amitriptyline has been researched along with Somatoform Disorders in 15 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Somatoform Disorders: Disorders having the presence of physical symptoms that suggest a general medical condition but that are not fully explained by another medical condition, by the direct effects of a substance, or by another mental disorder. The MEDICALLY UNEXPLAINED SYMPTOMS must cause clinically significant distress or impairment in social, occupational, or other areas of functioning. In contrast to FACTITIOUS DISORDERS and MALINGERING, the physical symptoms are not under voluntary control. (APA, DSM-V)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to explore the efficacy of buspirone (BSR), in comparison with amitriptyline (AML) in the prophylactic treatment of chronic tension-type headache (CTH), in an open and randomized clinical trial." | 9.08 | Buspirone vs amitriptyline in the treatment of chronic tension-type headache. ( Gatzonis, S; Ilias, A; Mitsikostas, DD; Thomas, A, 1997) |
| "The study describes a sequential analysis of depression-related physical symptoms and their relationship to imipramine and amitriptyline plasma levels over 4 weeks of treatment in 79 unipolar and bipolar patients hospitalized for major depressive disorder." | 9.07 | The pattern of physical symptom changes in major depressive disorder following treatment with amitriptyline or imipramine. ( Bowden, CL; Casper, RC; Davis, JM; Hanin, I; Katz, MM; Koslow, SH, 1994) |
| "A group of forty patients who presented to their general practitioner with depression or somatic complaints, which were considered to be due to depression, were included in a double-blind trial of dothiepin and amitriptyline." | 9.05 | A double-blind study of dothiepin hydrochloride (Prothiaden) and amitriptyline in out-patients with masked depression. ( Dahl, LE; Dencker, SJ; Lundin, L, 1981) |
| "The aim of this study was to explore the efficacy of buspirone (BSR), in comparison with amitriptyline (AML) in the prophylactic treatment of chronic tension-type headache (CTH), in an open and randomized clinical trial." | 5.08 | Buspirone vs amitriptyline in the treatment of chronic tension-type headache. ( Gatzonis, S; Ilias, A; Mitsikostas, DD; Thomas, A, 1997) |
| "The study describes a sequential analysis of depression-related physical symptoms and their relationship to imipramine and amitriptyline plasma levels over 4 weeks of treatment in 79 unipolar and bipolar patients hospitalized for major depressive disorder." | 5.07 | The pattern of physical symptom changes in major depressive disorder following treatment with amitriptyline or imipramine. ( Bowden, CL; Casper, RC; Davis, JM; Hanin, I; Katz, MM; Koslow, SH, 1994) |
| "A group of forty patients who presented to their general practitioner with depression or somatic complaints, which were considered to be due to depression, were included in a double-blind trial of dothiepin and amitriptyline." | 5.05 | A double-blind study of dothiepin hydrochloride (Prothiaden) and amitriptyline in out-patients with masked depression. ( Dahl, LE; Dencker, SJ; Lundin, L, 1981) |
| "Amitriptyline was administered and the dose was gradually increased up to a daily dose of 250 mg." | 2.72 | Efficacy of amitriptyline for treatment of somatoform pain disorder in the orofacial region: A case series. ( Ikawa, M; Ikeuchi, S; Yamada, K, 2006) |
| "Mirtazapine-treated patients demonstrated a statistically significant (p < or = ." | 2.40 | A meta-analysis of eight randomized, double-blind, controlled clinical trials of mirtazapine for the treatment of patients with major depression and symptoms of anxiety. ( Barkin, RL; Fawcett, J, 1998) |
| "Eight cases of glossodynia arising in the context of an endogenous depression are reported and the case histories of four of them are presented." | 1.27 | [Vital disorders of the mouth (glossodynia) in depressive involutional psychoses]. ( Maier, C, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (26.67) | 18.7374 |
| 1990's | 6 (40.00) | 18.2507 |
| 2000's | 3 (20.00) | 29.6817 |
| 2010's | 2 (13.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Suter, MR | 1 |
| Bhuiyan, ZA | 1 |
| Laedermann, CJ | 1 |
| Kuntzer, T | 1 |
| Schaller, M | 1 |
| Stauffacher, MW | 1 |
| Roulet, E | 1 |
| Abriel, H | 1 |
| Decosterd, I | 1 |
| Wider, C | 1 |
| Sommer, C | 1 |
| Häuser, W | 1 |
| Alten, R | 1 |
| Petzke, F | 1 |
| Späth, M | 1 |
| Tölle, T | 1 |
| Uçeyler, N | 1 |
| Winkelmann, A | 1 |
| Winter, E | 1 |
| Bär, KJ | 1 |
| Ikawa, M | 1 |
| Yamada, K | 1 |
| Ikeuchi, S | 1 |
| Gumus, II | 1 |
| Sarifakioglu, E | 1 |
| Uslu, H | 1 |
| Turhan, NO | 1 |
| Ghoreishi, A | 1 |
| Dahl, LE | 1 |
| Dencker, SJ | 1 |
| Lundin, L | 1 |
| Maany, I | 1 |
| Casper, RC | 1 |
| Katz, MM | 1 |
| Bowden, CL | 1 |
| Davis, JM | 1 |
| Koslow, SH | 1 |
| Hanin, I | 1 |
| Deary, IJ | 1 |
| Wilson, JA | 1 |
| Mitsikostas, DD | 1 |
| Gatzonis, S | 1 |
| Thomas, A | 1 |
| Ilias, A | 1 |
| Fawcett, J | 1 |
| Barkin, RL | 1 |
| Van Kempen, GM | 1 |
| Zitman, FG | 1 |
| Linssen, AC | 1 |
| Edelbroek, PM | 1 |
| Davis, RW | 1 |
| Davidson, J | 1 |
| Pelton, S | 1 |
| Maier, C | 1 |
3 reviews available for amitriptyline and Somatoform Disorders
| Article | Year |
|---|---|
[Drug therapy of fibromyalgia syndrome. Systematic review, meta-analysis and guideline].
