Page last updated: 2024-10-22

amitriptyline and Tension-Type Headache

amitriptyline has been researched along with Tension-Type Headache in 39 studies

Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.

Tension-Type Headache: A common primary headache disorder, characterized by a dull, non-pulsatile, diffuse, band-like (or vice-like) PAIN of mild to moderate intensity in the HEAD; SCALP; or NECK. The subtypes are classified by frequency and severity of symptoms. There is no clear cause even though it has been associated with MUSCLE CONTRACTION and stress. (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)

Research Excerpts

ExcerptRelevanceReference
"The tricyclic antidepressant amitriptyline is the only documented and most widely used prophylactic drug for chronic tension-type headache (CTTH)."9.11Analgesic effect of amitriptyline in chronic tension-type headache is not directly related to serotonin reuptake inhibition. ( Ashina, S; Bendtsen, L; Jensen, R, 2004)
"In the present study, we examined clinical and laser-evoked potentials (LEP) features in two groups of chronic tension-type headache (CTTH) patients treated with two different approaches: intra-oral appliance of prosthesis, aiming to reduce muscular tenderness, and 10 mg daily amitriptyline."9.11Effects of amitriptyline and intra-oral device appliance on clinical and laser-evoked potentials features in chronic tension-type headache. ( Barile, G; de Tommaso, M; Di Venere, D; Genco, S; Guido, M; Lamberti, P; Libro, G; Livrea, P; Monetti, C; Serpino, C; Shevel, E, 2005)
"To evaluate the clinical efficacy of paroxetine hydrochloride for chronic tension-type headache not responding to amitriptyline hydrochloride."9.10Treating chronic tension-type headache not responding to amitriptyline hydrochloride with paroxetine hydrochloride: a pilot evaluation. ( Cordingley, GE; Holroyd, KA; Labus, JS; O'Donnell, FJ, 2003)
"The tricyclic anti-depressant amitriptyline is widely used in the treatment of chronic tension-type headache."9.09Amitriptyline reduces myofascial tenderness in patients with chronic tension-type headache. ( Bendtsen, L; Jensen, R, 2000)
"Although the tricyclic antidepressant amitriptyline is extensively used in the prophylactic treatment of chronic tension-type headache, only few studies have investigated the efficacy of this treatment and the results are contradictory."9.08A non-selective (amitriptyline), but not a selective (citalopram), serotonin reuptake inhibitor is effective in the prophylactic treatment of chronic tension-type headache. ( Bendtsen, L; Jensen, R; Olesen, J, 1996)
"In a double-blind, placebo-controlled trial, the effect of 75 mg of a slow-release formulation of amitriptyline on the clinical severity of chronic tension-type headache and on headache-associated neurophysiological parameters (EMG activity, exteroceptive suppression of temporal muscle activity, contingent negative variation (CNV) and experimental pain sensitivity) was investigated."9.07Chronic tension-type headache: amitriptyline reduces clinical headache-duration and experimental pain sensitivity but does not alter pericranial muscle activity readings. ( Göbel, H; Hamouz, V; Hansen, C; Heininger, K; Heuss, D; Hirsch, S; Lindner, V; Soyka, D, 1994)
"The objective of this study was to investigate differences in clinical, psychological, and psychophysical outcomes according to use of prophylactic medication (amitriptyline) in tension-type headache (TTH)."7.91Variables Associated With the Use of Prophylactic Amitriptyline Treatment in Patients With Tension-type Headache. ( Arendt-Nielsen, L; Castaldo, M; Fernández-de-Las-Peñas, C; Ordás-Bandera, C; Palacios-Ceña, M; Torelli, P; Wang, K, 2019)
"Patients presenting to the headache clinic with a diagnosis of tension-type headache that justified prophylactic therapy (frequent episodic tension-type headache or chronic tension-type headache) were given the choice of amitriptyline (AMT) treatment or hypnotic relaxation (HR), and were treated accordingly."7.78Hypnotic relaxation vs amitriptyline for tension-type headache: let the patient choose. ( Adahan, HM; Ben-Hur, T; Ezra, Y; Goldman, S; Gotkine, M, 2012)
"The tricyclic antidepressant, amitriptyline, is an effective drug for the treatment of chronic tension-type headache and for other chronic pain syndromes, but it is also effective in the prophylaxis of an episodic type of headache such as migraine."7.70Amitriptyline is effective in chronic but not in episodic tension-type headache: pathogenetic implications. ( Barbanti, P; Catarci, T; Cerbo, R; Fabbrini, G; Pascali, MP, 1998)
