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amitrole and Precancerous Conditions

amitrole has been researched along with Precancerous Conditions in 1 studies

Amitrole: A non-selective post-emergence, translocated herbicide. According to the Seventh Annual Report on Carcinogens (PB95-109781, 1994) this substance may reasonably be anticipated to be a carcinogen. (From Merck Index, 12th ed) It is an irreversible inhibitor of CATALASE, and thus impairs activity of peroxisomes.
amitrole : A member of the class of triazoles that is 1H-1,2,4-triazole substituted by an amino group at position 3. Used to control annual grasses and aquatic weeds (but not on food crops because it causes cancer in laboratory animals). Its use within the EU was banned from September 2017 on the grounds of potential groundwater contamination and risks to aquatic life; there have also been concerns about its endocrine-disrupting properties.

Precancerous Conditions: Pathological conditions that tend eventually to become malignant.

Research Excerpts

ExcerptRelevanceReference
"Amitrole was administered to mice in drinking water at a dose of 1% for 6 months."1.27Amitrole: strain differences in morphological response of the liver following subchronic administration to mice. ( Hayashi, Y; Makino, S; Mori, S; Ohhara, T; Takeuchi, Y; Tochino, Y; Toyama, M, 1985)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mori, S1
Takeuchi, Y1
Toyama, M1
Makino, S1
Ohhara, T1
Tochino, Y1
Hayashi, Y1

Other Studies

1 other study available for amitrole and Precancerous Conditions

ArticleYear
Amitrole: strain differences in morphological response of the liver following subchronic administration to mice.
    Toxicology letters, 1985, Volume: 29, Issue:2-3

    Topics: Amitrole; Animals; Female; Hyperplasia; Immunity, Cellular; Liver; Liver Neoplasms, Experimental; Mi

1985