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amitrole and Body Weight

amitrole has been researched along with Body Weight in 14 studies

Amitrole: A non-selective post-emergence, translocated herbicide. According to the Seventh Annual Report on Carcinogens (PB95-109781, 1994) this substance may reasonably be anticipated to be a carcinogen. (From Merck Index, 12th ed) It is an irreversible inhibitor of CATALASE, and thus impairs activity of peroxisomes.
amitrole : A member of the class of triazoles that is 1H-1,2,4-triazole substituted by an amino group at position 3. Used to control annual grasses and aquatic weeds (but not on food crops because it causes cancer in laboratory animals). Its use within the EU was banned from September 2017 on the grounds of potential groundwater contamination and risks to aquatic life; there have also been concerns about its endocrine-disrupting properties.

Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.

Research Excerpts

ExcerptRelevanceReference
" Measurements of 131I uptake by the thyroid gland, thyroid acinar cell height and protein-bound iodine failed to reveal an effect of theophylline in either control or hypothyroid animals although theophylline increased thyroid to body weight ratio in both groups."7.66Reversal by theophylline of some changes characteristically accompanying hypothyroidism in rats. ( Dasler, R; Fregly, MJ; Lutherer, LO; Tyler, PE, 1978)
" Measurements of 131I uptake by the thyroid gland, thyroid acinar cell height and protein-bound iodine failed to reveal an effect of theophylline in either control or hypothyroid animals although theophylline increased thyroid to body weight ratio in both groups."3.66Reversal by theophylline of some changes characteristically accompanying hypothyroidism in rats. ( Dasler, R; Fregly, MJ; Lutherer, LO; Tyler, PE, 1978)
"Hypo- and hyperthyroidism were induced in adult male rats, and the mRNA content of cocaine- and amphetamine-regulated transcript and agouti-related peptide was determined using in situ hybridization."1.31Thyroid status regulates CART but not AgRP mRNA levels in the rat hypothalamus. ( Diéguez, C; López, M; Señarís, RM; Seoane, L; Tovar, S, 2002)
"Hypothyroidism is associated with changes in renal function and a decrease in kidney weight."1.27Kidney structure in hypothyroidism. ( Davis, RG; Fregly, MJ; Madsen, KM; Tisher, CC, 1983)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19907 (50.00)18.7374
1990's0 (0.00)18.2507
2000's6 (42.86)29.6817
2010's1 (7.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jing, Y1
Wu, K1
Liu, J1
Ai, Q1
Ge, P1
Dai, J1
Jiang, R1
Zhou, D1
Che, Q1
Wan, J1
Zhang, L1
Guo, HC1
Zhang, Z1
Zhang, LN1
Xiong, C1
Feng, C1
Liu, Q1
Liu, X1
Shi, XL1
Wang, YL1
López, M1
Seoane, L1
Tovar, S1
Señarís, RM1
Diéguez, C1
Imai, T1
Onose, J1
Hasumura, M1
Takizawa, T1
Hirose, M1
Davis, RG1
Madsen, KM1
Fregly, MJ3
Tisher, CC1
Scammell, JG1
Karasu, C2
Pedraza-Chaverrí, J1
Granados-Silvestre, MD1
Medina-Campos, ON1
Maldonado, PD1
Olivares-Corichi, IM1
Ibarra-Rubio, ME1
Koçak, G1
Gotoh, M1
Griffin, C1
Hruban, Z1
Lutherer, LO1
Tyler, PE1
Dasler, R1
Sumi, C1
Yokoro, K1
Matsushima, R1
Tjälve, H1
Gaines, TB1
Kimbrough, RD1
Linder, RE1

Other Studies

14 other studies available for amitrole and Body Weight

ArticleYear
Aminotriazole alleviates acetaminophen poisoning via downregulating P450 2E1 and suppressing inflammation.
    PloS one, 2015, Volume: 10, Issue:4

    Topics: Amitrole; Animals; Body Weight; Catalase; Chemical and Drug Induced Liver Injury; Cytochrome P-450 C

2015
Chronic intermittent hypobaric hypoxia protects the heart against ischemia/reperfusion injury through upregulation of antioxidant enzymes in adult guinea pigs.
    Acta pharmacologica Sinica, 2009, Volume: 30, Issue:7

