amitriptyline has been researched along with Temporomandibular Joint Disorders in 3 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Temporomandibular Joint Disorders: A variety of conditions affecting the anatomic and functional characteristics of the temporomandibular joint. Factors contributing to the complexity of temporomandibular diseases are its relation to dentition and mastication and the symptomatic effects in other areas which account for referred pain to the joint and the difficulties in applying traditional diagnostic procedures to temporomandibular joint pathology where tissue is rarely obtained and x-rays are often inadequate or nonspecific. Common diseases are developmental abnormalities, trauma, subluxation, luxation, arthritis, and neoplasia. (From Thoma's Oral Pathology, 6th ed, pp577-600)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this pilot study was to evaluate the effectiveness of cognitive-behavioral therapy (CBT) and use of amitriptyline, a tricyclic antidepressant, in patients with chronic temporomandibular disorders (TMD)." | 7.77 | Effectiveness of cognitive-behavioral therapy and amitriptyline in patients with chronic temporomandibular disorders: a pilot study. ( Calderon, Pdos S; Camargo, AP; Conti, PC; Oliveira, LC; Ramos Netto, Tde C; Tabaquim, Mde L, 2011) |
| "Amitriptyline proved to be an efficient alternative treatment for chronic pain in TMD patients." | 6.71 | Clinical evaluation of amitriptyline for the control of chronic pain caused by temporomandibular joint disorders. ( Ambrosano, GM; de Andrade, ED; de Barbosa, JR; Nogueira, MT; Rizzatti-Barbosa, CM, 2003) |
| "Depression was assessed by the Beck Depression Inventory (BDI) short form." | 6.69 | Amitriptyline treatment of chronic pain in patients with temporomandibular disorders. ( Curtis, D; Levine, J; McCall, WD; Plesh, O, 2000) |
| "The aim of this pilot study was to evaluate the effectiveness of cognitive-behavioral therapy (CBT) and use of amitriptyline, a tricyclic antidepressant, in patients with chronic temporomandibular disorders (TMD)." | 3.77 | Effectiveness of cognitive-behavioral therapy and amitriptyline in patients with chronic temporomandibular disorders: a pilot study. ( Calderon, Pdos S; Camargo, AP; Conti, PC; Oliveira, LC; Ramos Netto, Tde C; Tabaquim, Mde L, 2011) |
| "Amitriptyline proved to be an efficient alternative treatment for chronic pain in TMD patients." | 2.71 | Clinical evaluation of amitriptyline for the control of chronic pain caused by temporomandibular joint disorders. ( Ambrosano, GM; de Andrade, ED; de Barbosa, JR; Nogueira, MT; Rizzatti-Barbosa, CM, 2003) |
| "Depression was assessed by the Beck Depression Inventory (BDI) short form." | 2.69 | Amitriptyline treatment of chronic pain in patients with temporomandibular disorders. ( Curtis, D; Levine, J; McCall, WD; Plesh, O, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Calderon, Pdos S | 1 |
| Tabaquim, Mde L | 1 |
| Oliveira, LC | 1 |
| Camargo, AP | 1 |
| Ramos Netto, Tde C | 1 |
| Conti, PC | 1 |
| Rizzatti-Barbosa, CM | 1 |
| Nogueira, MT | 1 |
| de Andrade, ED | 1 |
| Ambrosano, GM | 1 |
| de Barbosa, JR | 1 |
| Plesh, O | 1 |
| Curtis, D | 1 |
| Levine, J | 1 |
| McCall, WD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Prospective, Cross Over Gabapentin vs Amitriptyline Study on Patients Suffering From Masticatory Muscle Pain[NCT02339662] | Phase 4 | 50 participants (Anticipated) | Interventional | 2015-02-28 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for amitriptyline and Temporomandibular Joint Disorders
| Article | Year |
|---|---|
Clinical evaluation of amitriptyline for the control of chronic pain caused by temporomandibular joint disorders.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chronic Disease; Double-Blind Method; Facial Pain; | 2003 |
Amitriptyline treatment of chronic pain in patients with temporomandibular disorders.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Chronic Disease; Depression; Facial Pain; Fe | 2000 |
1 other study available for amitriptyline and Temporomandibular Joint Disorders
| Article | Year |
|---|---|
Effectiveness of cognitive-behavioral therapy and amitriptyline in patients with chronic temporomandibular disorders: a pilot study.
Topics: Adolescent; Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Chronic Pain; Cognitive Behavior | 2011 |