amitrole has been researched along with Alcoholic Cardiomyopathy in 4 studies
Amitrole: A non-selective post-emergence, translocated herbicide. According to the Seventh Annual Report on Carcinogens (PB95-109781, 1994) this substance may reasonably be anticipated to be a carcinogen. (From Merck Index, 12th ed) It is an irreversible inhibitor of CATALASE, and thus impairs activity of peroxisomes.
amitrole : A member of the class of triazoles that is 1H-1,2,4-triazole substituted by an amino group at position 3. Used to control annual grasses and aquatic weeds (but not on food crops because it causes cancer in laboratory animals). Its use within the EU was banned from September 2017 on the grounds of potential groundwater contamination and risks to aquatic life; there have also been concerns about its endocrine-disrupting properties.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The morphologic features of alcoholic cardiomyopathy in human sudden death compared with those of experimental alcoholic cardiomyopathy (6 weeks of alcohol administration and simultaneous inhibition of catalase activity) proved to be nearly identical." | 1.27 | Ultrastructural and histochemical observations in human and experimental alcoholic cardiomyopathy. ( Cherpachenko, NM; Tsiplenkova, VG; Vikhert, AM, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kino, M | 1 |
| Bakeeva, LE | 1 |
| Skulachev, VP | 1 |
| Sudarikova, YV | 1 |
| Tsyplenkova, VG | 1 |
| Panchenko, LF | 1 |
| Antonenkov, VD | 1 |
| Tsiplenkova, VG | 1 |
| Vikhert, AM | 1 |
| Cherpachenko, NM | 1 |
4 other studies available for amitrole and Alcoholic Cardiomyopathy
| Article | Year |
|---|---|
Chronic effects of ethanol under partial inhibition of catalase activity in the rat heart: light and electron microscopic observations.
Topics: Alcoholism; Amitrole; Animals; Cardiomyopathy, Alcoholic; Catalase; Heart; Humans; Liver; Male; Micr | 1981 |
Mitochondria enter the nucleus (one further problem in chronic alcoholism).
Topics: Amitrole; Animals; Biopsy; Cardiomyopathy, Alcoholic; Cardiomyopathy, Hypertrophic; Cell Nucleus; Et | 2001 |
[Role of peroxisomal enzymes and lipid peroxidation in the pathogenesis of alcoholic cardiomyopathy].
Topics: Amitrole; Animals; Cardiomyopathy, Alcoholic; Disease Models, Animal; Ethanol; Heart; Lipid Peroxide | 1987 |
Ultrastructural and histochemical observations in human and experimental alcoholic cardiomyopathy.
Topics: Adult; Aged; Amitrole; Animals; Biopsy; Cardiomyopathy, Alcoholic; Cardiomyopathy, Dilated; Catalase | 1986 |