amitrole has been researched along with Cell Transformation, Neoplastic in 3 studies
Amitrole: A non-selective post-emergence, translocated herbicide. According to the Seventh Annual Report on Carcinogens (PB95-109781, 1994) this substance may reasonably be anticipated to be a carcinogen. (From Merck Index, 12th ed) It is an irreversible inhibitor of CATALASE, and thus impairs activity of peroxisomes.
amitrole : A member of the class of triazoles that is 1H-1,2,4-triazole substituted by an amino group at position 3. Used to control annual grasses and aquatic weeds (but not on food crops because it causes cancer in laboratory animals). Its use within the EU was banned from September 2017 on the grounds of potential groundwater contamination and risks to aquatic life; there have also been concerns about its endocrine-disrupting properties.
Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tsutsui, T | 1 |
| Maizumi, H | 1 |
| Barrett, JC | 1 |
| Inoue, K | 1 |
| Katoh, Y | 1 |
| Takayama, S | 1 |
| Mikalsen, SO | 1 |
| Kaalhus, O | 1 |
| Reith, A | 1 |
| Sanner, T | 1 |
3 other studies available for amitrole and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Amitrole-induced cell transformation and gene mutations in Syrian hamster embryo cells in culture.
Topics: Amitrole; Animals; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Mesocricetus; Mutat | 1984 |
In vitro transformation of hamster embryo cells by 3-(N-salicyloyl)amino-1,2,4-triazole.
Topics: Amitrole; Animals; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Embryo | 1981 |
Role of catalase and oxidative stress in hepatic peroxisome proliferator-induced morphological transformation of Syrian hamster embryo cells.
Topics: Amitrole; Animals; Catalase; Cell Line, Transformed; Cell Transformation, Neoplastic; Cells, Culture | 1990 |