Page last updated: 2024-10-21

amitrole and Reperfusion Injury

amitrole has been researched along with Reperfusion Injury in 8 studies

Amitrole: A non-selective post-emergence, translocated herbicide. According to the Seventh Annual Report on Carcinogens (PB95-109781, 1994) this substance may reasonably be anticipated to be a carcinogen. (From Merck Index, 12th ed) It is an irreversible inhibitor of CATALASE, and thus impairs activity of peroxisomes.
amitrole : A member of the class of triazoles that is 1H-1,2,4-triazole substituted by an amino group at position 3. Used to control annual grasses and aquatic weeds (but not on food crops because it causes cancer in laboratory animals). Its use within the EU was banned from September 2017 on the grounds of potential groundwater contamination and risks to aquatic life; there have also been concerns about its endocrine-disrupting properties.

Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.

Research Excerpts

ExcerptRelevanceReference
"We investigated the influence of catalase and aminotriasol on reactions of the smooth muscle cells induced by angiotensin II (ANG II) after ischemia-reperfusion (I/R)."7.76Modulation of the reaction of vascular smooth muscle cells to angiotensin II induced by catalase and aminotriasol during ischemia-reperfusion. ( Grześk, G; Jasinski, M; Matusiak, G; Slupski, M; Szadujkis-Szadurska, K; Szadujkis-Szadurski, R, 2010)
"We investigated the influence of catalase and aminotriasol on reactions of the smooth muscle cells induced by angiotensin II (ANG II) after ischemia-reperfusion (I/R)."3.76Modulation of the reaction of vascular smooth muscle cells to angiotensin II induced by catalase and aminotriasol during ischemia-reperfusion. ( Grześk, G; Jasinski, M; Matusiak, G; Slupski, M; Szadujkis-Szadurska, K; Szadujkis-Szadurski, R, 2010)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's5 (62.50)18.2507
2000's1 (12.50)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Guo, HC1
Zhang, Z1
Zhang, LN1
Xiong, C1
Feng, C1
Liu, Q1
Liu, X1
Shi, XL1
Wang, YL1
Szadujkis-Szadurska, K1
Slupski, M1
Szadujkis-Szadurski, R1
Jasinski, M1
Grześk, G1
Matusiak, G1
Gulati, S1
Ainol, L1
Orak, J1
Singh, AK1
Singh, I1
Simonson, SG1
Zhang, J1
Canada, AT1
Su, YF1
Benveniste, H1
Piantadosi, CA1
Villa, P1
Carugo, C1
Guaitani, A1
Babbs, CF1
Salaris, SC1
Turek, JJ1
McCutchan, HJ1
Schwappach, JR1
Enquist, EG1
Walden, DL1
Terada, LS2
Reiss, OK1
Leff, JA1
Repine, JE2
Brown, JM1
Grosso, MA1
Whitman, GJ1
Velasco, SE1
Patt, A1
Harken, AH1

Other Studies

8 other studies available for amitrole and Reperfusion Injury

ArticleYear
Chronic intermittent hypobaric hypoxia protects the heart against ischemia/reperfusion injury through upregulation of antioxidant enzymes in adult guinea pigs.
    Acta pharmacologica Sinica, 2009, Volume: 30, Issue:7

    Topics: Amitrole; Animals; Antioxidants; Body Weight; Catalase; Enzyme Inhibitors; Guinea Pigs; Hydrogen Per

2009
Modulation of the reaction of vascular smooth muscle cells to angiotensin II induced by catalase and aminotriasol during ischemia-reperfusion.
    Transplantation proceedings, 2010, Volume: 42, Issue:5

    Topics: Amitrole; Angiotensin II; Animals; Arteries; Catalase; Ischemia; Male; Rats; Rats, Wistar; Reperfusi

2010
Alterations of peroxisomal function in ischemia-reperfusion injury of rat kidney.
    Biochimica et biophysica acta, 1993, Oct-20, Volume: 1182, Issue:3

    Topics: Acyl-CoA Oxidase; Amitrole; Animals; Carbon Radioisotopes; Catalase; Electron Transport Complex IV;

1993
Hydrogen peroxide production by monoamine oxidase during ischemia-reperfusion in the rat brain.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1993, Volume: 13, Issue:1

    Topics: Amitrole; Animals; Brain Ischemia; Catalase; Glutathione; Hydrogen Peroxide; Male; Monoamine Oxidase

1993
No evidence of intracellular oxidative stress during ischemia-reperfusion damage in rat liver in vivo.
    Toxicology letters, 1992, Volume: 61, Issue:2-3

    Topics: Alanine Transaminase; Amitrole; Animals; Aspartate Aminotransferases; Catalase; Ischemia; Liver; Mal

1992
Cytochemical studies of hydrogen peroxide generation in postischemic hepatocytes.
    The American journal of physiology, 1991, Volume: 260, Issue:1 Pt 2

    Topics: Amitrole; Animals; Histocytochemistry; Hydrogen Peroxide; Ischemia; Liver; Liver Diseases; Male; Mic

1991
Xanthine oxidase-derived H2O2 contributes to reperfusion injury of ischemic skeletal muscle.
    The American journal of physiology, 1990, Volume: 258, Issue:5 Pt 2

    Topics: Allopurinol; Amitrole; Animals; Catalase; Hydrogen Peroxide; Ischemia; Male; Muscle Contraction; Mus

1990
Hydrogen peroxide mediates reperfusion injury in the isolated rat heart.
    Molecular and cellular biochemistry, 1988, Volume: 84, Issue:2

    Topics: Amitrole; Animals; Catalase; Coronary Circulation; Heart; Hydrogen Peroxide; In Vitro Techniques; My

1988