amlexanox has been researched along with Aphthae in 17 studies
amlexanox: SRA-A antagonist;structure given in first source
amlexanox : A pyridochromene-derived monocarboxylic acid having an amino substituent at the 2-position, an oxo substituent at the 5-position and an isopropyl substituent at the 7-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "041)] was the most effective in reducing the pain score followed by Amlexanox [MD, -2." | 5.41 | COMPARATIVE EFFICACY OF THERAPEUTIC INTERVENTIONS FOR THE MANAGEMENT OF RECURRENT APHTHOUS ULCERS: A SYSTEMATIC REVIEW AND NETWORK META-ANALYSIS. ( Cheng, YO; Gopinath, D; Shetty, NY; Syeed, MS; Veettil, SK, 2023) |
| "Amlexanox oral adhesive tablets are effective and safe in reducing aphthous ulcer pain and lesion size, as well as erythema and exudation in this Chinese cohort." | 5.12 | An evaluation on the efficacy and safety of amlexanox oral adhesive tablets in the treatment of recurrent minor aphthous ulceration in a Chinese cohort: a randomized, double-blind, vehicle-controlled, unparallel multicenter clinical trial. ( Cai, Y; Chen, F; Chen, Q; Lin, M; Liu, J; Shi, J; Wang, Y; Wang, Z; Zeng, X; Zhang, Y; Zhou, H, 2006) |
| "Both amlexanox and LLLT were equally effective in relieving pain associated with minor aphthous stomatitis." | 2.82 | Low-level laser therapy versus 5% amlexanox: a comparison of treatment effects in a cohort of patients with minor aphthous ulcers. ( Anjana, R; Jaishankar, HP; Jijin, MJ; Kavitha, AP; Krupashankar, R; Pai, J; Rakaraddi, M; Shobha, R, 2016) |
| "Amlexanox has been developed as a 5 percent topical oral paste for the treatment of patients with recurrent aphthous stomatitis (RAS) in most European countries." | 2.74 | A clinical evaluation of amlexanox oral adhesive pellicles in the treatment of recurrent aphthous stomatitis and comparison with amlexanox oral tablets: a randomized, placebo controlled, blinded, multicenter clinical trial. ( Chen, Q; Chen, R; Dong, Y; Gao, F; Jiang, L; Lin, M; Liu, J; Meng, W; Wang, Z; Xu, T; Zeng, X; Zhong, X; Zhou, H, 2009) |
| " Minimal adverse experiences were observed with the 991 subjects that were exposed to 5% Amlexanox paste." | 2.68 | 5% amlexanox oral paste, a new treatment for recurrent minor aphthous ulcers: II. Pharmacokinetics and demonstration of clinical safety. ( Alfano, MC; Charney, MR; Khandwala, A; Van Inwegen, RG, 1997) |
| "Levamisole has shown variable efficacy in reducing ulcer frequency and duration in patients with minor RAU." | 2.41 | Treatment strategies for recurrent oral aphthous ulcers. ( Barrons, RW, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (23.53) | 18.2507 |
| 2000's | 9 (52.94) | 29.6817 |
| 2010's | 3 (17.65) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Cheng, YO | 1 |
| Veettil, SK | 1 |
| Syeed, MS | 1 |
| Shetty, NY | 1 |
| Gopinath, D | 1 |
| Jijin, MJ | 1 |
| Rakaraddi, M | 1 |
| Pai, J | 1 |
| Jaishankar, HP | 1 |
| Krupashankar, R | 1 |
| Kavitha, AP | 1 |
| Anjana, R | 1 |
| Shobha, R | 1 |
| Pentapati, KC | 1 |
| Smriti, K | 1 |
| Gadicherla, S | 1 |
| Höger, P | 1 |
| Meng, W | 1 |
| Dong, Y | 1 |
| Liu, J | 2 |
| Wang, Z | 2 |
| Zhong, X | 1 |
| Chen, R | 1 |
| Zhou, H | 2 |
| Lin, M | 2 |
| Jiang, L | 1 |
| Gao, F | 1 |
| Xu, T | 1 |
| Chen, Q | 2 |
| Zeng, X | 2 |
| Bailey, J | 1 |
| McCarthy, C | 1 |
| Smith, RF | 1 |
| Murray, B | 2 |
| McGuinness, N | 1 |
| Biagioni, P | 1 |
| Hyland, P | 1 |
| Lamey, PJ | 2 |
| Biagioni, PA | 1 |
| Cai, Y | 1 |
| Chen, F | 1 |
| Wang, Y | 1 |
| Shi, J | 1 |
| Zhang, Y | 1 |
| Rodríguez, M | 1 |
| Rubio, JA | 1 |
| Sanchez, R | 1 |
| Burgess, JA | 1 |
| van der Ven, PF | 1 |
| Martin, M | 1 |
| Sherman, J | 1 |
| Haley, J | 1 |
| Greer, RO | 1 |
| Lindenmuth, JE | 1 |
| Juarez, T | 1 |
| Khandwala, A | 4 |
| Van Inwegen, RG | 2 |
| Charney, MR | 1 |
| Alfano, MC | 2 |
| Binnie, WH | 1 |
| Curro, FA | 1 |
| Van Inwegan, RG | 1 |
| Barrons, RW | 1 |
| Eisen, D | 1 |
| Lynch, DP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Nonaromatic Naphthalan - Composition Study and Biological Effects on Epithelial Tissues[NCT02920658] | Phase 2 | 57 participants (Actual) | Interventional | 2010-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for amlexanox and Aphthae
| Article | Year |
|---|---|
COMPARATIVE EFFICACY OF THERAPEUTIC INTERVENTIONS FOR THE MANAGEMENT OF RECURRENT APHTHOUS ULCERS: A SYSTEMATIC REVIEW AND NETWORK META-ANALYSIS.
