amitriptyline has been researched along with Tachycardia, Ventricular in 21 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Tachycardia, Ventricular: An abnormally rapid ventricular rhythm usually in excess of 150 beats per minute. It is generated within the ventricle below the BUNDLE OF HIS, either as autonomic impulse formation or reentrant impulse conduction. Depending on the etiology, onset of ventricular tachycardia can be paroxysmal (sudden) or nonparoxysmal, its wide QRS complexes can be uniform or polymorphic, and the ventricular beating may be independent of the atrial beating (AV dissociation).
| Excerpt | Relevance | Reference |
|---|---|---|
| "However, ventricular tachycardia was detected which did not respond to lidocaine, bicarbonate and cardioversion treatment." | 5.31 | Efficacy of long duration resuscitation and magnesium sulphate treatment in amitriptyline poisoning. ( Citak, A; Karaböcüoğlu, M; Soysal, DD; Uçsel, R; Uzel, N, 2002) |
| "Our data suggest that amitriptyline-induced inhibition of I(Na) unmasks the Brugada ECG phenotype and facilitates development of an arrhythmogenic substrate only in the setting of a genetic predisposition by creating repolarization heterogeneities that give rise to phase 2 reentry and VT." | 3.78 | Ionic and cellular mechanisms underlying the development of acquired Brugada syndrome in patients treated with antidepressants. ( Antzelevitch, C; Barajas-Martínez, H; Di Diego, JM; Hu, D; Minoura, Y; Sicouri, S; Zygmunt, AC, 2012) |
| "In the present case, arrhythmia and circulatory shock responded neither to alkalization and elevated sodium levels after infusion of sodium bicarbonate, nor to any other established therapies." | 1.48 | [Successful lipid rescue therapy in a case of severe amitriptyline/quetiapine intoxication]. ( Fischer, B; Otte, S; Sayk, F, 2018) |
| "Recently, we managed ventricular tachycardia in a young female presented with an impaired consciousness 10 h after intentionally ingesting 2500 mg amitriptyline." | 1.46 | Amitriptyline-induced ventricular tachycardia: a case report. ( Chowdhury, AW; Islam, MS; Kabir, SR; Kawser, S; Sabah, KMN; Saha, BP, 2017) |
| "Amitriptyline has the potential to cause unusual serious complications, such as abdominal compartment syndrome, irreversible central nervous system disability and lethal arrhythmia." | 1.46 | Unusual complications from amitriptyline intoxication. ( Maruguchi, H; Nakao, A; Nakayama, S; Nishimura, T, 2017) |
| "Cyclobenzaprine has potential for sodium channel blockade and ventricular dysrhythmias although cardiac toxicity due to cyclobenzaprine alone is rare." | 1.42 | Cardiac sodium channel blockade after an intentional ingestion of lacosamide, cyclobenzaprine, and levetiracetam: Case report. ( Cao, D; Chua-Tuan, JL; Hoyte, CO; Iwanicki, JL, 2015) |
| "She was in comatose, had generalized tonic clonic seizure, ventricular tachycardia, and wide QRS complexes." | 1.35 | Treatment of severe amitriptyline intoxication with plasmapheresis. ( Akyüz, M; Aydemir, C; Cabuk, H; Eldes, N; Kolsal, E; Numanoglu, V; Piskin, E; Tekin, IO, 2009) |
| "Magnesium sulfate is a very effective treatment in intractable arrhythmias caused by high-dose amitriptyline intoxication." | 1.34 | Efficacy of magnesium sulfate for treatment of ventricular tachycardia in amitriptyline intoxication. ( Babaoglu, K; Barn, E; Gokalp, AS; Sarisoy, O; Tugay, S, 2007) |
