amitriptyline has been researched along with Tinnitus in 15 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Tinnitus: A nonspecific symptom of hearing disorder characterized by the sensation of buzzing, ringing, clicking, pulsations, and other noises in the ear. Objective tinnitus refers to noises generated from within the ear or adjacent structures that can be heard by other individuals. The term subjective tinnitus is used when the sound is audible only to the affected individual. Tinnitus may occur as a manifestation of COCHLEAR DISEASES; VESTIBULOCOCHLEAR NERVE DISEASES; INTRACRANIAL HYPERTENSION; CRANIOCEREBRAL TRAUMA; and other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated the effect of amitriptyline, a tricyclic antidepressant, on patients with subjective tinnitus." | 9.09 | Efficacy of amitriptyline in the treatment of subjective tinnitus. ( Bayar, N; Belgin, E; Böke, B; Turan, E, 2001) |
| "Analysis shows that cyclobenzaprine offers some benefit to patients with tinnitus on both tinnitus intensity and tinnitus distress, while a waiting list control group does not demonstrate any improvement: 24% of the tinnitus patients showed a clear response to cyclobenzaprine with a reduction of 53% on tinnitus intensity and 25% had a clear response to cyclobenzaprine with a reduction of 55% on tinnitus distress." | 7.78 | Treatment of tinnitus with cyclobenzaprine: an open-label study. ( De Ridder, D; Figueiredo, R; Vanneste, S, 2012) |
| "We report on a case of unilateral tinnitus after a short course of low-dose amitriptyline for neuralgic foot pain." | 7.74 | An unusual case of prolonged tinnitus following low-dose amitriptyline. ( Johnston, M; Mendis, D, 2008) |
| "The objective of this article is to discuss the clinically effective use of gabapentin in patients with tinnitus." | 7.71 | Gabapentin for the treatment of tinnitus: a case report. ( Zapp, JJ, 2001) |
| "Treatment with cyclobenzaprine alone had no effect on the ability of gaps to suppress the startle response." | 5.42 | Partial to complete suppression of unilateral noise-induced tinnitus in rats after cyclobenzaprine treatment. ( Blair, C; Le Prell, C; Lobarinas, E; Spankovich, C, 2015) |
| "We investigated the effect of amitriptyline, a tricyclic antidepressant, on patients with subjective tinnitus." | 5.09 | Efficacy of amitriptyline in the treatment of subjective tinnitus. ( Bayar, N; Belgin, E; Böke, B; Turan, E, 2001) |
| "Analysis shows that cyclobenzaprine offers some benefit to patients with tinnitus on both tinnitus intensity and tinnitus distress, while a waiting list control group does not demonstrate any improvement: 24% of the tinnitus patients showed a clear response to cyclobenzaprine with a reduction of 53% on tinnitus intensity and 25% had a clear response to cyclobenzaprine with a reduction of 55% on tinnitus distress." | 3.78 | Treatment of tinnitus with cyclobenzaprine: an open-label study. ( De Ridder, D; Figueiredo, R; Vanneste, S, 2012) |
| "We report on a case of unilateral tinnitus after a short course of low-dose amitriptyline for neuralgic foot pain." | 3.74 | An unusual case of prolonged tinnitus following low-dose amitriptyline. ( Johnston, M; Mendis, D, 2008) |
| "The objective of this article is to discuss the clinically effective use of gabapentin in patients with tinnitus." | 3.71 | Gabapentin for the treatment of tinnitus: a case report. ( Zapp, JJ, 2001) |
| "Antidepressant drugs have been used to treat tinnitus in patients with and without depressive symptoms." | 2.48 | Antidepressants for patients with tinnitus. ( Baldo, P; Cecco, S; Doree, C; McFerran, D; Molin, P, 2012) |
| "Treatment with cyclobenzaprine alone had no effect on the ability of gaps to suppress the startle response." | 1.42 | Partial to complete suppression of unilateral noise-induced tinnitus in rats after cyclobenzaprine treatment. ( Blair, C; Le Prell, C; Lobarinas, E; Spankovich, C, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (26.67) | 18.7374 |
