amitriptyline has been researched along with Sialorrhea in 12 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Sialorrhea: Increased salivary flow.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Clozapine is an antipsychotic drug recommended for resistant schizophrenia, but its widespread use is limited by adverse effects." | 7.83 | Very Low Dose Amitriptyline for Clozapine-Associated Sialorrhea. ( Praharaj, SK; Simlai, J; Sinha, S, 2016) |
| "Clozapine is an antipsychotic drug recommended for resistant schizophrenia, but its widespread use is limited by adverse effects." | 3.83 | Very Low Dose Amitriptyline for Clozapine-Associated Sialorrhea. ( Praharaj, SK; Simlai, J; Sinha, S, 2016) |
| " However, 3 patients, receiving amythryptiline in dosage 50 mg/day, experienced side effects (constipation, accommodation disturbances, dry mouth, sleepiness and poor concentration)." | 2.71 | [Pharmacological therapy of sialorrhea in patients with motor neuron disease]. ( Alekhin, AV; Koneva, ON; Levitskiĭ, GN; Morgunova, MS; Serdiuk, AV; Skvortsova, VI, 2005) |
| "Drooling is a distressing symptom for adults with neurological conditions and can be challenging for health professionals." | 2.48 | The management of drooling in adults with neurological conditions. ( Rowson, J; Squires, N; Wills, A, 2012) |
| "Familial rectal pain is a very rare entity that must always be considered as a possible aetiology of any life-threatening event in an infant because of the availability of a very effective treatment." | 1.33 | Familial rectal pain: a familial autonomic disorder as a cause of paroxysmal attacks in the newborn baby. ( Arbuès, AS; Bednarek, N; Morville, P; Motte, J; Plouin, P; Sabouraud, P, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (8.33) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 5 (41.67) | 29.6817 |
| 2010's | 4 (33.33) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Cereda, G | 1 |
| Boscutti, A | 1 |
| Lazzaretti, M | 1 |
| Enrico, P | 1 |
| Brambilla, P | 1 |
| Kawasaki, K | 1 |
| Nagamine, T | 1 |
| Watanabe, T | 1 |
| Suga, T | 1 |
| Tu, TTH | 1 |
| Sugawara, S | 1 |
| Mikuzuki, L | 1 |
| Miura, A | 1 |
| Shinohara, Y | 1 |
| Yoshikawa, T | 1 |
| Takenoshita, M | 1 |
| Toyofuku, A | 1 |
| Sinha, S | 1 |
| Simlai, J | 1 |
| Praharaj, SK | 2 |
| Pinto, S | 1 |
| Gromicho, M | 1 |
| de Carvalho, M | 1 |
| Aggarwal, A | 1 |
| Garg, A | 1 |
| Jiloha, RC | 1 |
| Squires, N | 1 |
| Wills, A | 1 |
| Rowson, J | 1 |
| LOEW, D | 1 |
| TAESCHLER, M | 1 |
| Palau Galindo, A | 1 |
| Ciutat Benet, M | 1 |
| Fernández González, A | 1 |
| Planellas Boix, M | 1 |
| Levitskiĭ, GN | 1 |
| Alekhin, AV | 1 |
| Serdiuk, AV | 1 |
| Morgunova, MS | 1 |
| Koneva, ON | 1 |
| Skvortsova, VI | 1 |
| Bednarek, N | 1 |
| Arbuès, AS | 1 |
| Motte, J | 1 |
| Sabouraud, P | 1 |
| Plouin, P | 1 |
| Morville, P | 1 |
| Arora, M | 1 |
| Copp, PJ | 1 |
| Lament, R | 1 |
| Tennent, TG | 1 |
1 review available for amitriptyline and Sialorrhea
| Article | Year |
|---|---|
The management of drooling in adults with neurological conditions.
Topics: Administration, Cutaneous; Adult; Amitriptyline; Atropine; Behavior Therapy; Botulinum Toxins, Type | 2012 |
1 trial available for amitriptyline and Sialorrhea
| Article | Year |
|---|---|
[Pharmacological therapy of sialorrhea in patients with motor neuron disease].
Topics: Adrenergic Uptake Inhibitors; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Botulinum Toxin | 2005 |
10 other studies available for amitriptyline and Sialorrhea
| Article | Year |
|---|---|
Amitriptyline for clozapine-induced hypersalivation: A case series.
Topics: Amitriptyline; Antipsychotic Agents; Clozapine; Humans; Schizophrenia; Sialorrhea | 2022 |
An increase in salivary flow with amitriptyline may indicate treatment resistance in burning mouth syndrome.
Topics: Adult; Aged; Amitriptyline; Analgesics, Non-Narcotic; Burning Mouth Syndrome; Female; Humans; Male; | 2018 |
Very Low Dose Amitriptyline for Clozapine-Associated Sialorrhea.
Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Clozapine; Humans; Male; Schi | 2016 |
Sialorrhoea and reversals in ALS functional rating scale.
Topics: Aged; Amitriptyline; Amyotrophic Lateral Sclerosis; Atropine; Cholinergic Antagonists; Deglutition D | 2017 |
Trihexyphenidyl (benzhexol) in clozapine-induced nocturnal enuresis and sialorrhea.
Topics: Amitriptyline; Antipsychotic Agents; Clozapine; Humans; Male; Muscarinic Antagonists; Nocturnal Enur | 2009 |
[RESEARCH ON ANTICHOLINERGIC EFFECTS OF ANTIDEPRESSIVE SUBSTANCES IN THE RABBIT].
Topics: Amitriptyline; Animals; Antidepressive Agents; Atropine; Bradycardia; Cholinergic Antagonists; Desip | 1964 |
[Therapeutic utility of a side-effect to control sialorrhoea].
Topics: Amitriptyline; Cholinergic Antagonists; Humans; Male; Middle Aged; Sialorrhea; Time Factors | 2004 |
Familial rectal pain: a familial autonomic disorder as a cause of paroxysmal attacks in the newborn baby.
Topics: Amitriptyline; Anticonvulsants; Apnea; Autonomic Nervous System Diseases; Bradycardia; Bronchial Spa | 2005 |
Amitriptyline for clozapine-induced nocturnal enuresis and sialorrhoea.
Topics: Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Clozapine; Drug Admini | 2007 |
Amitriptyline in clozapine-induced sialorrhoea.
Topics: Amitriptyline; Clozapine; Drug Administration Schedule; Humans; Schizophrenia; Sialorrhea | 1991 |