Topics: Aminopyridines; Humans; Network Meta-Analysis; Pain; Stomatitis, Aphthous | 2023 |
Clinical inquiry. What is the most effective way to treat recurrent canker sores?
Topics: Administration, Topical; Aminopyridines; Anti-Allergic Agents; Anti-Infective Agents, Local; Anti-In | 2011 |
Review of over-the-counter treatments for aphthous ulceration and results from use of a dissolving oral patch containing glycyrrhiza complex herbal extract.
Topics: Aminopyridines; Anesthetics, Local; Cyanoacrylates; Glycyrrhiza; Hematinics; Humans; Mouthwashes; No | 2008 |
Treatment strategies for recurrent oral aphthous ulcers.
Topics: Adjuvants, Immunologic; Administration, Topical; Adrenal Cortex Hormones; Aminopyridines; Anti-Infla | 2001 |
Selecting topical and systemic agents for recurrent aphthous stomatitis.
Topics: Administration, Topical; Aminopyridines; Anti-Inflammatory Agents; Humans; Prednisone; Recurrence; S | 2001 |
10 trials available for amlexanox and Aphthae
| Article | Year |
|---|---|
Low-level laser therapy versus 5% amlexanox: a comparison of treatment effects in a cohort of patients with minor aphthous ulcers.
Topics: Adolescent; Adult; Aminopyridines; Anti-Allergic Agents; Female; Humans; India; Low-Level Light Ther | 2016 |
A clinical evaluation of amlexanox oral adhesive pellicles in the treatment of recurrent aphthous stomatitis and comparison with amlexanox oral tablets: a randomized, placebo controlled, blinded, multicenter clinical trial.
Topics: Adhesiveness; Administration, Oral; Aminopyridines; Anti-Allergic Agents; China; Double-Blind Method | 2009 |
A comparative study of the efficacy of Aphtheal in the management of recurrent minor aphthous ulceration.
Topics: Adult; Aminopyridines; Anti-Allergic Agents; Body Temperature; Erythema; Female; Humans; Male; Secon | 2005 |
The efficacy of amlexanox OraDisc on the prevention of recurrent minor aphthous ulceration.
Topics: Administration, Topical; Adult; Aminopyridines; Anti-Allergic Agents; Body Temperature; Double-Blind | 2006 |
An evaluation on the efficacy and safety of amlexanox oral adhesive tablets in the treatment of recurrent minor aphthous ulceration in a Chinese cohort: a randomized, double-blind, vehicle-controlled, unparallel multicenter clinical trial.
Topics: Adhesives; Adolescent; Adult; Aged; Aminopyridines; Anti-Allergic Agents; Cohort Studies; Double-Bli | 2006 |
Effectiveness of two oral pastes for the treatment of recurrent aphthous stomatitis.
Topics: Aminopyridines; Analysis of Variance; Anti-Allergic Agents; Anti-Inflammatory Agents; Clobetasol; Do | 2007 |
A double-blind study of topically applied 5% amlexanox in the treatment of aphthous ulcers.
Topics: Administration, Oral; Administration, Topical; Adolescent; Adult; Aged; Aminopyridines; Anti-Inflamm | 1993 |
5% amlexanox oral paste, a new treatment for recurrent minor aphthous ulcers: II. Pharmacokinetics and demonstration of clinical safety.
Topics: Administration, Topical; Adult; Aminopyridines; Anti-Inflammatory Agents; Area Under Curve; Dose-Res | 1997 |
5% amlexanox oral paste, a new treatment for recurrent minor aphthous ulcers: I. Clinical demonstration of acceleration of healing and resolution of pain.
Topics: Administration, Topical; Adult; Aminopyridines; Analysis of Variance; Anti-Inflammatory Agents; Dose | 1997 |
Amlexanox oral paste: a novel treatment that accelerates the healing of aphthous ulcers.
Topics: Administration, Topical; Adult; Aminopyridines; Anti-Inflammatory Agents; Chi-Square Distribution; D | 1997 |
2 other studies available for amlexanox and Aphthae
| Article | Year |
|---|---|
Low-level laser therapy versus 5% amlexanox: a comparison of treatment effects in a cohort of minor aphthous ulcers patients-a commentary.
Topics: Aminopyridines; Humans; Low-Level Light Therapy; Pain Measurement; Recurrence; Stomatitis, Aphthous | 2016 |
[Local Treatment of stomatitis aphthosa].
Topics: Administration, Topical; Aminopyridines; Anti-Allergic Agents; Humans; Stomatitis, Aphthous | 2008 |