amitriptyline has been researched along with Status Epilepticus in 5 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Status Epilepticus: A prolonged seizure or seizures repeated frequently enough to prevent recovery between episodes occurring over a period of 20-30 minutes. The most common subtype is generalized tonic-clonic status epilepticus, a potentially fatal condition associated with neuronal injury and respiratory and metabolic dysfunction. Nonconvulsive forms include petit mal status and complex partial status, which may manifest as behavioral disturbances. Simple partial status epilepticus consists of persistent motor, sensory, or autonomic seizures that do not impair cognition (see also EPILEPSIA PARTIALIS CONTINUA). Subclinical status epilepticus generally refers to seizures occurring in an unresponsive or comatose individual in the absence of overt signs of seizure activity. (From N Engl J Med 1998 Apr 2;338(14):970-6; Neurologia 1997 Dec;12 Suppl 6:25-30)
Excerpt | Relevance | Reference |
---|---|---|
"This work was designed to study the influence of drugs during seizures and status epilepticus (SE) induced by pilocarpine and mortality in adult rats." | 7.73 | Effect of gabaergic, glutamatergic, antipsychotic and antidepressant drugs on pilocarpine-induced seizures and status epilepticus. ( Fonteles, MM; Freitas, RM; Sousa, FC; Viana, GS, 2006) |
"This work was designed to study the influence of drugs during seizures and status epilepticus (SE) induced by pilocarpine and mortality in adult rats." | 3.73 | Effect of gabaergic, glutamatergic, antipsychotic and antidepressant drugs on pilocarpine-induced seizures and status epilepticus. ( Fonteles, MM; Freitas, RM; Sousa, FC; Viana, GS, 2006) |
"7 mg/kg per dose) (the drug dosage was not known in 13 children)." | 1.33 | Acute amitriptyline intoxication: an analysis of 44 children. ( Akbayram, S; Akgün, C; Caksen, H; Erol, M; Odabaş, D; Ozbek, H; Tuncer, O; Yilmaz, C, 2006) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 4 (80.00) | 29.6817 |
2010's | 1 (20.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Olgun, H | 1 |
Yildirim, ZK | 1 |
Karacan, M | 1 |
Ceviz, N | 1 |
Clement, A | 1 |
Raney, JJ | 1 |
Wasserman, GS | 1 |
Lowry, JA | 1 |
Young, B | 1 |
Osvath, L | 1 |
Jones, D | 1 |
Socha, E | 1 |
Caksen, H | 1 |
Akbayram, S | 1 |
Odabaş, D | 1 |
Ozbek, H | 1 |
Erol, M | 1 |
Akgün, C | 1 |
Tuncer, O | 1 |
Yilmaz, C | 1 |
Freitas, RM | 1 |
Sousa, FC | 1 |
Viana, GS | 1 |
Fonteles, MM | 1 |
5 other studies available for amitriptyline and Status Epilepticus
Article | Year |
---|---|
Clinical, electrocardiographic, and laboratory findings in children with amitriptyline intoxication.
Topics: Adolescent; Amitriptyline; Antidepressive Agents, Tricyclic; Child; Child, Preschool; Drug Overdose; | 2009 |
Chronic amitriptyline overdose in a child.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Child; Drug Overdose; Electrocardiography; Female; | 2012 |
A novel EEG artifact in the intensive care unit.
Topics: Amitriptyline; Analgesics, Non-Narcotic; Anesthetics, Inhalation; Artifacts; Brain Ischemia; Electro | 2002 |
Acute amitriptyline intoxication: an analysis of 44 children.
Topics: Adolescent; Amitriptyline; Antidepressive Agents, Tricyclic; Child; Child, Preschool; Drug Overdose; | 2006 |
Effect of gabaergic, glutamatergic, antipsychotic and antidepressant drugs on pilocarpine-induced seizures and status epilepticus.
Topics: Amines; Amitriptyline; Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tri | 2006 |