amitrole has been researched along with Nephrosis in 2 studies
Amitrole: A non-selective post-emergence, translocated herbicide. According to the Seventh Annual Report on Carcinogens (PB95-109781, 1994) this substance may reasonably be anticipated to be a carcinogen. (From Merck Index, 12th ed) It is an irreversible inhibitor of CATALASE, and thus impairs activity of peroxisomes.
amitrole : A member of the class of triazoles that is 1H-1,2,4-triazole substituted by an amino group at position 3. Used to control annual grasses and aquatic weeds (but not on food crops because it causes cancer in laboratory animals). Its use within the EU was banned from September 2017 on the grounds of potential groundwater contamination and risks to aquatic life; there have also been concerns about its endocrine-disrupting properties.
Nephrosis: Pathological processes of the KIDNEY without inflammatory or neoplastic components. Nephrosis may be a primary disorder or secondary complication of other diseases. It is characterized by the NEPHROTIC SYNDROME indicating the presence of PROTEINURIA and HYPOALBUMINEMIA with accompanying EDEMA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Reactive oxygen species have been involved in the pathophysiology of puromycin aminonucleoside (PAN)-nephrosis." | 3.70 | Effect of the in vivo catalase inhibition on aminonucleoside nephrosis. ( Granados-Silvestre, MD; Hernández-Pando, R; Medina-Campos, ON; Pedraza-Chaverri, J, 1999) |
| "Glomerular epithelial cell injury is thought to be the primary reason for the development of proteinuria in puromycin aminonucleoside nephrosis (PAN), the rat model of nephrotic syndrome." | 3.69 | Puromycin aminonucleoside inhibits mesangial cell-induced contraction of collagen gels by stimulating production of reactive oxygen species. ( Ailenberg, M; Downey, GP; Silverman, M; Waddell, TK; Zent, R, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zent, R | 1 |
| Ailenberg, M | 1 |
| Waddell, TK | 1 |
| Downey, GP | 1 |
| Silverman, M | 1 |
| Pedraza-Chaverri, J | 1 |
| Granados-Silvestre, MD | 1 |
| Medina-Campos, ON | 1 |
| Hernández-Pando, R | 1 |
2 other studies available for amitrole and Nephrosis
| Article | Year |
|---|---|
Puromycin aminonucleoside inhibits mesangial cell-induced contraction of collagen gels by stimulating production of reactive oxygen species.
Topics: Amitrole; Animals; Catalase; Collagen; Culture Techniques; Disease Models, Animal; Extracellular Mat | 1995 |
Effect of the in vivo catalase inhibition on aminonucleoside nephrosis.
Topics: Amitrole; Animals; Catalase; Disease Progression; Drug Evaluation, Preclinical; Enzyme Inhibitors; G | 1999 |