    Topics: Amitrole; Animals; Antioxidants; Body Weight; Catalase; Enzyme Inhibitors; Guinea Pigs; Hydrogen Per

2009
Thyroid status regulates CART but not AgRP mRNA levels in the rat hypothalamus.
    Neuroreport, 2002, Oct-07, Volume: 13, Issue:14

    Topics: Agouti-Related Protein; Amitrole; Animals; Appetite Regulation; Body Weight; Down-Regulation; Enzyme

2002
Indomethacin induces small intestinal damage and inhibits amitrole-associated thyroid carcinogenesis in rats initiated with N-bis(2-hydroxypropyl)nitrosamine.
    Toxicology letters, 2006, Jun-20, Volume: 164, Issue:1

    Topics: Amitrole; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Carcinogens; Cocarcinogenes

2006
Kidney structure in hypothyroidism.
    The American journal of pathology, 1983, Volume: 113, Issue:1

    Topics: Amitrole; Animals; Body Weight; Female; Glomerular Filtration Rate; Hypothyroidism; Kidney; Nephrons

1983
The effect of 3-amino-1,2,4-triazole on hepatic and renal deiodination of L-thyroxine to 3,5,3'-triiodothyronine.
    Toxicology and applied pharmacology, 1981, Volume: 60, Issue:1

    Topics: Amitrole; Animals; Biotransformation; Body Weight; Kidney; Liver; Male; Organ Size; Rats; Rats, Inbr

1981
Time course of changes in endothelium-dependent and -independent relaxation of chronically diabetic aorta: role of reactive oxygen species.
    European journal of pharmacology, 2000, Mar-31, Volume: 392, Issue:3

    Topics: Acetylcholine; Amitrole; Animals; Aorta, Thoracic; Blood Glucose; Body Weight; Catalase; Chronic Dis

2000
Post-transcriptional control of catalase expression in garlic-treated rats.
    Molecular and cellular biochemistry, 2001, Volume: 216, Issue:1-2

    Topics: Amitrole; Animals; Antioxidants; Blotting, Northern; Blotting, Western; Body Weight; Catalase; Creat

2001
Elimination of *O(2)(-)/H(2)O(2) by alpha-lipoic acid mediates the recovery of basal EDRF/NO availability and the reversal of superoxide dismutase-induced relaxation in diabetic rat aorta.
    Diabetes, obesity & metabolism, 2002, Volume: 4, Issue:1

    Topics: Amitrole; Animals; Aorta, Thoracic; Blood Glucose; Body Weight; Catalase; Diabetes Mellitus, Experim

2002
Effect of citrate and aminotriazole on matrical plates induced in hepatic microbodies.
    Virchows Archiv. B, Cell pathology, 1975, Volume: 17, Issue:4

    Topics: Amitrole; Animals; Aspirin; Body Weight; Carboxylic Acids; Catalase; Citrates; Clofibrate; Cycloprop

1975
Reversal by theophylline of some changes characteristically accompanying hypothyroidism in rats.
    Pharmacology, 1978, Volume: 17, Issue:1

    Topics: Amitrole; Animals; Blood Pressure; Body Weight; Diet; Drug Evaluation, Preclinical; Growth; Heart Ra

1978
Inhibition by 3-amino-1H-1,2,4-triazole of hepatic tumorigenesis induced by diethylstilbestrol alone or combined with N-nitrosobutylurea in WF rats.
    Journal of the National Cancer Institute, 1985, Volume: 74, Issue:6

    Topics: Amitrole; Animals; Body Weight; Diethylstilbestrol; Liver Neoplasms; Male; Nitrosourea Compounds; Or

1985
Fetal uptake and embryogenetic effects of aminotriazole in mice.
    Archives of toxicology, 1974, Volume: 33, Issue:1

    Topics: Administration, Oral; Amitrole; Animals; Autoradiography; Body Weight; Bone Marrow; Carbon Radioisot

1974
The toxicity of amitrole in the rat.
    Toxicology and applied pharmacology, 1973, Volume: 26, Issue:1

    Topics: Amitrole; Animals; Body Weight; Diet; Female; Herbicides; Hyperplasia; Intubation, Gastrointestinal;

1973