Page last updated: 2024-10-21

amitrole and Acute Lung Injury

amitrole has been researched along with Acute Lung Injury in 3 studies

Amitrole: A non-selective post-emergence, translocated herbicide. According to the Seventh Annual Report on Carcinogens (PB95-109781, 1994) this substance may reasonably be anticipated to be a carcinogen. (From Merck Index, 12th ed) It is an irreversible inhibitor of CATALASE, and thus impairs activity of peroxisomes.
amitrole : A member of the class of triazoles that is 1H-1,2,4-triazole substituted by an amino group at position 3. Used to control annual grasses and aquatic weeds (but not on food crops because it causes cancer in laboratory animals). Its use within the EU was banned from September 2017 on the grounds of potential groundwater contamination and risks to aquatic life; there have also been concerns about its endocrine-disrupting properties.

Acute Lung Injury: A condition of lung damage that is characterized by bilateral pulmonary infiltrates (PULMONARY EDEMA) rich in NEUTROPHILS, and in the absence of clinical HEART FAILURE. This can represent a spectrum of pulmonary lesions, endothelial and epithelial, due to numerous factors (physical, chemical, or biological).

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zmijewski, JW2
Lorne, E2
Zhao, X1
Tsuruta, Y1
Sha, Y2
Liu, G2
Abraham, E2
Banerjee, S1
Mu, J1
Xie, K1
Hou, L1
Peng, D1
Shang, L1
Ji, G1
Li, J1
Lu, Y1
Xiong, L1

Other Studies

3 other studies available for amitrole and Acute Lung Injury

ArticleYear
Antiinflammatory effects of hydrogen peroxide in neutrophil activation and acute lung injury.
    American journal of respiratory and critical care medicine, 2009, Apr-15, Volume: 179, Issue:8

    Topics: Acatalasia; Acute Lung Injury; Amitrole; Animals; Catalase; Disease Models, Animal; Enzyme Inhibitor

2009
Modulation of SCF beta-TrCP-dependent I kappaB alpha ubiquitination by hydrogen peroxide.
    The Journal of biological chemistry, 2010, Jan-22, Volume: 285, Issue:4

    Topics: Acatalasia; Acute Lung Injury; Amitrole; Animals; Catalase; Cells, Cultured; Enzyme Inhibitors; Huma

2010
Subanesthetic dose of isoflurane protects against zymosan-induced generalized inflammation and its associated acute lung injury in mice.
    Shock (Augusta, Ga.), 2010, Volume: 34, Issue:2

    Topics: Acute Lung Injury; Amitrole; Animals; Catalase; Inflammation; Isoflurane; Male; Mice; Multiple Organ

2010