"Daily pain scores using a facial pain diary were recorded over eight weeks."6.78A Randomized Controlled Trial comparing the efficacy of low-dose amitriptyline, amitriptyline with pindolol and surrogate placebo in the treatment of chronic tension-type facial pain. ( Agius, AM; Jones, NS; Muscat, R, 2013)
"Patients often present with chronic facial pain despite normal nasal endoscopy and sinus computerized tomography."6.78Serial blood serotonin levels in a randomized controlled trial comparing the efficacy of low-dose amitriptyline, amitriptyline with pindolol and surrogate placebo in patients with chronic tension-type facial pain. ( Agius, AM; Jones, NS; Muscat, R, 2013)
"Amitriptyline is a tricyclic antidepressant, considered the treatment of choice for different types of chronic pain, including chronic myofascial pain."6.44Use of amitriptyline for the treatment of chronic tension-type headache. Review of the literature. ( Gay Escoda, C; Torrente Castells, E; Vázquez Delgado, E, 2008)
"Headache is one of the most frequently reported symptoms in post-COVID patients."5.72Amitriptyline for post-COVID headache: effectiveness, tolerability, and response predictors. ( Arias-Rivas, S; Gago-Veiga, AB; García-Azorín, D; Gonzalez-Martinez, A; Guerrero-Peral, ÁL; Sierra, Á; Silva, L, 2022)
" In this study relaxation training, administered in a limited contact format, and amitriptyline were compared for juvenile episodic tension-type headache."5.12Pharmacological treatment compared to behavioural treatment for juvenile tension-type headache: results at two-year follow-up. ( Andrasik, F; Bussone, G; Grazzi, L; Usai, S, 2007)
"The tricyclic antidepressant amitriptyline is the only documented and most widely used prophylactic drug for chronic tension-type headache (CTTH)."5.11Analgesic effect of amitriptyline in chronic tension-type headache is not directly related to serotonin reuptake inhibition. ( Ashina, S; Bendtsen, L; Jensen, R, 2004)
"In the present study, we examined clinical and laser-evoked potentials (LEP) features in two groups of chronic tension-type headache (CTTH) patients treated with two different approaches: intra-oral appliance of prosthesis, aiming to reduce muscular tenderness, and 10 mg daily amitriptyline."5.11Effects of amitriptyline and intra-oral device appliance on clinical and laser-evoked potentials features in chronic tension-type headache. ( Barile, G; de Tommaso, M; Di Venere, D; Genco, S; Guido, M; Lamberti, P; Libro, G; Livrea, P; Monetti, C; Serpino, C; Shevel, E, 2005)
"To evaluate the clinical efficacy of paroxetine hydrochloride for chronic tension-type headache not responding to amitriptyline hydrochloride."5.10Treating chronic tension-type headache not responding to amitriptyline hydrochloride with paroxetine hydrochloride: a pilot evaluation. ( Cordingley, GE; Holroyd, KA; Labus, JS; O'Donnell, FJ, 2003)
"The tricyclic anti-depressant amitriptyline is widely used in the treatment of chronic tension-type headache."5.09Amitriptyline reduces myofascial tenderness in patients with chronic tension-type headache. ( Bendtsen, L; Jensen, R, 2000)
"Although the tricyclic antidepressant amitriptyline is extensively used in the prophylactic treatment of chronic tension-type headache, only few studies have investigated the efficacy of this treatment and the results are contradictory."5.08A non-selective (amitriptyline), but not a selective (citalopram), serotonin reuptake inhibitor is effective in the prophylactic treatment of chronic tension-type headache. ( Bendtsen, L; Jensen, R; Olesen, J, 1996)
"In a double-blind, placebo-controlled trial, the effect of 75 mg of a slow-release formulation of amitriptyline on the clinical severity of chronic tension-type headache and on headache-associated neurophysiological parameters (EMG activity, exteroceptive suppression of temporal muscle activity, contingent negative variation (CNV) and experimental pain sensitivity) was investigated."5.07Chronic tension-type headache: amitriptyline reduces clinical headache-duration and experimental pain sensitivity but does not alter pericranial muscle activity readings. ( Göbel, H; Hamouz, V; Hansen, C; Heininger, K; Heuss, D; Hirsch, S; Lindner, V; Soyka, D, 1994)
