amitriptyline has been researched along with Venous Thromboembolism in 2 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Venous Thromboembolism: Obstruction of a vein or VEINS (embolism) by a blood clot (THROMBUS) in the blood stream.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Current exposure to amitriptyline, particularly at high doses, was associated with an increased risk of idiopathic venous thromboembolism." | 3.74 | Antidepressant drug use and risk of venous thromboembolism. ( Jick, SS; Li, L, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Morris, MC | 1 |
| Kassam, F | 1 |
| Bercz, A | 1 |
| Beckmann, N | 1 |
| Schumacher, F | 1 |
| Gulbins, E | 1 |
| Makley, AT | 1 |
| Goodman, MD | 1 |
| Jick, SS | 1 |
| Li, L | 1 |
2 other studies available for amitriptyline and Venous Thromboembolism
| Article | Year |
|---|---|
The Role of Chemoprophylactic Agents in Modulating Platelet Aggregability After Traumatic Brain Injury.
Topics: Amitriptyline; Animals; Aspirin; Blood Coagulation; Brain Injuries, Traumatic; Disease Models, Anima | 2019 |
Antidepressant drug use and risk of venous thromboembolism.
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents; Case-Control Studies; Dose-Response Relationship, | 2008 |