amitriptyline has been researched along with Purpura, Thrombocytopenic, Idiopathic in 2 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Purpura, Thrombocytopenic, Idiopathic: Thrombocytopenia occurring in the absence of toxic exposure or a disease associated with decreased platelets. It is mediated by immune mechanisms, in most cases IMMUNOGLOBULIN G autoantibodies which attach to platelets and subsequently undergo destruction by macrophages. The disease is seen in acute (affecting children) and chronic (adult) forms.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kumar, S | 1 |
| König, F | 1 |
| Stumpp, W | 1 |
| Wolfersdorf, M | 1 |
| Leibfarth, M | 1 |
| Fuchs, G | 1 |
| Kaschka, WP | 1 |
2 other studies available for amitriptyline and Purpura, Thrombocytopenic, Idiopathic
| Article | Year |
|---|---|
Painful mononeuritis multiplex in idiopathic thrombocytopenic purpura.
Topics: Amitriptyline; Analgesics, Non-Narcotic; Anticonvulsants; Carbamazepine; Child; Drug Therapy, Combin | 2005 |
[Follow-up of Werlhof disease after onset of treatment with maprotiline].
Topics: Amitriptyline; Cilazapril; Depressive Disorder; Dose-Response Relationship, Drug; Drug Therapy, Comb | 1995 |