amitrole has been researched along with Brain Ischemia in 2 studies
Amitrole: A non-selective post-emergence, translocated herbicide. According to the Seventh Annual Report on Carcinogens (PB95-109781, 1994) this substance may reasonably be anticipated to be a carcinogen. (From Merck Index, 12th ed) It is an irreversible inhibitor of CATALASE, and thus impairs activity of peroxisomes.
amitrole : A member of the class of triazoles that is 1H-1,2,4-triazole substituted by an amino group at position 3. Used to control annual grasses and aquatic weeds (but not on food crops because it causes cancer in laboratory animals). Its use within the EU was banned from September 2017 on the grounds of potential groundwater contamination and risks to aquatic life; there have also been concerns about its endocrine-disrupting properties.
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Recent results demonstrate that cerebral ischemia of long duration, particularly when followed by reperfusion, leads to enhanced production of partially reduced oxygen species, notably hydrogen peroxide (H2O2)." | 1.28 | Free radical production and ischemic brain damage: influence of postischemic oxygen tension. ( Agardh, CD; Siesjö, BK; Smith, ML; Zhang, H, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Simonson, SG | 1 |
| Zhang, J | 1 |
| Canada, AT | 1 |
| Su, YF | 1 |
| Benveniste, H | 1 |
| Piantadosi, CA | 1 |
| Agardh, CD | 1 |
| Zhang, H | 1 |
| Smith, ML | 1 |
| Siesjö, BK | 1 |
2 other studies available for amitrole and Brain Ischemia
| Article | Year |
|---|---|
Hydrogen peroxide production by monoamine oxidase during ischemia-reperfusion in the rat brain.
Topics: Amitrole; Animals; Brain Ischemia; Catalase; Glutathione; Hydrogen Peroxide; Male; Monoamine Oxidase | 1993 |
Free radical production and ischemic brain damage: influence of postischemic oxygen tension.
Topics: Amitrole; Animals; Brain; Brain Ischemia; Catalase; Free Radicals; Histocytochemistry; Hydrogen Pero | 1991 |