"The objective of this study was to investigate differences in clinical, psychological, and psychophysical outcomes according to use of prophylactic medication (amitriptyline) in tension-type headache (TTH)."3.91Variables Associated With the Use of Prophylactic Amitriptyline Treatment in Patients With Tension-type Headache. ( Arendt-Nielsen, L; Castaldo, M; Fernández-de-Las-Peñas, C; Ordás-Bandera, C; Palacios-Ceña, M; Torelli, P; Wang, K, 2019)
"Patients presenting to the headache clinic with a diagnosis of tension-type headache that justified prophylactic therapy (frequent episodic tension-type headache or chronic tension-type headache) were given the choice of amitriptyline (AMT) treatment or hypnotic relaxation (HR), and were treated accordingly."3.78Hypnotic relaxation vs amitriptyline for tension-type headache: let the patient choose. ( Adahan, HM; Ben-Hur, T; Ezra, Y; Goldman, S; Gotkine, M, 2012)
"Children aged 16 years or less with first diagnosed of either migraine or tension-type headache were reassured the cause of headache and treated by avoiding triggering factors, taking intermittent analgesics or a daily preventive medication such as propanolol 10 mg two times a day or amitriptyline 10 mg at night for patients who were suffered from the frequent headache attacks whether had to stop activity or go to sleep."3.74Short-term outcomes of tension type and migraine headache in children. ( Ruangsuwan, S; Sri-udomkajorn, S, 2008)
"The tricyclic antidepressant, amitriptyline, is an effective drug for the treatment of chronic tension-type headache and for other chronic pain syndromes, but it is also effective in the prophylaxis of an episodic type of headache such as migraine."3.70Amitriptyline is effective in chronic but not in episodic tension-type headache: pathogenetic implications. ( Barbanti, P; Catarci, T; Cerbo, R; Fabbrini, G; Pascali, MP, 1998)
"Daily pain scores using a facial pain diary were recorded over eight weeks."2.78A Randomized Controlled Trial comparing the efficacy of low-dose amitriptyline, amitriptyline with pindolol and surrogate placebo in the treatment of chronic tension-type facial pain. ( Agius, AM; Jones, NS; Muscat, R, 2013)
"Patients often present with chronic facial pain despite normal nasal endoscopy and sinus computerized tomography."2.78Serial blood serotonin levels in a randomized controlled trial comparing the efficacy of low-dose amitriptyline, amitriptyline with pindolol and surrogate placebo in patients with chronic tension-type facial pain. ( Agius, AM; Jones, NS; Muscat, R, 2013)
"The treatment of headache is usually successful and thus highly rewarding for physicians of all medical specialties."2.58Hints on Diagnosing and Treating Headache. ( May, A, 2018)
"Amitriptyline is a tricyclic antidepressant, considered the treatment of choice for different types of chronic pain, including chronic myofascial pain."2.44Use of amitriptyline for the treatment of chronic tension-type headache. Review of the literature. ( Gay Escoda, C; Torrente Castells, E; Vázquez Delgado, E, 2008)
"Drug prevention of migraine is recommended if more than three attacks occur per month, acute drug treatment is insufficient, or very severe attacks with aura are the main problem."2.44[Alternatives to beta blockers in preventive migraine treatment]. ( Evers, S, 2008)
"In over 40% of migraineurs the condition begins before 18 years of age."2.42Primary headaches in children and adolescents. ( Grazzi, L, 2004)
"Headache is one of the most frequently reported symptoms in post-COVID patients."1.72Amitriptyline for post-COVID headache: effectiveness, tolerability, and response predictors. ( Arias-Rivas, S; Gago-Veiga, AB; García-Azorín, D; Gonzalez-Martinez, A; Guerrero-Peral, ÁL; Sierra, Á; Silva, L, 2022)
"The surgical treatment of migraine headache is a recent innovation that has broadened the potential patient population who may benefit from craniofacial surgical techniques to millions of affected adults."1.35Review of pediatric migraine headaches refractory to medical management. ( Eshraghi, Y; Gosain, AK; Kung, TA; Scher, MS; Totonchi, A, 2009)
"Chronic tension headache sufferers received structured massage therapy treatment directed toward neck and shoulder muscles."1.31Massage therapy and frequency of chronic tension headaches. ( Chandler, C; Moraska, A; Quinn, C, 2002)

