, C; Has, C; Jiang, Q; McGrath, JA; Piñón Hofbauer, J; Prisco, M; South, AP; Uitto, J, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Atanasova, VS | 1 |
| Jiang, Q | 1 |
| Prisco, M | 1 |
| Gruber, C | 1 |
| Piñón Hofbauer, J | 1 |
| Chen, M | 1 |
| Has, C | 1 |
| Bruckner-Tuderman, L | 1 |
| McGrath, JA | 1 |
| Uitto, J | 1 |
| South, AP | 1 |
1 review available for amlexanox and Cockayne-Touraine Disease
| Article | Year |
|---|---|
Amlexanox Enhances Premature Termination Codon Read-Through in COL7A1 and Expression of Full Length Type VII Collagen: Potential Therapy for Recessive Dystrophic Epidermolysis Bullosa.
Topics: Aminopyridines; Codon, Nonsense; Collagen Type VII; Epidermolysis Bullosa Dystrophica; Female; Gene | 2017 |