amitriptyline has been researched along with Reflex Sympathetic Dystrophy in 10 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Reflex Sympathetic Dystrophy: A syndrome characterized by severe burning pain in an extremity accompanied by sudomotor, vasomotor, and trophic changes in bone without an associated specific nerve injury. This condition is most often precipitated by trauma to soft tissue or nerve complexes. The skin over the affected region is usually erythematous and demonstrates hypersensitivity to tactile stimuli and erythema. (Adams et al., Principles of Neurology, 6th ed, p1360; Pain 1995 Oct;63(1):127-33)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We prospectively investigated the outcome of a combination therapy of oral amitriptyline and sympathetic ganglion blockade on 10 patients suffering from reflex sympathetic dystrophy of the upper extremity for at least three months." | 7.72 | Sympathetic blockade and amitriptyline in the treatment of reflex sympathetic dystrophy. ( Gulec, A; Karadasli, H; Karakurum, G; Oner, U; Pirbudak, L; Satana, T, 2003) |
| "We prospectively investigated the outcome of a combination therapy of oral amitriptyline and sympathetic ganglion blockade on 10 patients suffering from reflex sympathetic dystrophy of the upper extremity for at least three months." | 3.72 | Sympathetic blockade and amitriptyline in the treatment of reflex sympathetic dystrophy. ( Gulec, A; Karadasli, H; Karakurum, G; Oner, U; Pirbudak, L; Satana, T, 2003) |
| "Treatment of neuropathic pain in children is challenging, and requires a multimodal approach of pharmacologic, physical, and psychological therapies; however there is little evidence to guide practice." | 2.82 | A randomized controlled trial of amitriptyline versus gabapentin for complex regional pain syndrome type I and neuropathic pain in children. ( Amaria, K; Brown, S; Campbell, F; Johnston, B; McGrath, P; Pehora, C; Watkins, J, 2016) |
| "A diagnosis of reflex sympathetic dystrophy syndrome or complex regional pain syndrome type I induced by pacemaker insertion was made." | 1.42 | Complex regional pain syndrome type I following pacemaker implantation. ( Kamath, S; Rao, BS, 2015) |
| "Polycythemia vera has not been described previously as a contributing factor in CRPS." | 1.31 | Polycythemia vera presenting as complex regional pain syndrome of the lower limbs. ( McCrory, C; Westerling, D, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 6 (60.00) | 29.6817 |
| 2010's | 3 (30.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brown, S | 1 |
| Johnston, B | 1 |
| Amaria, K | 1 |
| Watkins, J | 1 |
| Campbell, F | 1 |
| Pehora, C | 1 |
| McGrath, P | 1 |
| Kamath, S | 1 |
| Rao, BS | 1 |
| Vas, L | 1 |
| Pai, R | 1 |
| Karakurum, G | 1 |
| Pirbudak, L | 1 |
| Oner, U | 1 |
| Gulec, A | 1 |
| Karadasli, H | 1 |
| Satana, T | 1 |
| Silviu, B | 1 |
| Mark, WJ | 1 |
| Reuben, I | 1 |
| Shvartzman, P | 1 |
| Lalwani, K | 1 |
| Shoham, A | 1 |
| Koh, JL | 1 |
| McGraw, T | 1 |
| Millecamps, M | 1 |
| Coderre, TJ | 1 |
| Reinhard, DL | 1 |
| Whyte, J | 1 |
| Sandel, ME | 1 |
| Maneksha, FR | 1 |
| Mirza, H | 1 |
| Poppers, PJ | 1 |
| McCrory, C | 1 |
| Westerling, D | 1 |
1 trial available for amitriptyline and Reflex Sympathetic Dystrophy
| Article | Year |
|---|---|
A randomized controlled trial of amitriptyline versus gabapentin for complex regional pain syndrome type I and neuropathic pain in children.
Topics: Adolescent; Amines; Amitriptyline; Analgesics; Child; Cyclohexanecarboxylic Acids; Female; Gabapenti | 2016 |
9 other studies available for amitriptyline and Reflex Sympathetic Dystrophy
| Article | Year |
|---|---|
Complex regional pain syndrome type I following pacemaker implantation.
Topics: Adrenergic Uptake Inhibitors; Aged; Amitriptyline; Drug Therapy, Combination; Female; Humans; Pacema | 2015 |
Successful reversal of complex regional pain syndrome type 1 of both upper extremities in five patients.
Topics: Aged; Amitriptyline; Analgesics; Combined Modality Therapy; Female; gamma-Aminobutyric Acid; Humans; | 2012 |
Sympathetic blockade and amitriptyline in the treatment of reflex sympathetic dystrophy.
Topics: Adult; Amitriptyline; Analgesics, Non-Narcotic; Anesthetics, Local; Bupivacaine; Drug Therapy, Combi | 2003 |
Complex Regional Pain Syndrome type I following radial artery cardiac catheterization.
Topics: Amitriptyline; Analgesics, Non-Narcotic; Anesthetics, Local; Angina, Unstable; Cardiac Catheterizati | 2005 |
Use of oxcarbazepine to treat a pediatric patient with resistant complex regional pain syndrome.
Topics: Amines; Amitriptyline; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; | 2005 |
Rats with chronic post-ischemia pain exhibit an analgesic sensitivity profile similar to human patients with complex regional pain syndrome--type I.
Topics: Amitriptyline; Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dos | 2008 |
Improved arousal and initiation following tricyclic antidepressant use in severe brain injury.
Topics: Activities of Daily Living; Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Arousal; Brain I | 1996 |
Complex regional pain syndrome (CRPS) with resistance to local anesthetic block: a case report.
Topics: Acetates; Amines; Amitriptyline; Analgesia, Epidural; Analgesics; Analgesics, Non-Narcotic; Analgesi | 2000 |
Polycythemia vera presenting as complex regional pain syndrome of the lower limbs.
Topics: Acetaminophen; Aged; Amitriptyline; Analgesics, Non-Narcotic; Drug Therapy, Combination; Female; Hum | 2001 |