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.56)18.7374
1990's5 (12.82)18.2507
2000's23 (58.97)29.6817
2010's9 (23.08)24.3611
2020's1 (2.56)2.80

Authors

AuthorsStudies
Gonzalez-Martinez, A1
Guerrero-Peral, ÁL1
Arias-Rivas, S1
Silva, L1
Sierra, Á1
Gago-Veiga, AB1
García-Azorín, D1
May, A1
Scripter, C1
Palacios-Ceña, M1
Wang, K1
Castaldo, M1
Ordás-Bandera, C1
Torelli, P1
Arendt-Nielsen, L1
Fernández-de-Las-Peñas, C1
Ertsey, C1
Magyar, M1
Gyüre, T1
Balogh, E1
Bozsik, G1
Agius, AM2
Jones, NS2
Muscat, R2
Thapa, AS1
Torrente Castells, E1
Vázquez Delgado, E1
Gay Escoda, C1
Evers, S1
Kung, TA1
Totonchi, A1
Eshraghi, Y1
Scher, MS1
Gosain, AK1
Sri-udomkajorn, S1
Ruangsuwan, S1
Vernon, H1
Jansz, G1
Goldsmith, CH1
McDermaid, C1
Bezov, D1
Ashina, S2
Jensen, R4
Bendtsen, L4
Krishnan, A1
Silver, N3
Ezra, Y1
Gotkine, M1
Goldman, S1
Adahan, HM1
Ben-Hur, T1
Goadsby, P1
Quinn, C1
Chandler, C1
Moraska, A1
LANCE, JW1
CURRAN, DA1
Holroyd, KA2
Labus, JS1
O'Donnell, FJ2
Cordingley, GE2
Goadsby, PJ2
Rampello, L1
Alvano, A1
Chiechio, S1
Malaguarnera, M1
Raffaele, R1
Vecchio, I1
Nicoletti, F1
Grazzi, L2
de Tommaso, M1
Shevel, E1
Libro, G1
Guido, M1
Di Venere, D1
Genco, S1
Monetti, C1
Serpino, C1
Barile, G1
Lamberti, P1
Livrea, P1
Maggioni, F1
Ruffatti, S1
Dainese, F1
Mainardi, F1
Zanchin, G1
Peres, MF1
Vieira, DS1
Andrasik, F1
Usai, S1
Bussone, G1
Keays, AC1
Neher, JO1
Safranek, S1
Webb, CW1
Göbel, H1
Hamouz, V1
Hansen, C1
Heininger, K1
Hirsch, S1
Lindner, V1
Heuss, D1
Soyka, D1
Olesen, J1
Hobson, WH1
Shiraki, R1
Steiner, D1
Van Horn, M1
Cerbo, R1
Barbanti, P1
Fabbrini, G1
Pascali, MP1
Catarci, T1
Oguzhanoglu, A1
Sahiner, T1
Kurt, T1
Akalin, O1
Stensland, M1
Lipchik, GL1
Carlson, BW1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of the Impact of the HL Natural, Inc. Tension Relief Product on the Reduction of Symptoms in Adults Who Suffer From Mild to Moderate Tension Headaches[NCT04091555]117 participants (Actual)Interventional2019-10-16Completed
A Randomized Clinical Trial of Chiropractic Care for Headaches With and Without an Acupressure Device[NCT01509326]Phase 2/Phase 336 participants (Anticipated)Interventional2012-01-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

