Page last updated: 2024-10-21

amitrole and Alloxan Diabetes

amitrole has been researched along with Alloxan Diabetes in 5 studies

Amitrole: A non-selective post-emergence, translocated herbicide. According to the Seventh Annual Report on Carcinogens (PB95-109781, 1994) this substance may reasonably be anticipated to be a carcinogen. (From Merck Index, 12th ed) It is an irreversible inhibitor of CATALASE, and thus impairs activity of peroxisomes.
amitrole : A member of the class of triazoles that is 1H-1,2,4-triazole substituted by an amino group at position 3. Used to control annual grasses and aquatic weeds (but not on food crops because it causes cancer in laboratory animals). Its use within the EU was banned from September 2017 on the grounds of potential groundwater contamination and risks to aquatic life; there have also been concerns about its endocrine-disrupting properties.

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's1 (20.00)18.2507
2000's2 (40.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ivanović-Matić, S1
Bogojević, D1
Martinović, V1
Petrović, A1
Jovanović-Stojanov, S1
Poznanović, G1
Grigorov, I1
Karasu, C3
Koçak, G1
Heikkila, RE1
Cohen, G1

Other Studies

5 other studies available for amitrole and Alloxan Diabetes

ArticleYear
Catalase inhibition in diabetic rats potentiates DNA damage and apoptotic cell death setting the stage for cardiomyopathy.
    Journal of physiology and biochemistry, 2014, Volume: 70, Issue:4

    Topics: Amitrole; Animals; Apoptosis; Catalase; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies;

2014
Increased activity of H2O2 in aorta isolated from chronically streptozotocin-diabetic rats: effects of antioxidant enzymes and enzymes inhibitors.
    Free radical biology & medicine, 1999, Volume: 27, Issue:1-2

    Topics: Amitrole; Animals; Antioxidants; Aorta; Catalase; Cyclooxygenase Inhibitors; Diabetes Mellitus, Expe

1999
Time course of changes in endothelium-dependent and -independent relaxation of chronically diabetic aorta: role of reactive oxygen species.
    European journal of pharmacology, 2000, Mar-31, Volume: 392, Issue:3

    Topics: Acetylcholine; Amitrole; Animals; Aorta, Thoracic; Blood Glucose; Body Weight; Catalase; Chronic Dis

2000
Elimination of *O(2)(-)/H(2)O(2) by alpha-lipoic acid mediates the recovery of basal EDRF/NO availability and the reversal of superoxide dismutase-induced relaxation in diabetic rat aorta.
    Diabetes, obesity & metabolism, 2002, Volume: 4, Issue:1

    Topics: Amitrole; Animals; Aorta, Thoracic; Blood Glucose; Body Weight; Catalase; Diabetes Mellitus, Experim

2002
Cytotoxic aspects of the interaction of ascorbic acid with alloxan and 6-hydroxydopamine.
    Annals of the New York Academy of Sciences, 1975, Sep-30, Volume: 258

    Topics: Alloxan; Amitrole; Animals; Ascorbic Acid; Binding Sites; Catalase; Chemical Phenomena; Chemistry; D

1975