amlexanox has been researched along with Acute Lung Injury in 2 studies
amlexanox: SRA-A antagonist;structure given in first source
amlexanox : A pyridochromene-derived monocarboxylic acid having an amino substituent at the 2-position, an oxo substituent at the 5-position and an isopropyl substituent at the 7-position.
Acute Lung Injury: A condition of lung damage that is characterized by bilateral pulmonary infiltrates (PULMONARY EDEMA) rich in NEUTROPHILS, and in the absence of clinical HEART FAILURE. This can represent a spectrum of pulmonary lesions, endothelial and epithelial, due to numerous factors (physical, chemical, or biological).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The specific mechanism of paraquat (PQ)-induced acute lung injury (ALI) is unclear, though inflammation is a likely contributor." | 7.96 | Inhibition of TBK1 by amlexanox attenuates paraquat-induced acute lung injury. ( Li, Y; Ma, Z; Wang, N; Wang, X; Wang, Y; Yuan, Y; Zhang, C; Zhao, M, 2020) |
| "The specific mechanism of paraquat (PQ)-induced acute lung injury (ALI) is unclear, though inflammation is a likely contributor." | 3.96 | Inhibition of TBK1 by amlexanox attenuates paraquat-induced acute lung injury. ( Li, Y; Ma, Z; Wang, N; Wang, X; Wang, Y; Yuan, Y; Zhang, C; Zhao, M, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Qi, J | 1 |
| Zhou, Z | 1 |
| Lim, CW | 1 |
| Kim, JW | 1 |
| Kim, B | 1 |
| Wang, N | 1 |
| Li, Y | 1 |
| Wang, X | 1 |
| Ma, Z | 1 |
| Wang, Y | 1 |
| Zhang, C | 1 |
| Yuan, Y | 1 |
| Zhao, M | 1 |
2 other studies available for amlexanox and Acute Lung Injury
| Article | Year |
|---|---|
Amlexanox ameliorates acetaminophen-induced acute liver injury by reducing oxidative stress in mice.
Topics: Acetaminophen; Acute Lung Injury; Aminopyridines; AMP-Activated Protein Kinases; Animals; Cells, Cul | 2019 |
Inhibition of TBK1 by amlexanox attenuates paraquat-induced acute lung injury.
Topics: Acute Lung Injury; Aminopyridines; Animals; Anti-Inflammatory Agents; Bronchoalveolar Lavage Fluid; | 2020 |