13 reviews available for amitriptyline and Tension-Type Headache

ArticleYear
Hints on Diagnosing and Treating Headache.
    Deutsches Arzteblatt international, 2018, 04-27, Volume: 115, Issue:17

    Topics: Amitriptyline; Analgesics, Non-Narcotic; Antihypertensive Agents; Headache; Humans; Metoprolol; Migr

2018
Headache: Tension-Type Headache.
    FP essentials, 2018, Volume: 473

    Topics: Amitriptyline; Analgesics, Non-Narcotic; Biofeedback, Psychology; Cognitive Behavioral Therapy; Diag

2018
[Tension type headache and its treatment possibilities].
    Ideggyogyaszati szemle, 2019, 01-30, Volume: 72, Issue:1-2

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Humans; Tension-Type Headache

2019
Use of amitriptyline for the treatment of chronic tension-type headache. Review of the literature.
    Medicina oral, patologia oral y cirugia bucal, 2008, Sep-01, Volume: 13, Issue:9

    Topics: Amitriptyline; Analgesics, Non-Narcotic; Chronic Disease; Humans; Tension-Type Headache

2008
[Alternatives to beta blockers in preventive migraine treatment].
    Der Nervenarzt, 2008, Volume: 79, Issue:10

    Topics: Adrenergic beta-Antagonists; Adult; Amitriptyline; Anticonvulsants; Botulinum Toxins, Type A; Calciu

2008
Pain perception studies in tension-type headache.
    Headache, 2011, Volume: 51, Issue:2

    Topics: Amitriptyline; Electric Stimulation Therapy; Humans; Muscle, Skeletal; Nitric Oxide Synthase; Pain P

2011
Headache (chronic tension-type).
    BMJ clinical evidence, 2009, Jul-22, Volume: 2009

    Topics: Amitriptyline; Headache; Humans; Manipulation, Osteopathic; Selective Serotonin Reuptake Inhibitors;

2009
Chronic tension-type headache.
    Clinical evidence, 2002, Issue:7

    Topics: Amitriptyline; Chronic Disease; Humans; Randomized Controlled Trials as Topic; Tension-Type Headache

2002
Headache (chronic tension type).
    Clinical evidence, 2003, Issue:9

    Topics: Acupuncture Therapy; Amitriptyline; Antidepressive Agents, Tricyclic; Cognitive Behavioral Therapy;

2003
Primary headaches in children and adolescents.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2004, Volume: 25 Suppl 3

    Topics: Adolescent; Amitriptyline; Antidepressive Agents, Tricyclic; Child; Headache Disorders; Humans; Migr

2004
Headache (chronic tension-type).
    Clinical evidence, 2003, Issue:10

    Topics: Acupuncture Therapy; Amitriptyline; Antidepressive Agents, Tricyclic; Cognitive Behavioral Therapy;

2003
Headache (chronic tension-type).
    Clinical evidence, 2005, Issue:14

    Topics: Acupuncture Therapy; Amitriptyline; Antidepressive Agents, Tricyclic; Cognitive Behavioral Therapy;

2005
Headache (chronic tension-type).
    American family physician, 2007, Jul-01, Volume: 76, Issue:1

    Topics: Amitriptyline; Analgesics, Non-Narcotic; Antidepressive Agents; Biofeedback, Psychology; Chronic Dis

