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amitriptyline and Status Epilepticus

amitriptyline has been researched along with Status Epilepticus in 5 studies

Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.

Status Epilepticus: A prolonged seizure or seizures repeated frequently enough to prevent recovery between episodes occurring over a period of 20-30 minutes. The most common subtype is generalized tonic-clonic status epilepticus, a potentially fatal condition associated with neuronal injury and respiratory and metabolic dysfunction. Nonconvulsive forms include petit mal status and complex partial status, which may manifest as behavioral disturbances. Simple partial status epilepticus consists of persistent motor, sensory, or autonomic seizures that do not impair cognition (see also EPILEPSIA PARTIALIS CONTINUA). Subclinical status epilepticus generally refers to seizures occurring in an unresponsive or comatose individual in the absence of overt signs of seizure activity. (From N Engl J Med 1998 Apr 2;338(14):970-6; Neurologia 1997 Dec;12 Suppl 6:25-30)

Research Excerpts

ExcerptRelevanceReference
"This work was designed to study the influence of drugs during seizures and status epilepticus (SE) induced by pilocarpine and mortality in adult rats."7.73Effect of gabaergic, glutamatergic, antipsychotic and antidepressant drugs on pilocarpine-induced seizures and status epilepticus. ( Fonteles, MM; Freitas, RM; Sousa, FC; Viana, GS, 2006)
"This work was designed to study the influence of drugs during seizures and status epilepticus (SE) induced by pilocarpine and mortality in adult rats."3.73Effect of gabaergic, glutamatergic, antipsychotic and antidepressant drugs on pilocarpine-induced seizures and status epilepticus. ( Fonteles, MM; Freitas, RM; Sousa, FC; Viana, GS, 2006)
"7 mg/kg per dose) (the drug dosage was not known in 13 children)."1.33Acute amitriptyline intoxication: an analysis of 44 children. ( Akbayram, S; Akgün, C; Caksen, H; Erol, M; Odabaş, D; Ozbek, H; Tuncer, O; Yilmaz, C, 2006)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (80.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Olgun, H1
Yildirim, ZK1
Karacan, M1
Ceviz, N1
Clement, A1
Raney, JJ1
Wasserman, GS1
Lowry, JA1
Young, B1
Osvath, L1
Jones, D1
Socha, E1
Caksen, H1
Akbayram, S1
Odabaş, D1
Ozbek, H1
Erol, M1
Akgün, C1
Tuncer, O1
Yilmaz, C1
Freitas, RM1
Sousa, FC1
Viana, GS1
Fonteles, MM1

Other Studies

5 other studies available for amitriptyline and Status Epilepticus

ArticleYear
Clinical, electrocardiographic, and laboratory findings in children with amitriptyline intoxication.
    Pediatric emergency care, 2009, Volume: 25, Issue:3

    Topics: Adolescent; Amitriptyline; Antidepressive Agents, Tricyclic; Child; Child, Preschool; Drug Overdose;

2009
Chronic amitriptyline overdose in a child.
    Clinical toxicology (Philadelphia, Pa.), 2012, Volume: 50, Issue:5

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Child; Drug Overdose; Electrocardiography; Female;

2012
A novel EEG artifact in the intensive care unit.
    Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society, 2002, Volume: 19, Issue:5

    Topics: Amitriptyline; Analgesics, Non-Narcotic; Anesthetics, Inhalation; Artifacts; Brain Ischemia; Electro

2002
Acute amitriptyline intoxication: an analysis of 44 children.
    Human & experimental toxicology, 2006, Volume: 25, Issue:3

    Topics: Adolescent; Amitriptyline; Antidepressive Agents, Tricyclic; Child; Child, Preschool; Drug Overdose;

2006
Effect of gabaergic, glutamatergic, antipsychotic and antidepressant drugs on pilocarpine-induced seizures and status epilepticus.
    Neuroscience letters, 2006, Nov-13, Volume: 408, Issue:2

    Topics: Amines; Amitriptyline; Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tri

2006