amitrole and Goiter
amitrole has been researched along with Goiter in 8 studies
Amitrole: A non-selective post-emergence, translocated herbicide. According to the Seventh Annual Report on Carcinogens (PB95-109781, 1994) this substance may reasonably be anticipated to be a carcinogen. (From Merck Index, 12th ed) It is an irreversible inhibitor of CATALASE, and thus impairs activity of peroxisomes.
amitrole : A member of the class of triazoles that is 1H-1,2,4-triazole substituted by an amino group at position 3. Used to control annual grasses and aquatic weeds (but not on food crops because it causes cancer in laboratory animals). Its use within the EU was banned from September 2017 on the grounds of potential groundwater contamination and risks to aquatic life; there have also been concerns about its endocrine-disrupting properties.
Goiter: Enlargement of the THYROID GLAND that may increase from about 20 grams to hundreds of grams in human adults. Goiter is observed in individuals with normal thyroid function (euthyroidism), thyroid deficiency (HYPOTHYROIDISM), or hormone overproduction (HYPERTHYROIDISM). Goiter may be congenital or acquired, sporadic or endemic (GOITER, ENDEMIC).
Research
Studies (8)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Freyberger, A | 1 |
| Ahr, HJ | 1 |
| Wynford-Thomas, D | 1 |
| Stringer, BM | 1 |
| Harach, HR | 1 |
| Williams, ED | 1 |
| Marinò, M | 1 |
| Chiovato, L | 1 |
| Mitsiades, N | 1 |
| Latrofa, F | 1 |
| Andrews, D | 1 |
| Tseleni-Balafouta, S | 1 |
| Collins, AB | 1 |
| Pinchera, A | 1 |
| McCluskey, RT | 1 |
| Tsuda, H | 1 |
| Hananouchi, M | 1 |
| Tatematsu, M | 1 |
| Hirose, M | 1 |
| Hirao, K | 1 |
| Groch, KM | 2 |
| Clifton, KH | 2 |
| Smith, AG | 1 |
| Dinsdale, D | 1 |
| Cabral, JR | 1 |
| Wright, AL | 1 |
| Cartier, LJ | 1 |
| Williams, IK | 1 |
| Holloszy, J | 1 |
| Premachandra, BN | 1 |
Trials
1 trial available for amitrole and Goiter
| Article | Year |
|---|---|
Circulating thyroglobulin transcytosed by thyroid cells in complexed with secretory components of its endocytic receptor megalin.
Topics: Adult; Aged; Amitrole; Animals; Autoantigens; Blotting, Western; Cells, Cultured; Epithelial Cells; | 2000 |
Other Studies
7 other studies available for amitrole and Goiter
| Article | Year |
|---|---|
Studies on the goitrogenic mechanism of action of N,N,N',N'-tetramethylthiourea.
Topics: Amitrole; Animals; Antithyroid Agents; Chromatography, High Pressure Liquid; Dose-Response Relations | 2006 |
Investigation of putative control mechanisms for thyroid growth.
Topics: Amitrole; Animals; Goiter; Male; Organ Size; Rats; Regeneration; Thyroid Gland; Thyroidectomy; Thyro | 1982 |
Tumorigenic effect of 3-amino-1H-1,2,4-triazole on rat thyroid.
Topics: Amitrole; Animals; Cystadenoma; Female; Goiter; Hyperplasia; Neoplasms, Experimental; Rats; Thyroid | 1976 |
The effects of goitrogenesis, involution, and goitrogenic rechallenge on the clonogenic cell content of the rat thyroid.
Topics: Amitrole; Animals; Cell Division; Chlorates; Clone Cells; DNA; Goiter; Hyperplasia; Male; Rats; Rats | 1992 |
The plateau phase rat goiter contains a sub-population of TSH-responsive follicular cells capable of proliferation following transplantation.
Topics: Amitrole; Animals; Cell Division; Chlorates; Goiter; Male; Rats; Rats, Inbred F344; Thyroid Gland; T | 1992 |
Goitre and wasting induced in hamsters by hexachlorobenzene.
Topics: Adipose Tissue; Amitrole; Animals; Chlorobenzenes; Cricetinae; Dealkylation; Goiter; Hexachlorobenze | 1987 |
Potentiation of thyroxine 5-deiodination by aminotriazole.
Topics: Amitrole; Animals; Goiter; Iodine; Male; Rats; Rats, Inbred Strains; Thyroxine; Triazoles; Triiodoth | 1985 |