Page last updated: 2024-10-21

amitrole and Acatalasemia

amitrole has been researched along with Acatalasemia in 8 studies

Amitrole: A non-selective post-emergence, translocated herbicide. According to the Seventh Annual Report on Carcinogens (PB95-109781, 1994) this substance may reasonably be anticipated to be a carcinogen. (From Merck Index, 12th ed) It is an irreversible inhibitor of CATALASE, and thus impairs activity of peroxisomes.
amitrole : A member of the class of triazoles that is 1H-1,2,4-triazole substituted by an amino group at position 3. Used to control annual grasses and aquatic weeds (but not on food crops because it causes cancer in laboratory animals). Its use within the EU was banned from September 2017 on the grounds of potential groundwater contamination and risks to aquatic life; there have also been concerns about its endocrine-disrupting properties.

Research Excerpts

ExcerptRelevanceReference
"Methanol metabolism was also studied in acatalasemic and normal mice treated with 3-amino-1,2,4-triazole (AT), which is known to be an inhibitor of catalase (EC 1."1.28Methanol metabolism in acatalasemic mice. ( Karinje, KU; Ogata, M, 1990)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19903 (37.50)18.7374
1990's2 (25.00)18.2507
2000's1 (12.50)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zmijewski, JW3
Lorne, E2
Zhao, X1
Tsuruta, Y1
Sha, Y2
Liu, G2
Abraham, E3
Banerjee, S2
Bae, H1
Friggeri, A1
Lazarowski, ER1
Feinstein, RN1
Jones, GL1
Masters, CJ1
Ohmori, T1
Ogata, M2
Karinje, KU1
Meguro, T1

Other Studies

8 other studies available for amitrole and Acatalasemia

ArticleYear
Antiinflammatory effects of hydrogen peroxide in neutrophil activation and acute lung injury.
    American journal of respiratory and critical care medicine, 2009, Apr-15, Volume: 179, Issue:8

    Topics: Acatalasia; Acute Lung Injury; Amitrole; Animals; Catalase; Disease Models, Animal; Enzyme Inhibitor

2009
Modulation of SCF beta-TrCP-dependent I kappaB alpha ubiquitination by hydrogen peroxide.
    The Journal of biological chemistry, 2010, Jan-22, Volume: 285, Issue:4

    Topics: Acatalasia; Acute Lung Injury; Amitrole; Animals; Catalase; Cells, Cultured; Enzyme Inhibitors; Huma

2010
Exposure to hydrogen peroxide induces oxidation and activation of AMP-activated protein kinase.
    The Journal of biological chemistry, 2010, Oct-22, Volume: 285, Issue:43

    Topics: Acatalasia; Adenosine Monophosphate; Adenosine Triphosphate; Amitrole; AMP-Activated Protein Kinases

2010
Cinnabarinate synthase activity in normal and acatalasemic mice.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1978, Volume: 158, Issue:3

    Topics: 3-Hydroxyanthranilic Acid; Acatalasia; Amitrole; Animals; Catalase; Copper; Liver; Manganese; Mice;

1978
On the turnover and proteolysis of catalase in tissues of the guinea pig and acatalasemic mice.
    Archives of biochemistry and biophysics, 1976, Volume: 173, Issue:2

    Topics: Acatalasia; Amitrole; Animals; Catalase; Chymotrypsin; Female; Guinea Pigs; Half-Life; Kidney; Kinet

1976
Methemoglobin formation by potassium ferrocyanide in the hemolysate of acatalasemic mice.
    Acta medica Okayama, 1991, Volume: 45, Issue:4

    Topics: Acatalasia; Amitrole; Animals; Catalase; Ferrocyanides; Hemolysis; Male; Methemoglobin; Mice; Mice,

1991
Methanol metabolism in acatalasemic mice.
    Physiological chemistry and physics and medical NMR, 1990, Volume: 22, Issue:4

    Topics: Acatalasia; Amitrole; Animals; Carbon Dioxide; Ethanol; Formates; Male; Methanol; Mice; Mice, Inbred

1990
Effect of aminotriazole on mercury uptake by the fetus of normal and acatalasemic mice exposed to metallic mercury.
    Acta medica Okayama, 1987, Volume: 41, Issue:6

    Topics: Acatalasia; Amitrole; Animals; Female; Fetus; Liver; Maternal-Fetal Exchange; Mercury; Mice; Mice, I

1987