Page last updated: 2024-10-21

amitrole and Neoplasms

amitrole has been researched along with Neoplasms in 10 studies

Amitrole: A non-selective post-emergence, translocated herbicide. According to the Seventh Annual Report on Carcinogens (PB95-109781, 1994) this substance may reasonably be anticipated to be a carcinogen. (From Merck Index, 12th ed) It is an irreversible inhibitor of CATALASE, and thus impairs activity of peroxisomes.
amitrole : A member of the class of triazoles that is 1H-1,2,4-triazole substituted by an amino group at position 3. Used to control annual grasses and aquatic weeds (but not on food crops because it causes cancer in laboratory animals). Its use within the EU was banned from September 2017 on the grounds of potential groundwater contamination and risks to aquatic life; there have also been concerns about its endocrine-disrupting properties.

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19906 (60.00)18.7374
1990's0 (0.00)18.2507
2000's1 (10.00)29.6817
2010's2 (20.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Sang, Y1
Cao, F1
Li, W1
Zhang, L1
You, Y1
Deng, Q1
Dong, K1
Ren, J1
Qu, X1
Siu, M1
Pastor, R1
Liu, W1
Barrett, K1
Berry, M1
Blair, WS1
Chang, C1
Chen, JZ1
Eigenbrot, C1
Ghilardi, N1
Gibbons, P1
He, H1
Hurley, CA1
Kenny, JR1
Cyrus Khojasteh, S1
Le, H1
Lee, L1
Lyssikatos, JP1
Magnuson, S1
Pulk, R1
Tsui, V1
Ultsch, M1
Xiao, Y1
Zhu, BY1
Sampath, D1
Oh, SH1
Kim, YS1
Lim, SC1
Hou, YF1
Chang, IY1
You, HJ1
THOMSON, JF1
KLIPFEL, FJ1
FEINSTEIN, RN1
DAINKO, JL1
HOZUMI, M1
SUGIMURA, T1
Sharp, DS1
Eskenazi, B1
Harrison, R1
Callas, P1
Smith, AH1
Axelson, O2
Sundell, L2
Rehn, M1

Reviews

1 review available for amitrole and Neoplasms

ArticleYear
Delayed health hazards of pesticide exposure.
    Annual review of public health, 1986, Volume: 7

    Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Agent Orange; Agricultural Worker

1986

Other Studies

9 other studies available for amitrole and Neoplasms

ArticleYear
Bioinspired Construction of a Nanozyme-Based H
    Journal of the American Chemical Society, 2020, 03-18, Volume: 142, Issue:11

    Topics: Amitrole; Animals; Antineoplastic Agents; Catalase; Catalysis; Cell Line, Tumor; Drug Therapy; Enzym

2020
2-Amino-[1,2,4]triazolo[1,5-a]pyridines as JAK2 inhibitors.
    Bioorganic & medicinal chemistry letters, 2013, Sep-01, Volume: 23, Issue:17

    Topics: Amitrole; Animals; Antineoplastic Agents; Crystallography, X-Ray; Humans; Janus Kinase 2; Mice; Mode

2013
Dihydrocapsaicin (DHC), a saturated structural analog of capsaicin, induces autophagy in human cancer cells in a catalase-regulated manner.
    Autophagy, 2008, Volume: 4, Issue:8

    Topics: Adenine; Amitrole; Apoptosis; Autophagy; Autophagy-Related Protein 5; Capsaicin; Caspase 3; Catalase

2008
Amitrole.
    Report on carcinogens : carcinogen profiles, 2011, Volume: 12

    Topics: Amitrole; Animals; Carcinogens; Enzyme Inhibitors; Herbicides; Humans; Neoplasms

2011
Intracellular distribution of uricase and catalase in livers of tumor-bearing mice and mice given injections of aminotriazole.
    Cancer research, 1958, Volume: 18, Issue:2

    Topics: Amitrole; Animals; Azoles; Catalase; Cytoplasm; Injections; Liver; Mice; Neoplasms; Oxidoreductases;

1958
Use of 3-amino-1,2,4-triazole to reduce body catalase activity in cancer studies.
    Cancer research, 1959, Volume: 19, Issue:6, Part 1

    Topics: Amitrole; Antithyroid Agents; Azoles; Catalase; Neoplasms; Oxidation-Reduction; Triazoles

1959
Studies on the mechanism of catalase depression by toxohormone, with the aid of allylisopropylacetamide, allylisopropylacetylcarbamide, and 3-amino-1,2,4-triazole.
    Gan, 1962, Volume: 53

    Topics: Allylisopropylacetamide; Amides; Amitrole; Azoles; Catalase; Depression; Depressive Disorder; Endoto

1962
Herbicide exposure, mortality and tumor incidence. An epidemiological investigation on Swedish railroad workers.
    Work, environment, health, 1974, Volume: 11, Issue:1

    Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Amitrole; Environmental Exposure;

1974
[Exposure to herbicides--mortality and tumor incidence. An epidemiologie investigation of Swedish railroad workers].
    Lakartidningen, 1974, Jun-12, Volume: 71, Issue:24

    Topics: Amitrole; Herbicides; Humans; Lung Neoplasms; Male; Neoplasms; Occupational Diseases; Railroads; Res

1974