Page last updated: 2024-10-22

amitriptyline and Sleep Apnea, Obstructive

amitriptyline has been researched along with Sleep Apnea, Obstructive in 3 studies

Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.

Sleep Apnea, Obstructive: A disorder characterized by recurrent apneas during sleep despite persistent respiratory efforts. It is due to upper airway obstruction. The respiratory pauses may induce HYPERCAPNIA or HYPOXIA. Cardiac arrhythmias and elevation of systemic and pulmonary arterial pressures may occur. Frequent partial arousals occur throughout sleep, resulting in relative SLEEP DEPRIVATION and daytime tiredness. Associated conditions include OBESITY; ACROMEGALY; MYXEDEMA; micrognathia; MYOTONIC DYSTROPHY; adenotonsilar dystrophy; and NEUROMUSCULAR DISEASES. (From Adams et al., Principles of Neurology, 6th ed, p395)

Research Excerpts

ExcerptRelevanceReference
" The workup included an endocrinological examination, which revealed a moderately elevated urine normetanephrine level, suggesting the possibility of a pheochromocytoma."3.80Obstructive sleep apnea and tricyclic antidepressant use presenting as a pseudopheochromocytoma in an active duty sailor: a case report. ( Brainard, T, 2014)
"We present a novel case of migraine headache in a gentleman with Klinefelter's syndrome and HFI, along with a discussion of possible pathophysiologic mechanisms underlying both the headache and the HFI."1.34Headache in a patient with Klinefelter's syndrome and hyperostosis frontalis interna. ( Liebeskind, DS; Ramchandren, S, 2007)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brainard, T1
Smith, SS1
Dingwall, K1
Jorgenson, G1
Douglas, J1
Ramchandren, S1
Liebeskind, DS1

Other Studies

3 other studies available for amitriptyline and Sleep Apnea, Obstructive

ArticleYear
Obstructive sleep apnea and tricyclic antidepressant use presenting as a pseudopheochromocytoma in an active duty sailor: a case report.
    Military medicine, 2014, Volume: 179, Issue:1

    Topics: Adrenal Gland Neoplasms; Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Diagnosis, Differen

2014
Associations between the use of common medications and sleep architecture in patients with untreated obstructive sleep apnea.
    Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2006, Apr-15, Volume: 2, Issue:2

    Topics: Adrenergic beta-Antagonists; Amitriptyline; Antidepressive Agents; Aspirin; Drug Therapy; Female; Fl

2006
Headache in a patient with Klinefelter's syndrome and hyperostosis frontalis interna.
    The journal of headache and pain, 2007, Volume: 8, Issue:6

    Topics: Adult; Amitriptyline; Analgesics, Non-Narcotic; Humans; Hyperostosis Frontalis Interna; Ischemic Att

2007