amitrole has been researched along with Anemia, Cooley's in 2 studies
Amitrole: A non-selective post-emergence, translocated herbicide. According to the Seventh Annual Report on Carcinogens (PB95-109781, 1994) this substance may reasonably be anticipated to be a carcinogen. (From Merck Index, 12th ed) It is an irreversible inhibitor of CATALASE, and thus impairs activity of peroxisomes.
amitrole : A member of the class of triazoles that is 1H-1,2,4-triazole substituted by an amino group at position 3. Used to control annual grasses and aquatic weeds (but not on food crops because it causes cancer in laboratory animals). Its use within the EU was banned from September 2017 on the grounds of potential groundwater contamination and risks to aquatic life; there have also been concerns about its endocrine-disrupting properties.
| Excerpt | Relevance | Reference |
|---|---|---|
| "While red cells from individuals with beta thalassemias are characterized by evidence of elevated in vivo oxidation, it has not been possible to directly examine the relationship between excess alpha-hemoglobin chains and the observed oxidant damage." | 1.29 | Effect of excess alpha-hemoglobin chains on cellular and membrane oxidation in model beta-thalassemic erythrocytes. ( Beuzard, Y; Hebbel, RP; Lubin, BH; Repka, T; Rouyer-Fessard, P; Scott, MD; van den Berg, JJ, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Scott, MD | 2 |
| van den Berg, JJ | 1 |
| Repka, T | 1 |
| Rouyer-Fessard, P | 1 |
| Hebbel, RP | 1 |
| Beuzard, Y | 1 |
| Lubin, BH | 1 |
2 other studies available for amitrole and Anemia, Cooley's
| Article | Year |
|---|---|
H2O2 injury in beta thalassemic erythrocytes: protective role of catalase and the prooxidant effects of GSH.
Topics: Amitrole; Animals; Azides; beta-Thalassemia; Catalase; Cell Survival; Erythrocytes; Glutathione; Hem | 2006 |
Effect of excess alpha-hemoglobin chains on cellular and membrane oxidation in model beta-thalassemic erythrocytes.
Topics: Amitrole; Antioxidants; beta-Thalassemia; Deferoxamine; Dextrans; Erythrocyte Deformability; Erythro | 1993 |