amitriptyline has been researched along with Teratogenesis in 1 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Teratogenesis: The formation of CONGENITAL ABNORMALITIES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Amitriptyline is a tricyclic antidepressant commonly prescribed in humans for pain and sleep disorders and in non-human primates for self-injurious behaviors." | 1.62 | Fetal teratogenicity in a rhesus macaque (Macaca mulatta): Association with the chronic maternal treatment of amitriptyline. ( Bonenberger, D; Chan, AWS; Hamlet, T; Hunter, CE; Li, C; Stammen, RL; Stroud, FC; Zhang, X, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hunter, CE | 1 |
| Stammen, RL | 1 |
| Hamlet, T | 1 |
| Bonenberger, D | 1 |
| Li, C | 1 |
| Zhang, X | 1 |
| Stroud, FC | 1 |
| Chan, AWS | 1 |
1 other study available for amitriptyline and Teratogenesis
| Article | Year |
|---|---|
Fetal teratogenicity in a rhesus macaque (Macaca mulatta): Association with the chronic maternal treatment of amitriptyline.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Female; Macaca mulatta; Maternal Exposure; | 2021 |