amitrole has been researched along with Hyperplasia in 8 studies
Amitrole: A non-selective post-emergence, translocated herbicide. According to the Seventh Annual Report on Carcinogens (PB95-109781, 1994) this substance may reasonably be anticipated to be a carcinogen. (From Merck Index, 12th ed) It is an irreversible inhibitor of CATALASE, and thus impairs activity of peroxisomes.
amitrole : A member of the class of triazoles that is 1H-1,2,4-triazole substituted by an amino group at position 3. Used to control annual grasses and aquatic weeds (but not on food crops because it causes cancer in laboratory animals). Its use within the EU was banned from September 2017 on the grounds of potential groundwater contamination and risks to aquatic life; there have also been concerns about its endocrine-disrupting properties.
Hyperplasia: An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Amitrole was administered to mice in drinking water at a dose of 1% for 6 months." | 1.27 | Amitrole: strain differences in morphological response of the liver following subchronic administration to mice. ( Hayashi, Y; Makino, S; Mori, S; Ohhara, T; Takeuchi, Y; Tochino, Y; Toyama, M, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (62.50) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hoshi, S | 1 |
| Hoshi, N | 1 |
| Okamoto, M | 1 |
| Paiz, J | 1 |
| Kusakabe, T | 1 |
| Ward, JM | 1 |
| Kimura, S | 1 |
| Joddar, B | 1 |
| Reen, RK | 1 |
| Firstenberg, MS | 1 |
| Varadharaj, S | 1 |
| McCord, JM | 1 |
| Zweier, JL | 1 |
| Gooch, KJ | 1 |
| Wynford-Thomas, D | 2 |
| Stringer, BM | 2 |
| Williams, ED | 1 |
| Tsuda, H | 1 |
| Hananouchi, M | 1 |
| Tatematsu, M | 1 |
| Hirose, M | 1 |
| Hirao, K | 1 |
| Groch, KM | 1 |
| Clifton, KH | 1 |
| Mori, S | 1 |
| Takeuchi, Y | 1 |
| Toyama, M | 1 |
| Makino, S | 1 |
| Ohhara, T | 1 |
| Tochino, Y | 1 |
| Hayashi, Y | 1 |
| Gaines, TB | 1 |
| Kimbrough, RD | 1 |
| Linder, RE | 1 |
8 other studies available for amitrole and Hyperplasia
| Article | Year |
|---|---|
Role of NKX2-1 in N-bis(2-hydroxypropyl)-nitrosamine-induced thyroid adenoma in mice.
Topics: Adenoma; Amitrole; Animals; Carcinogens; Female; Genes, ras; Hyperplasia; Male; Mice; Nitrosamines; | 2009 |
Protandim attenuates intimal hyperplasia in human saphenous veins cultured ex vivo via a catalase-dependent pathway.
Topics: Amitrole; Antioxidants; Blotting, Western; Catalase; Cell Proliferation; Drugs, Chinese Herbal; Endo | 2011 |
Circadian rhythm of mitotic activity in normal and hyperplastic rat thyroid.
Topics: Amitrole; Animals; Circadian Rhythm; Hyperplasia; Male; Mitosis; Rats; Rats, Inbred Strains; Thyroid | 1982 |
Mast cell hyperplasia during goitrogen-induced thyroid growth - a quantitative study.
Topics: Amitrole; Animals; Cell Count; Hyperplasia; Male; Mast Cells; Organ Size; Rats; Rats, Inbred Strains | 1982 |
Tumorigenic effect of 3-amino-1H-1,2,4-triazole on rat thyroid.
Topics: Amitrole; Animals; Cystadenoma; Female; Goiter; Hyperplasia; Neoplasms, Experimental; Rats; Thyroid | 1976 |
The effects of goitrogenesis, involution, and goitrogenic rechallenge on the clonogenic cell content of the rat thyroid.
Topics: Amitrole; Animals; Cell Division; Chlorates; Clone Cells; DNA; Goiter; Hyperplasia; Male; Rats; Rats | 1992 |
Amitrole: strain differences in morphological response of the liver following subchronic administration to mice.
Topics: Amitrole; Animals; Female; Hyperplasia; Immunity, Cellular; Liver; Liver Neoplasms, Experimental; Mi | 1985 |
The toxicity of amitrole in the rat.
Topics: Amitrole; Animals; Body Weight; Diet; Female; Herbicides; Hyperplasia; Intubation, Gastrointestinal; | 1973 |