| 1990's | 2 (13.33) | 18.2507 |
| 2000's | 4 (26.67) | 29.6817 |
| 2010's | 5 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lobarinas, E | 1 |
| Blair, C | 1 |
| Spankovich, C | 1 |
| Le Prell, C | 1 |
| Langguth, B | 2 |
| Landgrebe, M | 2 |
| Wittmann, M | 1 |
| Kleinjung, T | 1 |
| Hajak, G | 1 |
| Coelho, C | 1 |
| Figueiredo, R | 2 |
| Frank, E | 1 |
| Burger, J | 1 |
| Schecklmann, M | 1 |
| Elgoyhen, AB | 1 |
| Vanneste, S | 1 |
| De Ridder, D | 1 |
| Baldo, P | 1 |
| Doree, C | 1 |
| Molin, P | 1 |
| McFerran, D | 1 |
| Cecco, S | 1 |
| Curtin, F | 1 |
| Redmund, C | 1 |
| Mendis, D | 1 |
| Johnston, M | 1 |
| Shea, JJ | 1 |
| Miles, SW | 1 |
| Fleischhauer, J | 1 |
| Zapp, JJ | 1 |
| Bayar, N | 1 |
| Böke, B | 1 |
| Turan, E | 1 |
| Belgin, E | 1 |
| Koshes, RJ | 1 |
| Feder, R | 1 |
| Takao, T | 1 |
2 reviews available for amitriptyline and Tinnitus
| Article | Year |
|---|---|
Antidepressants for patients with tinnitus.
Topics: Amitriptyline; Antidepressive Agents; Depression; Humans; Nortriptyline; Paroxetine; Randomized Cont | 2012 |
Medical treatment of tinnitus.
Topics: Amitriptyline; Anti-Arrhythmia Agents; Auditory Pathways; Drug Combinations; Humans; Lidocaine; Pain | 1984 |
2 trials available for amitriptyline and Tinnitus
| Article | Year |
|---|---|
Reduction of tinnitus severity by the centrally acting muscle relaxant cyclobenzaprine: an open-label pilot study.
Topics: Adult; Aged; Amitriptyline; Clonidine; Female; Humans; Male; Middle Aged; Muscle Relaxants, Central; | 2012 |
Efficacy of amitriptyline in the treatment of subjective tinnitus.
Topics: Adolescent; Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Female; Follow-Up Studies; Human | 2001 |
11 other studies available for amitriptyline and Tinnitus
| Article | Year |
|---|---|
Partial to complete suppression of unilateral noise-induced tinnitus in rats after cyclobenzaprine treatment.
Topics: Amitriptyline; Animals; Male; Noise; Rats; Rats, Sprague-Dawley; Reflex, Startle; Tinnitus | 2015 |
Persistent tinnitus induced by tricyclic antidepressants.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Cognitive Behavioral Therapy; Depressive Dis | 2010 |
Treatment of tinnitus with cyclobenzaprine: an open-label study.
Topics: Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Female; Humans; Male; Middle Aged; Mus | 2012 |
Musical hallucinations during a treatment with benzodiazepine.
Topics: Amitriptyline; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Depressive Disorder; Dose-Re | 2002 |
An unusual case of prolonged tinnitus following low-dose amitriptyline.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Dose-Response Relationship, Drug; Female; Fo | 2008 |
Amitriptyline side effect.
Topics: Akathisia, Drug-Induced; Amitriptyline; Female; Humans; Middle Aged; Tinnitus | 1980 |
Acute hypacusis of the inner ear as a result of reduced blood pressure by amitriptyline. A rare complication of the therapy with amitriptyline.
Topics: Adult; Amitriptyline; Auditory Threshold; Blood Pressure; Cochlea; Depressive Disorder; Ear, Inner; | 1982 |
Gabapentin for the treatment of tinnitus: a case report.
Topics: Acetates; Amines; Amitriptyline; Analgesics; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; | 2001 |
Use of amitriptyline in a patient with tinnitus.
Topics: Aged; Amitriptyline; Depressive Disorder; Female; Humans; Psychotherapy; Tinnitus | 1992 |
Tinnitus associated with amitriptyline.
Topics: Adult; Amitriptyline; Depressive Disorder; Humans; Male; Tinnitus | 1990 |
[Use of Tryptanol in otorhinolaryngologic diseases].
Topics: Administration, Oral; Adult; Aged; Amitriptyline; Female; Hearing Disorders; Hearing Tests; Humans; | 1971 |