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amitrole and Carbon Tetrachloride Poisoning

amitrole has been researched along with Carbon Tetrachloride Poisoning in 7 studies

Amitrole: A non-selective post-emergence, translocated herbicide. According to the Seventh Annual Report on Carcinogens (PB95-109781, 1994) this substance may reasonably be anticipated to be a carcinogen. (From Merck Index, 12th ed) It is an irreversible inhibitor of CATALASE, and thus impairs activity of peroxisomes.
amitrole : A member of the class of triazoles that is 1H-1,2,4-triazole substituted by an amino group at position 3. Used to control annual grasses and aquatic weeds (but not on food crops because it causes cancer in laboratory animals). Its use within the EU was banned from September 2017 on the grounds of potential groundwater contamination and risks to aquatic life; there have also been concerns about its endocrine-disrupting properties.

Carbon Tetrachloride Poisoning: Poisoning that results from ingestion, injection, inhalation, or skin absorption of CARBON TETRACHLORIDE.

Research Excerpts

ExcerptRelevanceReference
" In vivo studies from our laboratory with potent antioxidants in dosage regimes inhibiting LP, however, were in contrast with that hypothesis."1.29Depression of liver microsomal glucose 6-phosphatase activity in carbon tetrachloride-poisoned rats. Potential synergistic effects of lipid peroxidation and of covalent binding of haloalkane-derived free radicals to cellular components in the process. ( Castro, JA; de Toranzo, EG; González Padrón, A, 1996)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19906 (85.71)18.7374
1990's1 (14.29)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Matsumoto, Y1
Suga, T3
González Padrón, A1
de Toranzo, EG1
Castro, JA1
Ishii, H2
Ninobe, S2
Inatsu, Y1
Shapkina-Gun'ko, VA1
Leus, NF1
Drozhzhina, GI1
Traiger, GJ1
Plaa, GL1
Stenger, RJ1
Johnson, EA1

Other Studies

7 other studies available for amitrole and Carbon Tetrachloride Poisoning

ArticleYear
Protection by 3-amino-1,2,4-triazole against the lowered uptake of p-biphenylmethyl-(dl-tropyl-alpha-tropinium) bromide into the hepatic lysosomes of carbon tetrachloride-treated mice.
    Chemical & pharmaceutical bulletin, 1981, Volume: 29, Issue:12

    Topics: Amitrole; Animals; Carbon Tetrachloride Poisoning; Liver; Lysosomes; Male; Mice; Triazoles; Tropanes

1981
Depression of liver microsomal glucose 6-phosphatase activity in carbon tetrachloride-poisoned rats. Potential synergistic effects of lipid peroxidation and of covalent binding of haloalkane-derived free radicals to cellular components in the process.
    Free radical biology & medicine, 1996, Volume: 21, Issue:1

    Topics: Amitrole; Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Drug Synergism; Enzyme Inhi

1996
Effect of 3-amino-1,2,4-triazole treatment on catalase activity and triglyceride level in fatty liver of the rat.
    Biochemical pharmacology, 1977, Apr-01, Volume: 26, Issue:7

    Topics: Amitrole; Animals; Carbon Tetrachloride Poisoning; Catalase; Ethanol; Ethionine; Fatty Liver; Female

1977
Effect of 3-amino-1,2,4-triazole on carbon tetrachloride-induced necrosis.
    Chemical & pharmaceutical bulletin, 1977, Volume: 25, Issue:8

    Topics: Alanine Transaminase; Amitrole; Animals; Aspartate Aminotransferases; Carbon Tetrachloride Poisoning

1977
[Characteristics of the development of cataract models against a background of poisoning].
    Oftalmologicheskii zhurnal, 1989, Issue:2

    Topics: Amitrole; Animals; Carbon Tetrachloride Poisoning; Cataract; Disease Models, Animal; Free Radicals;

1989
Effect of aminotriazole on isopropanol- and acetone-induced potentiation of CCl 4 hepatotoxicity.
    Canadian journal of physiology and pharmacology, 1973, Volume: 51, Issue:4

    Topics: 1-Propanol; Acetone; Alanine Transaminase; Amitrole; Aniline Compounds; Animals; Carbon Tetrachlorid

1973
Modifying effect of 3-amino-1,2,4-triazole on phenobarbital-induced changes in rat liver.
    Experimental and molecular pathology, 1972, Volume: 16, Issue:2

    Topics: Amitrole; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cytochrom

1972