amitrole has been researched along with Acidosis in 2 studies
Amitrole: A non-selective post-emergence, translocated herbicide. According to the Seventh Annual Report on Carcinogens (PB95-109781, 1994) this substance may reasonably be anticipated to be a carcinogen. (From Merck Index, 12th ed) It is an irreversible inhibitor of CATALASE, and thus impairs activity of peroxisomes.
amitrole : A member of the class of triazoles that is 1H-1,2,4-triazole substituted by an amino group at position 3. Used to control annual grasses and aquatic weeds (but not on food crops because it causes cancer in laboratory animals). Its use within the EU was banned from September 2017 on the grounds of potential groundwater contamination and risks to aquatic life; there have also been concerns about its endocrine-disrupting properties.
Acidosis: A pathologic condition of acid accumulation or depletion of base in the body. The two main types are RESPIRATORY ACIDOSIS and metabolic acidosis, due to metabolic acid build up.
| Excerpt | Relevance | Reference |
|---|---|---|
| "02; (2) 2 Na-dependent acid extruders and a Cl-dependent acid loading carrier exist and are functional; (3) alcohol functions in a concentration-dependent manner to reduce pHi and increase NHE activity, but it does not affect CHE activity; and (4) fomepizole, a specific alcohol dehydrogenase inhibitor, does not change the intracellular acidosis and NHE activity-induced by alcohol, whereas 3-amino-1, 2,4-trizole, a specific catalase inhibitor, entirely abolishes these effects." | 3.77 | Functional characterization of transmembrane intracellular pH regulators and mechanism of alcohol-induced intracellular acidosis in human umbilical cord blood stem cell-like cells. ( Chen, MH; Chen, WH; Lee, CY; Liu, JY; Loh, SH; Ou, CC; Tsai, CS; Tsai, YT, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tsai, YT | 1 |
| Liu, JY | 1 |
| Lee, CY | 1 |
| Tsai, CS | 1 |
| Chen, MH | 1 |
| Ou, CC | 1 |
| Chen, WH | 1 |
| Loh, SH | 1 |
| Jeganathan, PS | 1 |
| Namasivayam, A | 1 |
2 other studies available for amitrole and Acidosis
| Article | Year |
|---|---|
Functional characterization of transmembrane intracellular pH regulators and mechanism of alcohol-induced intracellular acidosis in human umbilical cord blood stem cell-like cells.
Topics: Acidosis; Amitrole; Antigens, CD34; Antiporters; Catalase; Cells, Cultured; Dose-Response Relationsh | 2011 |
Role of acidosis in the changes of rat brain monoamines after methanol administration & effect of blocking methanol metabolism by 4-methyl pyrazole & 3-amino-1,2,4-triazole.
Topics: Acidosis; Amitrole; Animals; Brain Chemistry; Catecholamines; Fomepizole; Methanol; Pyrazoles; Rats; | 1988 |