| "However, ventricular tachycardia was detected which did not respond to lidocaine, bicarbonate and cardioversion treatment." | 1.31 | Efficacy of long duration resuscitation and magnesium sulphate treatment in amitriptyline poisoning. ( Citak, A; Karaböcüoğlu, M; Soysal, DD; Uçsel, R; Uzel, N, 2002) |
| "After the appearance of ventricular tachycardia, they were treated with magnesium sulfate (45 mg/kg + 15 mg/kg/min) or lidocaine (1 mg/kg + 0." | 1.29 | Effects of magnesium sulfate and lidocaine in the treatment of ventricular arrhythmias in experimental amitriptyline poisoning in the rat. ( Abrahamsson, J; Knudsen, K, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.76) | 18.7374 |
| 1990's | 4 (19.05) | 18.2507 |
| 2000's | 6 (28.57) | 29.6817 |
| 2010's | 7 (33.33) | 24.3611 |
| 2020's | 3 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Garrett, P | 1 |
| Klupfel, S | 1 |
| Ryan, K | 1 |
| Benz, P | 1 |
| Zosel, A | 1 |
| Farkas, A | 1 |
| Theobald, J | 1 |
| Yang, XY | 1 |
| Song, XT | 1 |
| Zhang, Y | 1 |
| Sabah, KMN | 1 |
| Chowdhury, AW | 1 |
| Islam, MS | 1 |
| Saha, BP | 1 |
| Kabir, SR | 1 |
| Kawser, S | 1 |
| Otte, S | 1 |
| Fischer, B | 1 |
| Sayk, F | 1 |
| Nishimura, T | 1 |
| Maruguchi, H | 1 |
| Nakao, A | 1 |
| Nakayama, S | 1 |
| Butt, K | 1 |
| Ambati, S | 1 |
| Chua-Tuan, JL | 1 |
| Cao, D | 1 |
| Iwanicki, JL | 1 |
| Hoyte, CO | 1 |
| Abeyaratne, DD | 1 |
| Liyanapathirana, C | 1 |
| Gamage, A | 1 |
| Karunarathne, P | 1 |
| Botheju, M | 1 |
| Indrakumar, J | 1 |
| Kolsal, E | 1 |
| Tekin, IO | 1 |
| Piskin, E | 1 |
| Aydemir, C | 1 |
| Akyüz, M | 1 |
| Cabuk, H | 1 |
| Eldes, N | 1 |
| Numanoglu, V | 1 |
| Minoura, Y | 1 |
| Di Diego, JM | 1 |
| Barajas-Martínez, H | 1 |
| Zygmunt, AC | 1 |
| Hu, D | 1 |
| Sicouri, S | 1 |
| Antzelevitch, C | 1 |
| Srinivasa, V | 1 |
| Gerner, P | 1 |
| Haderer, A | 1 |
| Abdi, S | 1 |
| Jarolim, P | 1 |
| Wang, GK | 1 |
| LISSAC, J | 1 |
| SAVIER, CH | 1 |
| DUREPAIRE, H | 1 |
| AUZEPY, P | 1 |
| BROCARD, H | 1 |
| Baysal, T | 1 |
| Oran, B | 1 |
| Doğan, M | 1 |
| Cimen, D | 1 |
| Elmas, S | 1 |
| Karaaslan, S | 1 |
| Sarisoy, O | 1 |
| Babaoglu, K | 1 |
| Tugay, S | 1 |
| Barn, E | 1 |
| Gokalp, AS | 1 |
| Algren, DA | 1 |
| Sutter, ME | 1 |
| Ansel, GM | 2 |
| Coyne, K | 1 |
| Arnold, S | 1 |
| Nelson, SD | 2 |
| Meimer, JP | 1 |
| Knudsen, K | 1 |
| Abrahamsson, J | 1 |
| Coumbe, A | 1 |
| Perez-Martinez, AL | 1 |
| Fegan, AW | 1 |
| Hill, IR | 1 |
| Citak, A | 1 |
| Soysal, DD | 1 |
| Uçsel, R | 1 |
| Karaböcüoğlu, M | 1 |
| Uzel, N | 1 |
21 other studies available for amitriptyline and Tachycardia, Ventricular
| Article | Year |
|---|---|
Esmolol for intractable ventricular arrhythmias in major amitriptyline toxicity.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Arrhythmias, Cardiac; Humans; Propanolamines; Tachy | 2022 |
QTc Prolongation in Poison Center Exposures to CredibleMeds List of Substances with "Known Risk of Torsades de Pointes".
Topics: Amitriptyline; Arrhythmias, Cardiac; Diphenhydramine; Electrocardiography; Flecainide; Humans; Long | 2022 |
Wide QRS Complex Tachycardia With a Dominant R-Wave in Lead aVR-Is It Ventricular Tachycardia?
