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amitrole and Autoimmune Thyroiditis

amitrole has been researched along with Autoimmune Thyroiditis in 2 studies

Amitrole: A non-selective post-emergence, translocated herbicide. According to the Seventh Annual Report on Carcinogens (PB95-109781, 1994) this substance may reasonably be anticipated to be a carcinogen. (From Merck Index, 12th ed) It is an irreversible inhibitor of CATALASE, and thus impairs activity of peroxisomes.
amitrole : A member of the class of triazoles that is 1H-1,2,4-triazole substituted by an amino group at position 3. Used to control annual grasses and aquatic weeds (but not on food crops because it causes cancer in laboratory animals). Its use within the EU was banned from September 2017 on the grounds of potential groundwater contamination and risks to aquatic life; there have also been concerns about its endocrine-disrupting properties.

Research Excerpts

ExcerptRelevanceReference
"In conclusion, autoimmune thyroiditis in an animal model can be prevented by reducing thyroidal iodine or its metabolism and optimal effects require intervention at the embryonic stage."1.28Uptake and metabolism of iodine is crucial for the development of thyroiditis in obese strain chickens. ( Bagchi, N; Brown, TR; Dhar, A; Sheth, D; Sundick, RS, 1991)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brown, TR1
Sundick, RS1
Dhar, A1
Sheth, D1
Bagchi, N1
Champion, BR1
Rayner, DC1
Byfield, PG1
Page, KR1
Chan, CT1
Roitt, IM1

Other Studies

2 other studies available for amitrole and Autoimmune Thyroiditis

ArticleYear
Uptake and metabolism of iodine is crucial for the development of thyroiditis in obese strain chickens.
    The Journal of clinical investigation, 1991, Volume: 88, Issue:1

    Topics: Amitrole; Animals; Chickens; Immunotherapy, Adoptive; Iodine; Obesity; Perchlorates; Potassium; Pota

1991
Critical role of iodination for T cell recognition of thyroglobulin in experimental murine thyroid autoimmunity.
    Journal of immunology (Baltimore, Md. : 1950), 1987, Dec-01, Volume: 139, Issue:11

    Topics: Amitrole; Animals; Autoantibodies; Epitopes; Humans; Iodide Peroxidase; Iodine; Male; Mice; Mice, In

1987