amitrole has been researched along with Mesothelioma in 2 studies
Amitrole: A non-selective post-emergence, translocated herbicide. According to the Seventh Annual Report on Carcinogens (PB95-109781, 1994) this substance may reasonably be anticipated to be a carcinogen. (From Merck Index, 12th ed) It is an irreversible inhibitor of CATALASE, and thus impairs activity of peroxisomes.
amitrole : A member of the class of triazoles that is 1H-1,2,4-triazole substituted by an amino group at position 3. Used to control annual grasses and aquatic weeds (but not on food crops because it causes cancer in laboratory animals). Its use within the EU was banned from September 2017 on the grounds of potential groundwater contamination and risks to aquatic life; there have also been concerns about its endocrine-disrupting properties.
Mesothelioma: A tumor derived from mesothelial tissue (peritoneum, pleura, pericardium). It appears as broad sheets of cells, with some regions containing spindle-shaped, sarcoma-like cells and other regions showing adenomatous patterns. Pleural mesotheliomas have been linked to exposure to asbestos. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Malignant mesothelioma is a resistant tumor with high levels of manganese superoxide dismutase, a central superoxide scavenging AOE." | 1.31 | Expression and prognostic significance of catalase in malignant mesothelioma. ( Kaarteenaho-Wiik, R; Kahlos, K; Kinnula, VL; Linnainmaa, K; Pääkkö, P; Soini, Y; Sormunen, R, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kahlos, K | 2 |
| Pitkänen, S | 1 |
| Hassinen, I | 1 |
| Linnainmaa, K | 2 |
| Kinnula, VL | 2 |
| Soini, Y | 1 |
| Sormunen, R | 1 |
| Kaarteenaho-Wiik, R | 1 |
| Pääkkö, P | 1 |
2 other studies available for amitrole and Mesothelioma
| Article | Year |
|---|---|
Generation of reactive oxygen species by human mesothelioma cells.
Topics: Amitrole; Buthionine Sulfoximine; Citrate (si)-Synthase; Electron Transport Complex IV; Humans; Meso | 1999 |
Expression and prognostic significance of catalase in malignant mesothelioma.
Topics: Amitrole; Biomarkers, Tumor; Blotting, Western; Catalase; Epirubicin; Humans; Immunohistochemistry; | 2001 |