Page last updated: 2024-10-21

amitrole and Hepatocellular Carcinoma

amitrole has been researched along with Hepatocellular Carcinoma in 4 studies

Amitrole: A non-selective post-emergence, translocated herbicide. According to the Seventh Annual Report on Carcinogens (PB95-109781, 1994) this substance may reasonably be anticipated to be a carcinogen. (From Merck Index, 12th ed) It is an irreversible inhibitor of CATALASE, and thus impairs activity of peroxisomes.
amitrole : A member of the class of triazoles that is 1H-1,2,4-triazole substituted by an amino group at position 3. Used to control annual grasses and aquatic weeds (but not on food crops because it causes cancer in laboratory animals). Its use within the EU was banned from September 2017 on the grounds of potential groundwater contamination and risks to aquatic life; there have also been concerns about its endocrine-disrupting properties.

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's1 (25.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zheng, QS1
Zhang, YT1
Zheng, RL1
Chovolou, Y1
Watjen, W1
Kampkotter, A1
Kahl, R1
Vesselinovitch, SD1
Fandrey, J1
Frede, S1
Jelkmann, W1

Other Studies

4 other studies available for amitrole and Hepatocellular Carcinoma

ArticleYear
Ascorbic acid induces redifferentiation and growth inhibition in human hepatoma cells by increasing endogenous hydrogen peroxide.
    Die Pharmazie, 2002, Volume: 57, Issue:11

    Topics: alpha-Fetoproteins; Amitrole; Antioxidants; Ascorbic Acid; Carcinoma, Hepatocellular; Cell Different

2002
Resistance to tumor necrosis factor-alpha (TNF-alpha)-induced apoptosis in rat hepatoma cells expressing TNF-alpha is linked to low antioxidant enzyme expression.
    The Journal of biological chemistry, 2003, Aug-08, Volume: 278, Issue:32

    Topics: Amitrole; Animals; Antioxidants; Apoptosis; Blotting, Northern; Blotting, Western; Carcinoma, Hepato

2003
Perinatal hepatocarcinogenesis.
    Biological research in pregnancy and perinatology, 1983, Volume: 4, Issue:1

    Topics: Age Factors; Amitrole; Animals; Animals, Newborn; Carcinogens; Carcinoma, Hepatocellular; Female; Ge

1983
Role of hydrogen peroxide in hypoxia-induced erythropoietin production.
    The Biochemical journal, 1994, Oct-15, Volume: 303 ( Pt 2)

    Topics: Amitrole; Base Sequence; Carcinoma, Hepatocellular; Catalase; DNA Primers; Dose-Response Relationshi

1994