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Diagnosis, Differential; Doxepin; Drug Overdose; El | 2020 |
Amitriptyline-induced ventricular tachycardia: a case report.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Female; Humans; Suicide, Attempted; Tachycar | 2017 |
[Successful lipid rescue therapy in a case of severe amitriptyline/quetiapine intoxication].
Topics: Adrenergic Uptake Inhibitors; Adult; Amitriptyline; Arrhythmias, Cardiac; Drug Overdose; Female; Hum | 2018 |
Unusual complications from amitriptyline intoxication.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Brain Damage, Chronic; Coma; Humans; Intestinal Obs | 2017 |
A Peculiar Wide Complex Tachycardia.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Cardiotoxicity; Drug Overdose; Electrocardiography; | 2019 |
Cardiac sodium channel blockade after an intentional ingestion of lacosamide, cyclobenzaprine, and levetiracetam: Case report.
Topics: Acetamides; Adolescent; Amitriptyline; Anticonvulsants; Drug Interactions; Drug Overdose; Electrocar | 2015 |
Survival after severe amitriptyline poisoning with prolonged ventricular tachycardia and cardiac arrest.
Topics: Adult; Amitriptyline; Electrocardiography; Female; Heart Arrest; Humans; Pulmonary Edema; Survival A | 2016 |
Treatment of severe amitriptyline intoxication with plasmapheresis.
Topics: Amitriptyline; Child, Preschool; Coma; Drug Overdose; Female; Humans; Plasmapheresis; Poisoning; Sei | 2009 |
Ionic and cellular mechanisms underlying the development of acquired Brugada syndrome in patients treated with antidepressants.
Topics: Action Potentials; Adrenergic beta-Agonists; Amitriptyline; Animals; Anti-Arrhythmia Agents; Antidep | 2012 |
The relative toxicity of amitriptyline, bupivacaine, and levobupivacaine administered as rapid infusions in rats.
Topics: Amitriptyline; Anesthetics, Local; Animals; Antidepressive Agents, Tricyclic; Blood Pressure; Bupiva | 2003 |
[ACUTE INTOXICATION BY AMITRIPTYLINE WITH VENTRICULAR TACHYCARDIA. RECOVERY AFTER CARDIO-RESPIRATORY RESUSCITATION].
Topics: Amitriptyline; Heart; Humans; Poisoning; Resuscitation; Tachycardia; Tachycardia, Ventricular; Toxic | 1965 |
Beta-blocker treatment in an adolescent with amitriptyline intoxication.
Topics: Adolescent; Adrenergic beta-Antagonists; Amitriptyline; Antidepressive Agents, Tricyclic; Coma; Diag | 2007 |
Efficacy of magnesium sulfate for treatment of ventricular tachycardia in amitriptyline intoxication.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Child, Preschool; Humans; Magnesium Sulfate; Male; | 2007 |
Treatment of tricyclic antidepressant cardiac toxicity.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Child, Preschool; Humans; Hydrogen-Ion Concentratio | 2008 |
Mechanisms of ventricular arrhythmia during amitriptyline toxicity.
Topics: Action Potentials; Amitriptyline; Animals; Blood Pressure; Dogs; Female; Heart Conduction System; He | 1993 |
Prevention of tricyclic antidepressant-induced ventricular tachyarrhythmia by a specific bradycardic agent in a canine model.
Topics: Amitriptyline; Animals; Benzazepines; Cardiovascular Agents; Dogs; Electrocardiography; Female; Male | 1994 |
Effects of magnesium sulfate and lidocaine in the treatment of ventricular arrhythmias in experimental amitriptyline poisoning in the rat.
Topics: Amitriptyline; Analysis of Variance; Animals; Blood Pressure; Electrocardiography; Heart Rate; Lidoc | 1994 |
Arrhythmogenic right ventricular dysplasia (ARVD): an overlooked and underdiagnosed condition?
Topics: Adolescent; Amitriptyline; Death, Sudden; Diagnosis, Differential; Drug Overdose; Female; Heart Vent | 1997 |
Efficacy of long duration resuscitation and magnesium sulphate treatment in amitriptyline poisoning.
Topics: Amitriptyline; Anti-Arrhythmia Agents; Antidepressive Agents, Tricyclic; Cardiopulmonary Resuscitati | 2002 |