2007

Trials

16 trials available for amitriptyline and Tension-Type Headache

ArticleYear
A Randomized Controlled Trial comparing the efficacy of low-dose amitriptyline, amitriptyline with pindolol and surrogate placebo in the treatment of chronic tension-type facial pain.
    Rhinology, 2013, Volume: 51, Issue:2

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Amitriptyline; Analysis of Variance; Antidepre

2013
Serial blood serotonin levels in a randomized controlled trial comparing the efficacy of low-dose amitriptyline, amitriptyline with pindolol and surrogate placebo in patients with chronic tension-type facial pain.
    Rhinology, 2013, Volume: 51, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Amitriptyline; Analysis of Variance; Antidepressive Agents, Tric

2013
Amitriptyline versus tizanidine in the management of tension-type headache in Nepal.
    Emergency medicine Australasia : EMA, 2013, Volume: 25, Issue:6

    Topics: Adolescent; Adrenergic Uptake Inhibitors; Adult; Aged; Amitriptyline; Analgesics; Clonidine; Female;

2013
A randomized, placebo-controlled clinical trial of chiropractic and medical prophylactic treatment of adults with tension-type headache: results from a stopped trial.
    Journal of manipulative and physiological therapeutics, 2009, Volume: 32, Issue:5

    Topics: Adult; Amitriptyline; Analgesics, Non-Narcotic; Chiropractic; Combined Modality Therapy; Factor Anal

2009
Treating chronic tension-type headache not responding to amitriptyline hydrochloride with paroxetine hydrochloride: a pilot evaluation.
    Headache, 2003, Volume: 43, Issue:9

    Topics: Adult; Amitriptyline; Analgesics; Antidepressive Agents, Tricyclic; Chronic Disease; Double-Blind Me

2003
Analgesic effect of amitriptyline in chronic tension-type headache is not directly related to serotonin reuptake inhibition.
    Pain, 2004, Volume: 108, Issue:1-2

    Topics: Adolescent; Adult; Amitriptyline; Analgesics, Non-Narcotic; Blood Platelets; Chronic Disease; Citalo

2004
Evaluation of the prophylactic efficacy of amitriptyline and citalopram, alone or in combination, in patients with comorbidity of depression, migraine, and tension-type headache.
    Neuropsychobiology, 2004, Volume: 50, Issue:4

    Topics: Adult; Amitriptyline; Analysis of Variance; Antidepressive Agents; Citalopram; Comorbidity; Depressi

2004
Effects of amitriptyline and intra-oral device appliance on clinical and laser-evoked potentials features in chronic tension-type headache.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2005, Volume: 26 Suppl 2

    Topics: Administration, Oral; Amitriptyline; Analysis of Variance; Antidepressive Agents, Tricyclic; Evaluat

2005
Weight variations in the prophylactic therapy of primary headaches: 6-month follow-up.
    The journal of headache and pain, 2005, Volume: 6, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Amines; Amitriptyline; Analgesics, Non-Narcotic; Anticonvulsants

2005
Pharmacological treatment compared to behavioural treatment for juvenile tension-type headache: results at two-year follow-up.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2007, Volume: 28 Suppl 2

    Topics: Adolescent; Age Factors; Aging; Amitriptyline; Analgesics, Non-Narcotic; Child; Disability Evaluatio

2007
Chronic tension-type headache: amitriptyline reduces clinical headache-duration and experimental pain sensitivity but does not alter pericranial muscle activity readings.
    Pain, 1994, Volume: 59, Issue:2

    Topics: Adult; Amitriptyline; Chronic Disease; Contingent Negative Variation; Double-Blind Method; Electroen

1994
A non-selective (amitriptyline), but not a selective (citalopram), serotonin reuptake inhibitor is effective in the prophylactic treatment of chronic tension-type headache.
    Journal of neurology, neurosurgery, and psychiatry, 1996, Volume: 61, Issue:3

    Topics: Adolescent; Adult; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Chronic Disease; Citalo

1996
Spinal manipulation vs. amitriptyline for the treatment of chronic tension headache: a randomized clinical trial.
    Journal of manipulative and physiological therapeutics, 1996, Volume: 19, Issue:4