Topics: Amitriptyline; Analgesics; Analgesics, Opioid; Antidepressive Agents; Anxiety Disorders; Combined Mo | 2012 |
Vulvodynia: case report and review of literature.
Topics: Adult; Amitriptyline; Female; Humans; Pelvic Pain; Selective Serotonin Reuptake Inhibitors; Somatofo | 2008 |
A meta-analysis of eight randomized, double-blind, controlled clinical trials of mirtazapine for the treatment of patients with major depression and symptoms of anxiety.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amitriptyline; Antidepressive Agents, Tricyclic; Depress | 1998 |
7 trials available for amitriptyline and Somatoform Disorders
| Article | Year |
|---|---|
Efficacy of amitriptyline for treatment of somatoform pain disorder in the orofacial region: A case series.
Topics: Adult; Aged; Amitriptyline; Analgesics, Non-Narcotic; Facial Pain; Female; Humans; Male; Middle Aged | 2006 |
A double-blind study of dothiepin hydrochloride (Prothiaden) and amitriptyline in out-patients with masked depression.
Topics: Adult; Aged; Amitriptyline; Clinical Trials as Topic; Depression; Dibenzothiepins; Dothiepin; Double | 1981 |
The pattern of physical symptom changes in major depressive disorder following treatment with amitriptyline or imipramine.
Topics: Adult; Affect; Amitriptyline; Appetite; Arousal; Bipolar Disorder; Body Weight; Depressive Disorder; | 1994 |
Problems in treating globus pharyngis.
Topics: Adult; Amitriptyline; Anxiety; Conversion Disorder; Depression; Double-Blind Method; Female; Humans; | 1994 |
Buspirone vs amitriptyline in the treatment of chronic tension-type headache.
Topics: Adult; Amitriptyline; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Anxiety; Buspirone; Dep | 1997 |
Biochemical measures in patients with a somatoform pain disorder, before, during, and after treatment with amitriptyline with or without flupentixol.
Topics: Adult; Amitriptyline; Depressive Disorder; Double-Blind Method; Drug Therapy, Combination; Female; F | 1992 |
Forms of atypical depression and their response to antidepressant drugs.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Anxiety Disorders; Bupropion; Clinical Trial | 1986 |
5 other studies available for amitriptyline and Somatoform Disorders
| Article | Year |
|---|---|
p.L1612P, a novel voltage-gated sodium channel Nav1.7 mutation inducing a cold sensitive paroxysmal extreme pain disorder.
Topics: Adolescent; Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Cell Line; Child; Cold Temperatu | 2015 |
A somatic type delusional disorder secondary to peripheral neuropathy: a case report.
Topics: Adult; Amitriptyline; Biperiden; Brachial Plexus; Delusions; Drug Overdose; Drug Therapy, Combinatio | 2008 |
Treatment of depression associated with Briquet's syndrome.
Topics: Adult; Amitriptyline; Antidepressive Agents; Depressive Disorder; Female; Humans; Imipramine; Male; | 1981 |
Comments on 'A controlled study of psychotherapy and amitriptyline used individually and in combination in the treatment of chronic intractable, 'psychogenic' pain, by I. Pilowsky and C.G. Barrow, Pain, 40 (1990) 3-19.
Topics: Amitriptyline; Humans; Pain, Intractable; Psychophysiologic Disorders; Somatoform Disorders; Termino | 1990 |
[Vital disorders of the mouth (glossodynia) in depressive involutional psychoses].
Topics: Aged; Amitriptyline; Chlorpromazine; Depressive Disorder, Major; Drug Therapy, Combination; Female; | 1986 |