    Topics: Adrenergic Uptake Inhibitors; Amitriptyline; Chronic Disease; Humans; Manipulation, Orthopedic; Pain

1996
Use of amitriptyline and fluoxetine in prophylaxis of migraine and tension-type headaches.
    Cephalalgia : an international journal of headache, 1999, Volume: 19, Issue:5

    Topics: Adult; Amitriptyline; Antidepressive Agents; Dose-Response Relationship, Drug; Drug Administration S

1999
Amitriptyline reduces myofascial tenderness in patients with chronic tension-type headache.
    Cephalalgia : an international journal of headache, 2000, Volume: 20, Issue:6

    Topics: Adult; Amitriptyline; Analgesics; Citalopram; Double-Blind Method; Electric Stimulation; Female; Hea

2000
Management of chronic tension-type headache with tricyclic antidepressant medication, stress management therapy, and their combination: a randomized controlled trial.
    JAMA, 2001, May-02, Volume: 285, Issue:17

    Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Behavior Therapy; Chronic Disease; Cognitive

2001

Other Studies

10 other studies available for amitriptyline and Tension-Type Headache

ArticleYear
Amitriptyline for post-COVID headache: effectiveness, tolerability, and response predictors.
    Journal of neurology, 2022, Volume: 269, Issue:11

    Topics: Amitriptyline; COVID-19; Female; Headache; Humans; Male; Migraine Disorders; Nausea; Retrospective S

2022
Variables Associated With the Use of Prophylactic Amitriptyline Treatment in Patients With Tension-type Headache.
    The Clinical journal of pain, 2019, Volume: 35, Issue:4

    Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Anxiety; Cost of Illness; Depression; Disabi

2019
Review of pediatric migraine headaches refractory to medical management.
    The Journal of craniofacial surgery, 2009, Volume: 20, Issue:1

    Topics: Adolescent; Amitriptyline; Analgesics, Non-Narcotic; Biofeedback, Psychology; Child; Female; Follow-

2009
Short-term outcomes of tension type and migraine headache in children.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2008, Volume: 91 Suppl 3

    Topics: Adolescent; Amitriptyline; Analgesics, Non-Narcotic; Child; Child, Preschool; Female; Humans; Male;

2008
Hypnotic relaxation vs amitriptyline for tension-type headache: let the patient choose.
    Headache, 2012, Volume: 52, Issue:5

    Topics: Adult; Amitriptyline; Analgesics, Non-Narcotic; Choice Behavior; Female; Follow-Up Studies; Humans;

2012
Massage therapy and frequency of chronic tension headaches.
    American journal of public health, 2002, Volume: 92, Issue:10

    Topics: Amitriptyline; Chronic Disease; Clinical Trials as Topic; Humans; Incidence; Massage; Pain Measureme

2002
TREATMENT OF CHRONIC TENSION HEADACHE.
    Lancet (London, England), 1964, Jun-06, Volume: 1, Issue:7345

    Topics: Amitriptyline; Amobarbital; Anxiety; Anxiety Disorders; Biomedical Research; Chlordiazepoxide; Diaze

1964
Tension-type headache with aura.
    Cephalalgia : an international journal of headache, 2006, Volume: 26, Issue:3

    Topics: Adrenergic Uptake Inhibitors; Amitriptyline; Anti-Anxiety Agents; Anticonvulsants; Anxiety; Bromazep

2006
Clinical inquiries. Is osteopathic manipulation effective for headaches?
    The Journal of family practice, 2008, Volume: 57, Issue:3

    Topics: Amitriptyline; Analgesics, Non-Narcotic; Headache; Humans; Manipulation, Osteopathic; Migraine Disor

2008
Amitriptyline is effective in chronic but not in episodic tension-type headache: pathogenetic implications.
    Headache, 1998, Volume: 38, Issue:6

    Topics: Adrenergic Uptake Inhibitors; Amitriptyline; Analgesics; Chronic Disease; Humans; Recurrence; Tensio

1998